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NGF ligand:p75NTR:Phospho-IRAK1:TRAF6 [plasma membrane]
Stable Identifier
R-HSA-209569
Type
Complex
Species
Homo sapiens
Compartment
plasma membrane
Locations in the PathwayBrowser
Expand all
Signal Transduction (Homo sapiens)
Death Receptor Signaling (Homo sapiens)
p75 NTR receptor-mediated signalling (Homo sapiens)
p75NTR signals via NF-kB (Homo sapiens)
NF-kB is activated and signals survival (Homo sapiens)
IKKbeta is activated (Homo sapiens)
NGF ligand:p75NTR:Phospho-IRAK1:TRAF6:p62:IKK-beta [plasma membrane] (Homo sapiens)
NGF ligand:p75NTR:Phospho-IRAK1:TRAF6:p62 [plasma membrane] (Homo sapiens)
NGF ligand:p75NTR:Phospho-IRAK1:TRAF6 [plasma membrane] (Homo sapiens)
p75NTR recruits signalling complexes (Homo sapiens)
IKK-beta is recruited (Homo sapiens)
NGF ligand:p75NTR:Phospho-IRAK1:TRAF6:p62 [plasma membrane] (Homo sapiens)
NGF ligand:p75NTR:Phospho-IRAK1:TRAF6 [plasma membrane] (Homo sapiens)
NGF ligand:p75NTR:Phospho-IRAK1:TRAF6:p62:IKK-beta [plasma membrane] (Homo sapiens)
NGF ligand:p75NTR:Phospho-IRAK1:TRAF6:p62 [plasma membrane] (Homo sapiens)
NGF ligand:p75NTR:Phospho-IRAK1:TRAF6 [plasma membrane] (Homo sapiens)
MYD88 dissociates (Homo sapiens)
NGF ligand:p75NTR:Phospho-IRAK1:TRAF6 [plasma membrane] (Homo sapiens)
TRAF6 is auto-ubiquitinated (Homo sapiens)
NGF ligand:p75NTR:Phospho-IRAK1:TRAF6:p62 [plasma membrane] (Homo sapiens)
NGF ligand:p75NTR:Phospho-IRAK1:TRAF6 [plasma membrane] (Homo sapiens)
p62 is recruited and forms a complex with TRAF6 (Homo sapiens)
NGF ligand:p75NTR:Phospho-IRAK1:TRAF6 [plasma membrane] (Homo sapiens)
NGF ligand:p75NTR:Phospho-IRAK1:TRAF6:p62 [plasma membrane] (Homo sapiens)
NGF ligand:p75NTR:Phospho-IRAK1:TRAF6 [plasma membrane] (Homo sapiens)
p62 recruits an atypical PKC (Homo sapiens)
NGF ligand:p75NTR:Phospho-IRAK1:TRAF6:p62 [plasma membrane] (Homo sapiens)
NGF ligand:p75NTR:Phospho-IRAK1:TRAF6 [plasma membrane] (Homo sapiens)
NGF ligand:p75NTR:Phospho-IRAK1:TRAF6:p62:aPKCi [plasma membrane] (Homo sapiens)
NGF ligand:p75NTR:Phospho-IRAK1:TRAF6:p62 [plasma membrane] (Homo sapiens)
NGF ligand:p75NTR:Phospho-IRAK1:TRAF6 [plasma membrane] (Homo sapiens)
Participants
components
mature NGF homodimer:p75NTR [plasma membrane]
(Homo sapiens)
p-S,T-IRAK1 [cytosol]
(Homo sapiens)
TRAF6 [cytosol]
(Homo sapiens)
Participates
as an output of
MYD88 dissociates (Homo sapiens)
as an input of
p62 is recruited and forms a complex with TRAF6 (Homo sapiens)
as a component of
NGF ligand:p75NTR:Phospho-IRAK1:TRAF6:p62 [plasma membrane] (Homo sapiens)
Inferred To
NGF ligand:p75NTR:Phospho-IRAK1:TRAF6 [plasma membrane]
(Bos taurus)
NGF ligand:p75NTR:Phospho-IRAK1:TRAF6 [plasma membrane]
(Canis familiaris)
NGF ligand:p75NTR:Phospho-IRAK1:TRAF6 [plasma membrane]
(Danio rerio)
NGF ligand:p75NTR:Phospho-IRAK1:TRAF6 [plasma membrane]
(Gallus gallus)
NGF ligand:p75NTR:Phospho-IRAK1:TRAF6 [plasma membrane]
(Mus musculus)
NGF ligand:p75NTR:Phospho-IRAK1:TRAF6 [plasma membrane]
(Rattus norvegicus)
NGF ligand:p75NTR:Phospho-IRAK1:TRAF6 [plasma membrane]
(Sus scrofa)
NGF ligand:p75NTR:Phospho-IRAK1:TRAF6 [plasma membrane]
(Xenopus tropicalis)
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