IKBA is phosphorylated by Phospho IKKB kinase

Stable Identifier
R-HSA-209087
Type
Reaction [transition]
Species
Homo sapiens
Compartment
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Human IKBA, orthologue of Drosophila Cactus (CACT), is phosphorylated by activated IKKB kinase at residues Ser32 and Ser36.

Literature References
PubMed ID Title Journal Year
12791687 Differential phosphorylation of the signal-responsive domain of I kappa B alpha and I kappa B beta by I kappa B kinases

Wu, C, Ghosh, S

J Biol Chem 2003
9346484 IKK-1 and IKK-2: cytokine-activated IkappaB kinases essential for NF-kappaB activation

Mercurio, F, Zhu, H, Murray, BW, Shevchenko, A, Bennett, BL, Li, J, Young, DB, Barbosa, M, Mann, M, Manning, A, Rao, A

Science 1997
Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
protein serine/threonine kinase activity of p-S177,S181-IKBKB [cytosol]
Physical Entity
Activity
Orthologous Events
Authored
Reviewed
Created