IkB is ubiquitinated and degraded

Stable Identifier
R-HSA-209536
Type
Reaction [binding]
Species
Homo sapiens
Compartment
cytosol
ReviewStatus
5/5
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IkB is ubiquitinated and degraded
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Once dissociated from NF-kB, the phosphorylated IkB protein is ubiquitinated at lysines 21 and 22, and degraded by the proteosome (Baldi et al 1996).

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Orthologous Events
IkB is ubiquitinated and degraded (Bos taurus)
IkB is ubiquitinated and degraded (Canis familiaris)
IkB is ubiquitinated and degraded (Danio rerio)
IkB is ubiquitinated and degraded (Drosophila melanogaster)
IkB is ubiquitinated and degraded (Gallus gallus)
IkB is ubiquitinated and degraded (Mus musculus)
IkB is ubiquitinated and degraded (Rattus norvegicus)
IkB is ubiquitinated and degraded (Sus scrofa)
IkB is ubiquitinated and degraded (Xenopus tropicalis)
Authored
Nasi, S  (2006-10-10)
Annibali, D  (2006-10-10)
Reviewed
Friedman, WJ  (2008-05-20)
Chao, MV  (2008-05-28)
Created
Jassal, B  (2007-12-19)
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