IKBA is phosphorylated by Phospho IKKB kinase

Stable Identifier
R-HSA-209087
Type
Reaction [transition]
Species
Homo sapiens
Compartment
ReviewStatus
5/5
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Human IKBA, orthologue of Drosophila Cactus (CACT), is phosphorylated by activated IKKB kinase at residues Ser32 and Ser36.
Literature References
PubMed ID Title Journal Year
9346484 IKK-1 and IKK-2: cytokine-activated IkappaB kinases essential for NF-kappaB activation

Bennett, BL, Rao, A, Barbosa, M, Shevchenko, A, Young, DB, Mann, M, Manning, A, Li, J, Mercurio, F, Murray, BW, Zhu, H

Science 1997
12791687 Differential phosphorylation of the signal-responsive domain of I kappa B alpha and I kappa B beta by I kappa B kinases

Wu, C, Ghosh, S

J Biol Chem 2003
Participants
Participates
Catalyst Activity

protein serine/threonine kinase activity of p-S177,S181-IKBKB [cytosol]

Orthologous Events
Authored
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