Tyrosine is diiodinated

Stable Identifier
R-HSA-209973
Type
Reaction [transition]
Species
Homo sapiens
Compartment
extracellular region, plasma membrane
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Tyrosine is diiodinated
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Tyrosines can be iodinated in thyroglobulin to produce precursors for thyroid hormone synthesis.

Literature References
PubMed ID Title Journal Year
67547 Biosynthesis of thyroid hormone: basic and clinical aspects

Niepomniszcze, H, Degroot, LJ

Metabolism 1977
Participants
Input
Output
Participates
as an event of
Catalyst Activity

peroxidase activity of TPO [plasma membrane]

Physical Entity
TPO [plasma membrane] (Homo sapiens)
Activity
peroxidase activity (GO:0004601)
Orthologous Events
Tyrosine is diiodinated (Bos taurus)
Tyrosine is diiodinated (Caenorhabditis elegans)
Tyrosine is diiodinated (Canis familiaris)
Tyrosine is diiodinated (Dictyostelium discoideum)
Tyrosine is diiodinated (Drosophila melanogaster)
Tyrosine is diiodinated (Gallus gallus)
Tyrosine is diiodinated (Mus musculus)
Tyrosine is diiodinated (Rattus norvegicus)
Tyrosine is diiodinated (Sus scrofa)
Tyrosine is diiodinated (Xenopus tropicalis)
Authored
Jassal, B  (2008-10-01)
Reviewed
D'Eustachio, P  (2008-05-28)
Created
Jassal, B  (2008-01-08)
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