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HS(1)-GPC3
Stable Identifier
R-HSA-2076471
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
Golgi lumen
Synonyms
GPC3, Glypican-3, GPC3_HUMAN
Locations in the PathwayBrowser
Expand all
Metabolism (Homo sapiens)
Metabolism of carbohydrates (Homo sapiens)
Glycosaminoglycan metabolism (Homo sapiens)
Heparan sulfate/heparin (HS-GAG) metabolism (Homo sapiens)
HS-GAG biosynthesis (Homo sapiens)
GLCE epimerises GlcA to IdoA (Homo sapiens)
HS(1)-PGs [Golgi lumen] (Homo sapiens)
HS(1)-GPC3 [Golgi lumen] (Homo sapiens)
NDST1-4 can sulfate a glucosamine residue in heparan to form heparan sulfate (HS) (Homo sapiens)
HS(1)-PGs [Golgi lumen] (Homo sapiens)
HS(1)-GPC3 [Golgi lumen] (Homo sapiens)
Some HSPGs are secreted to the plasma membrane (Homo sapiens)
HSPGs [Golgi lumen] (Homo sapiens)
HS(1)-PGs [Golgi lumen] (Homo sapiens)
HS(1)-GPC3 [Golgi lumen] (Homo sapiens)
External Reference Information
External Reference
UniProt:P51654 GPC3
Gene Names
GPC3, OCI5
Chain
signal peptide:1-24, chain:25-, chain:25-, propeptide:-580
Reference Genes
BioGPS Gene:2719 GPC3
COSMIC (genes):GPC3 GPC3
CTD Gene:2719 GPC3
dbSNP Gene:2719 GPC3
ENSEMBL:ENSG00000147257 GPC3
HGNC:4451 GPC3
KEGG Gene (Homo sapiens):hsa:2719 GPC3
Monarch:2719 GPC3
NCBI Gene:2719 GPC3
OMIM:300037 GPC3
UCSC:P51654 GPC3
Reference Transcript
RefSeq:NM_004484.3 GPC3
RefSeq:NM_001164619.1 GPC3
RefSeq:NM_001164617.1 GPC3
Other Identifiers
0005130064
11729604_s_at
11752479_a_at
11754011_x_at
17114288
209220_at
2719
39350_at
4022456
4022457
4022458
4022459
4022460
4022461
4022462
4022463
4022479
4022499
4022506
4022508
4022517
4022518
4022567
4022568
4022583
4022584
6316
8175234
A_24_P57631
A_33_P3230264
A_33_P3326634
CCDS14638
CCDS55495
CCDS55496
ENSG00000147257
ENSP00000359854
ENSP00000377836
ENSP00000486325
ENST00000370818
ENST00000394299
ENST00000631057
EntrezGene:2719
g1237180_3p_at
GE58338
GO:0001523
GO:0001658
GO:0001822
GO:0005515
GO:0005576
GO:0005578
GO:0005615
GO:0005764
GO:0005788
GO:0005796
GO:0005886
GO:0005887
GO:0006024
GO:0006027
GO:0008285
GO:0009653
GO:0009887
GO:0009948
GO:0010171
GO:0010466
GO:0016020
GO:0030203
GO:0030282
GO:0030316
GO:0030324
GO:0030414
GO:0030513
GO:0031225
GO:0035116
GO:0040008
GO:0043202
GO:0043395
GO:0043687
GO:0044267
GO:0045732
GO:0045807
GO:0045879
GO:0045880
GO:0045926
GO:0046326
GO:0046658
GO:0050680
GO:0060422
GO:0060976
GO:0070062
GO:0072111
GO:0072138
GO:0072180
GO:0072203
GO:0090090
GO:2000096
GPC3
GPC3-201
GPC3-202
GPC3-204
HGNC:4451
HPA006316
Hs.644108
I6QTG3
ILMN_1799759
ILMN_2051972
L47125_s_at
LRG_505
LRG_505t1
MIM:194070
MIM:300037
MIM:312870
NM_001164617
NM_001164618
NM_001164619
NM_004484
NP_001158089
NP_001158090
NP_001158091
NP_004475
PF01153
PH_hs_0006599
TC0X001378.hg
uc004exe.4
uc010nrn.4
uc010nro.4
UPI0000032F5E
UPI0000EE62D2
UPI00015E044A
Z37987_s_at
Participant Of
hasMember
HS(1)-PGs [Golgi lumen]
Other forms of this molecule
p-GPC3 [endoplasmic reticulum lumen]
GPC3 [endoplasmic reticulum lumen]
GPC3(25-?) [plasma membrane]
GPC3(25-?) [lysosomal lumen]
HS(6)-GPC3 [lysosomal lumen]
HS(5)-GPC3 [plasma membrane]
HS(3)-GPC3 [plasma membrane]
HS(1)-GPC3 [plasma membrane]
HS(2)-GPC3 [plasma membrane]
HS(6)-GPC3 [plasma membrane]
HS(4)-GPC3 [plasma membrane]
HS(6)-GPC3 [Golgi lumen]
HS(5)-GPC3 [Golgi lumen]
XylS-GPC3(25-?) [Golgi lumen]
Gal-Xyl-GPC3 [Golgi lumen]
GPC3(25-?) [Golgi lumen]
Gal-Gal-Xyl-GPC3 [Golgi lumen]
GlcA-Gal-Gal-Xyl-GPC3 [Golgi lumen]
HS(3)-GPC3 [Golgi lumen]
HS(4)-GPC3 [Golgi lumen]
HS(2)-GPC3 [Golgi lumen]
Heparan(4)-GPC3 [Golgi lumen]
Heparan(3)-GPC3 [Golgi lumen]
Heparan(2)-GPC3 [Golgi lumen]
Heparan(1)-GPC3 [Golgi lumen]
Heparan-GPC3 [Golgi lumen]
Inferred To
HS(1)-Gpc3 [Golgi lumen] (Mus musculus)
Homologues of HS(1)-GPC3 [Golgi lumen] (Danio rerio)
Homologues of HS(1)-GPC3 [Golgi lumen] (Sus scrofa)
Homologues of HS(1)-GPC3 [Golgi lumen] (Xenopus tropicalis)
HS(1)-GPC3 [Golgi lumen] (Bos taurus)
HS(1)-GPC3 [Golgi lumen] (Canis familiaris)
HS(1)-GPC3 [Golgi lumen] (Danio rerio)
HS(1)-GPC3 [Golgi lumen] (Drosophila melanogaster)
HS(1)-GPC3 [Golgi lumen] (Gallus gallus)
HS(1)-GPC3 [Golgi lumen] (Rattus norvegicus)
HS(1)-GPC3 [Golgi lumen] (Sus scrofa)
HS(1)-GPC3 [Golgi lumen] (Taeniopygia guttata)
HS(1)-GPC3 [Golgi lumen] (Xenopus tropicalis)
Modified Residues
Name
O-xylosyl-L-serine (ChEBI:63652) at unknown position
Modification
beta-D-GlcA-(1->4)-alpha-D-GlcNS-(1->4)-beta-D-GlcA-(1->4)-alpha-D-GlcNS-(1->4)-beta-D-GlcA-(1->3)-beta-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-Xyl-yl group
PsiMod Name
O-xylosyl-L-serine
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O3-xylosylserine.
Cross References
RefSeq
NP_004475.1
,
NP_001158091.1
,
NP_001158089.1
GeneCards
P51654
PRO
P51654
Orphanet
16160
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