HS(6)-GPC6 [lysosomal lumen]

Stable Identifier
R-HSA-2090051
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
lysosomal lumen
Synonyms
GPC6, Glypican-6 component recommendedName: Secreted glypican-6 /component, GPC6_HUMAN
Locations in the PathwayBrowser
Expand all
External Reference Information
External Reference
UniProt:Q9Y625 GPC6
Gene Names
GPC6, UNQ369/PRO705
Chain
signal peptide:1-23, chain:24-529, chain:24-, propeptide:530-555
Reference Genes
BioGPS Gene:10082 GPC6
COSMIC (genes):GPC6 GPC6
CTD Gene:10082 GPC6
dbSNP Gene:10082 GPC6
ENSEMBL:ENSG00000183098 GPC6
HGNC:4454 GPC6
KEGG:hsa:10082 GPC6
Monarch:10082 GPC6
NCBI Gene:10082 GPC6
OMIM:604404 GPC6
UCSC:Q9Y625 GPC6
Reference Transcript
Other Identifiers
10082
11726014_at
11726015_at
11726016_at
16775811
223730_PM_at
223730_at
227059_PM_at
227059_at
3496636
3496638
3496639
3496640
3496694
3496695
3496726
3496754
3496755
3496756
3496792
3496797
3496817
3496822
3496824
3496825
3496826
3496827
3496828
3496829
50307_at
74357_at
7969613
88630_at
A_14_P107388
A_14_P108843
A_14_P126561
A_23_P371682
A_32_P97169
GE58375
GO:0005515
GO:0005576
GO:0005634
GO:0005794
GO:0005796
GO:0005886
GO:0009966
GO:0009986
GO:0015026
GO:0016477
GO:0030312
GO:0031012
GO:0043202
GO:0043226
GO:0045202
GO:0048870
GO:0060089
GO:0062023
GO:0098552
GO:0098696
GO:0098978
HMNXSV003022177
Hs.75113.2.A1_3p_at
ILMN_1805216
ILMN_1912185
PH_hs_0026584
PH_hs_0037802
TC13000329.hg
g4877642_3p_at
Participates
as a member of
Other forms of this molecule
HS(4)-GPC6 [plasma membrane]
HS(6)-GPC6 [plasma membrane]
HS(2)-GPC6 [plasma membrane]
HS(1)-GPC6 [plasma membrane]
HS(3)-GPC6 [plasma membrane]
HS(5)-GPC6 [plasma membrane]
XylS-GPC6 [Golgi lumen]
Gal-Xyl-GPC6 [Golgi lumen]
GPC6 [Golgi lumen]
Gal-Gal-Xyl-GPC6 [Golgi lumen]
GlcA-Gal-Gal-Xyl-GPC6 [Golgi lumen]
HS(3)-GPC6 [Golgi lumen]
HS(4)-GPC6 [Golgi lumen]
HS(2)-GPC6 [Golgi lumen]
HS(1)-GPC6 [Golgi lumen]
Heparan(4)-GPC6 [Golgi lumen]
Heparan(3)-GPC6 [Golgi lumen]
Heparan(2)-GPC6 [Golgi lumen]
Heparan(1)-GPC6 [Golgi lumen]
Heparan-GPC6 [Golgi lumen]
HS(5)-GPC6 [Golgi lumen]
HS(6)-GPC6 [Golgi lumen]
GPC6 [lysosomal lumen]
Inferred To
gpc6a [lysosomal lumen] (Danio rerio)
lon-2 [lysosomal lumen] (Caenorhabditis elegans)
Gpc6 [lysosomal lumen] (Mus musculus)
Gpc6 [lysosomal lumen] (Rattus norvegicus)
Homologues of HS(6)-GPC6 [lysosomal lumen] (Caenorhabditis elegans)
GPC6 [lysosomal lumen] (Canis familiaris)
GPC6 [lysosomal lumen] (Sus scrofa)
gpc6 [lysosomal lumen] (Xenopus tropicalis)
gpn-1 [lysosomal lumen] (Caenorhabditis elegans)
HS(6)-GPC6 [lysosomal lumen] (Caenorhabditis elegans)
dlp [lysosomal lumen] (Drosophila melanogaster)
Modified Residues
Name
O-xylosyl-L-serine (ChEBI:63666) at unknown position
Modification
beta-D-IdoA-(1->4)-alpha-D-GlcNS6S-(1->4)-beta-D-IdoA2S-(1->4)-alpha-D-GlcNS3S-(1->4)-beta-D-GlcA-(1->3)-beta-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-Xyl-yl group
PsiMod Name
O-xylosyl-L-serine
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O3-xylosylserine.
Cross References
RefSeq
ENSEMBL
OpenTargets
HPA
PRO
Pharos - Targets
Orphanet
GlyGen
Interactors (1)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:P32249 GPR183  1 0.527 3
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