Photolytic cleavage and thermal isomerization of 7-dehydroCHOL

Stable Identifier
R-HSA-209754
Type
Reaction [omitted]
Species
Homo sapiens
Compartment
ReviewStatus
5/5
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The skin's exposure to UV rays from sunlight induces the photolytic cleavage of 7-dehydrocholesterol to previtamin D3. This is followed by thermal isomerization to form vitamin D3 (VD3, cholecalciferol) (Holick et al. 1977).
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