Reactome | CPLX1 [cytosol]

CPLX1 [cytosol]

Stable Identifier

R-HSA-210385

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

complexin 1

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:O14810 CPLX1

Gene Names

CPLX1

Chain

chain:1-134

Reference Genes

BioGPS Gene:10815 CPLX1

COSMIC (genes):CPLX1 CPLX1

CTD Gene:10815 CPLX1

dbSNP Gene:10815 CPLX1

ENSEMBL:ENSG00000168993 CPLX1

HGNC:2309 CPLX1

KEGG:hsa:10815 CPLX1

Monarch:10815 CPLX1

NCBI Gene:10815 CPLX1

OMIM:605032 CPLX1

UCSC:O14810 CPLX1

Reference Transcript

RefSeq:NM_006651.4 CPLX1

Other Identifiers

10815

11758141_s_at

16973365

223500_PM_at

223500_at

2756632

2756633

2756634

2756635

2756636

2756637

2756638

2756639

2756640

2756649

2756650

2756651

2756654

2756656

2756657

2756658

56134_at

8098782

A_23_P212812

A_24_P51909

GE62156

GO:0000149

GO:0005515

GO:0005737

GO:0005829

GO:0006836

GO:0006887

GO:0007268

GO:0016079

GO:0016192

GO:0017075

GO:0017157

GO:0019905

GO:0030073

GO:0030425

GO:0031201

GO:0031630

GO:0032991

GO:0042995

GO:0043025

GO:0043195

GO:0043204

GO:0044305

GO:0045202

GO:0050804

GO:0070032

GO:0070554

GO:0098685

GO:0098793

GO:0098794

GO:0098978

GO:0099145

HMNXSV003000232

ILMN_1801703

PH_hs_0013187

TC04000956.hg

g12803306_3p_at

Participates

as an input of

as an output of

as a component of

Inferred To

cplx1 [cytosol] (Danio rerio)

cplx1 [cytosol] (Xenopus tropicalis)

cpx-1 [cytosol] (Caenorhabditis elegans)

Cplx1 [cytosol] (Mus musculus)

Cplx1 [cytosol] (Rattus norvegicus)

CPLX1 [cytosol] (Bos taurus)

CPLX1 [cytosol] (Canis familiaris)

CPLX1 [cytosol] (Gallus gallus)

CPLX1 [cytosol] (Sus scrofa)

cpx [cytosol] (Drosophila melanogaster)

Cross References

RefSeq

NP_006642.1

ENSEMBL

ENST00000304062, ENSG00000168993, ENSP00000305613

OpenTargets

ENSG00000168993

GeneCards

CPLX1

HPA

ENSG00000168993-CPLX1

PRO

O14810

Pharos - Targets

O14810

Orphanet

CPLX1

PDB

3RK3, 3RL0

Interactors (6)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P60880-2 SNAP25			0.733	6
UniProt:P63027 VAMP2	20	VAMP2 [clathrin-sculpted monoamine transport vesicle membrane] (R-HSA-379363) VAMP2 [plasma membrane] (R-HSA-210516) VAMP2 [clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane] (R-HSA-917738) VAMP2 [clathrin-sculpted glutamate transport vesicle membrane] (R-HSA-210365) VAMP2 [synaptic vesicle membrane] (R-HSA-181517) VAMP2(59-116) [synaptic vesicle membrane] (R-HSA-5250891) VAMP2(2-58) [cytosol] (R-HSA-194815) VAMP2(2-76) [cytosol] (R-HSA-194802) VAMP2(77-116) [synaptic vesicle membrane] (R-HSA-5228355) VAMP2(60-116) [synaptic vesicle membrane] (R-HSA-5250615) VAMP2(2-59) [cytosol] (R-HSA-194797) VAMP2(82-116) [synaptic vesicle membrane] (R-HSA-5250961) VAMP2(2-81) [cytosol] (R-HSA-5250970) VAMP2 [clathrin-coated endocytic vesicle membrane] (R-HSA-8869129) VAMP2 [secretory granule membrane] (R-HSA-376363) VAMP2 [cytosol] (R-HSA-9609882) VAMP2 [endoplasmic reticulum membrane] (R-HSA-9609886) VAMP2 [cytoplasmic vesicle membrane] (R-HSA-1449630) VAMP2 [lysosomal membrane] (R-HSA-432703) VAMP2 [Golgi membrane] (R-HSA-375425)	0.656	3
UniProt:P32851 Stx1a	2	Stx1a [plasma membrane] (R-RNO-6794247) Stx1a [cytosol] (R-RNO-9609866)	0.656	3
UniProt:Q15836 VAMP3	6	VAMP3 [recycling endosome membrane] (R-HSA-2029063) VAMP3 [phagocytic vesicle membrane] (R-HSA-2029013) VAMP3 [plasma membrane] (R-HSA-8867599) VAMP3 [clathrin-coated endocytic vesicle membrane] (R-HSA-8869130) VAMP3 [trans-Golgi network membrane] (R-HSA-6814624) VAMP3 [transport vesicle] (R-HSA-6814625)	0.527	2
UniProt:Q6PUV4 CPLX2			0.527	3
UniProt:P06028 GYPB	1	GYPB [plasma membrane] (R-HSA-8867209)	0.527	2

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