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GPC2 [lysosomal lumen]
Stable Identifier
R-HSA-2090060
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
lysosomal lumen
Synonyms
Glypican-2 component recommendedName: Secreted glypican-2 /component, GPC2_HUMAN
Locations in the PathwayBrowser
Expand all
Metabolism (Homo sapiens)
Metabolism of carbohydrates (Homo sapiens)
Glycosaminoglycan metabolism (Homo sapiens)
Heparan sulfate/heparin (HS-GAG) metabolism (Homo sapiens)
HS-GAG degradation (Homo sapiens)
Heparanase (HPSE) cleaves heparan sulfate from its proteoglycan (lysosome) (Homo sapiens)
HS core proteins [lysosomal lumen] (Homo sapiens)
GPC2 [lysosomal lumen] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q8N158 GPC2
Gene Names
GPC2
Chain
signal peptide:1-23, chain:24-554, chain:24-, propeptide:555-579
Reference Genes
BioGPS Gene:221914 GPC2
COSMIC (genes):GPC2 GPC2
CTD Gene:221914 GPC2
dbSNP Gene:221914 GPC2
ENSEMBL:ENSG00000213420 GPC2
ENSEMBL_homo_sapiens_GENE:ENSG00000213420.8 GPC2
HGNC:4450 GPC2
KEGG Gene (Homo sapiens):221914 GPC2
Monarch:221914 GPC2
NCBI Gene:221914 GPC2
OMIM:618446 GPC2
UCSC:Q8N158 GPC2
Reference Transcript
RefSeq:NM_152742.2 GPC2
Other Identifiers
11731828_at
11731829_x_at
17060515
221914
239422_3p_at
239422_PM_at
239422_at
3063808
3063809
3063810
3063811
3063812
3063813
3063815
3063816
3063817
3063819
3063823
3063825
3063826
3063827
3063829
3063830
8141463
8141466
GE480275
GO:0005515
GO:0005576
GO:0005764
GO:0005773
GO:0005783
GO:0005794
GO:0005796
GO:0005886
GO:0007224
GO:0009966
GO:0009986
GO:0010976
GO:0016020
GO:0016477
GO:0023052
GO:0030154
GO:0030182
GO:0030312
GO:0031012
GO:0043202
GO:0043226
GO:0045202
GO:0048856
GO:0048870
GO:0062023
GO:0098552
GO:1905475
HMNXSV003033372
Hs.211701.0.A1_3p_at
Hs.211701.0.A1_3p_x_at
ILMN_1651642
PH_hs_0012283
TC07001662.hg
Participates
as a member of
HS core proteins [lysosomal lumen] (Homo sapiens)
Other forms of this molecule
HS(6)-GPC2 [lysosomal lumen]
HS(1)-GPC2 [Golgi lumen]
HS(2)-GPC2 [Golgi lumen]
HS(3)-GPC2 [Golgi lumen]
HS(4)-GPC2 [Golgi lumen]
HS(6)-GPC2 [Golgi lumen]
HS(5)-GPC2 [Golgi lumen]
Heparan-GPC2 [Golgi lumen]
Heparan(1)-GPC2 [Golgi lumen]
Heparan(2)-GPC2 [Golgi lumen]
Heparan(4)-GPC2 [Golgi lumen]
Heparan(3)-GPC2 [Golgi lumen]
HS(4)-GPC2 [plasma membrane]
HS(6)-GPC2 [plasma membrane]
HS(2)-GPC2 [plasma membrane]
HS(1)-GPC2 [plasma membrane]
HS(3)-GPC2 [plasma membrane]
HS(5)-GPC2 [plasma membrane]
Gal-Gal-Xyl-GPC2 [Golgi lumen]
GlcA-Gal-Gal-Xyl-GPC2 [Golgi lumen]
Gal-Xyl-GPC2 [Golgi lumen]
XylS-GPC2 [Golgi lumen]
GPC2 [Golgi lumen]
Inferred To
lon-2 [lysosomal lumen]
(Caenorhabditis elegans)
GPC2 [lysosomal lumen]
(Bos taurus)
GPC2 [lysosomal lumen]
(Caenorhabditis elegans)
GPC2 [lysosomal lumen]
(Canis familiaris)
GPC2 [lysosomal lumen]
(Sus scrofa)
gpc2 [lysosomal lumen]
(Danio rerio)
gpc2 [lysosomal lumen]
(Xenopus tropicalis)
gpn-1 [lysosomal lumen]
(Caenorhabditis elegans)
Gpc2 [lysosomal lumen]
(Mus musculus)
Gpc2 [lysosomal lumen]
(Rattus norvegicus)
Homologues of GPC2 [lysosomal lumen]
(Caenorhabditis elegans)
dlp [lysosomal lumen]
(Drosophila melanogaster)
Cross References
RefSeq
NP_689955.1
OpenTargets
ENSG00000213420
HPA
ENSG00000213420-GPC2
GeneCards
Q8N158
Ensembl
ENST00000292377
,
ENSP00000292377
,
ENSG00000213420
PRO
Q8N158
Pharos - Targets
Q8N158
PDB
7T62
,
6WJL
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