p-8Y-FGFR2c A314D [plasma membrane]

Stable Identifier
R-HSA-2071946
Type
Genes and Transcripts [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
p-8Y-FGFR2c A314D, p-8Y-FGFR2-1 A314D
Icon
p-8Y-FGFR2c A314D [plasma membrane] icon
p-8Y-FGFR2c A314D [plasma membrane] icon
Locations in the PathwayBrowser
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External Reference Information
External Reference
UniProt:P21802-1 FGFR2
Gene Names
FGFR2, BEK, KGFR, KSAM
Other Identifiers
1143_s_at
1144_at
1145_g_at
11739249_a_at
11740159_x_at
11740394_a_at
11740395_a_at
11740409_a_at
11751508_a_at
11752116_a_at
11753370_s_at
11762105_at
11762745_x_at
11762987_x_at
1363_at
16719025
1970_s_at
203638_PM_s_at
203638_s_at
203639_PM_s_at
203639_s_at
208225_PM_at
208225_at
208228_PM_s_at
208228_s_at
208234_PM_x_at
208234_x_at
211401_PM_s_at
211401_s_at
2263
3310109
3310110
3310111
3310112
3310113
3310118
3310120
3310123
3310125
3310126
3310128
3310129
3310132
3310133
3310137
3310142
3310143
3310144
3310146
3310147
3310149
3310150
3310164
3310165
3310166
3310168
3310173
3310174
3310176
3310178
3310203
3310204
3310205
3310206
3310207
3310208
3310209
3310210
3310211
34354_at
73572_at
7936734
A_23_P303145
A_23_P303149
A_24_P206624
GE61433
GE798271
GO:0000122
GO:0000166
GO:0001525
GO:0001657
GO:0001701
GO:0001837
GO:0002053
GO:0003148
GO:0003149
GO:0003416
GO:0003824
GO:0004672
GO:0004713
GO:0004714
GO:0005007
GO:0005515
GO:0005524
GO:0005576
GO:0005634
GO:0005737
GO:0005794
GO:0005886
GO:0005938
GO:0006351
GO:0006355
GO:0006468
GO:0006915
GO:0007169
GO:0007267
GO:0007409
GO:0008201
GO:0008284
GO:0008543
GO:0008589
GO:0009791
GO:0009880
GO:0009887
GO:0009986
GO:0010518
GO:0010839
GO:0012501
GO:0016020
GO:0016301
GO:0016310
GO:0016331
GO:0016740
GO:0017134
GO:0018108
GO:0021769
GO:0021847
GO:0021860
GO:0022414
GO:0022612
GO:0023052
GO:0030154
GO:0030177
GO:0030282
GO:0030312
GO:0030324
GO:0030855
GO:0030901
GO:0030916
GO:0031012
GO:0031069
GO:0031410
GO:0031982
GO:0032496
GO:0032808
GO:0033688
GO:0035265
GO:0035602
GO:0035603
GO:0035604
GO:0035607
GO:0036211
GO:0042472
GO:0042476
GO:0042802
GO:0042803
GO:0043226
GO:0043235
GO:0043410
GO:0044344
GO:0045165
GO:0045471
GO:0045667
GO:0045787
GO:0045944
GO:0046777
GO:0048286
GO:0048333
GO:0048557
GO:0048562
GO:0048565
GO:0048568
GO:0048608
GO:0048701
GO:0048705
GO:0048730
GO:0048755
GO:0048762
GO:0048856
GO:0050679
GO:0050680
GO:0051150
GO:0051781
GO:0055010
GO:0060045
GO:0060076
GO:0060089
GO:0060174
GO:0060348
GO:0060349
GO:0060442
GO:0060445
GO:0060449
GO:0060463
GO:0060484
GO:0060501
GO:0060512
GO:0060523
GO:0060527
GO:0060529
GO:0060595
GO:0060601
GO:0060615
GO:0060664
GO:0060667
GO:0060670
GO:0060688
GO:0060915
GO:0060916
GO:0062023
GO:0070372
GO:0070374
GO:0071300
GO:0071456
GO:0071560
GO:0090263
GO:0140096
GO:1904707
HMNXSV003001516
HMNXSV003003698
HMNXSV003045562
HMNXSV003050281
ILMN_1682270
M87770_at
PH_hs_0024624
TC10001711.hg
g13186252_3p_a_at
g13186256_3p_at
g13186266_3p_a_at
g186740_3p_a_at
g186781_3p_a_at
g6691454_3p_a_at
g6691454_3p_x_at
Participates
as a component of
Other forms of this molecule
FGFR2c S252W [plasma membrane]
FGFR2c P253R [plasma membrane]
FGFR2c A315S [plasma membrane]
FGFR2c A314S [plasma membrane]
FGFR2c A314D [plasma membrane]
FGFR2c A315T [plasma membrane]
FGFR2c W290G [plasma membrane]
FGFR2c Y375C [plasma membrane]
FGFR2c S372C [plasma membrane]
p-8Y-FGFR2c S252W [plasma membrane]
p-8Y-FGFR2c P253R [plasma membrane]
p-8Y-FGFR2c A315S mutant [plasma membrane]
p-8Y-FGFR2c A314S [plasma membrane]
p-8Y-FGFR2c A315T [plasma membrane]
p-8Y-FGFR2c W290G [plasma membrane]
p-8Y-FGFR2c S372C [plasma membrane]
p-8Y-FGFR2c Y375C [plasma membrane]
FGFR2c long [plasma membrane]
p-8Y-FGFR2c long [plasma membrane]
Modified Residues
Name
O4'-phospho-L-tyrosine at 466
Coordinate
466
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 586
Coordinate
586
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 588
Coordinate
588
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 656
Coordinate
656
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 657
Coordinate
657
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 733
Coordinate
733
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 769
Coordinate
769
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 779
Coordinate
779
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
L-alanine 314 replaced with L-aspartic acid
Coordinate
314
PsiMod
L-aspartic acid residue [MOD:00013]
A protein modification that effectively converts a source amino acid residue to an L-aspartic acid.
L-alanine removal [MOD:01631]
A protein modification that effectively removes or replaces an L-alanine.
Disease
Name Identifier Synonyms
female reproductive endometrioid cancer DOID:3001 endometrioid tumor (morphologic abnormality), endometrioid neoplasm
cancer DOID:162 malignant tumor, malignant neoplasm, primary cancer
Cross References
RefSeq
ZINC - World Drugs
Guide to Pharmacology - Targets
OpenTargets
ZINC - FDA approved
ZINC - Substances
ZINC target
ZINC - Biogenic
PRO
PDB
ZINC - Investigational
COSMIC
IntEnz
HPA
GeneCards
Ensembl
Pharos - Targets
Orphanet
ZINC - Predictions - Purchasable
Interactors (30)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:P09038 FGF2  1 0.779 5
 UniProt:P51812 RPS6KA3  7 0.745 5
 UniProt:P62993 GRB2  1 0.735 6
 ChEBI:73280 SSR      0.683 8
 UniProt:P05230 FGF1  1 0.675 3
 UniProt:P11362 FGFR1  9 0.623 3
 UniProt:O15520 FGF10  1 0.571 2
 UniProt:P19174 PLCG1  6 0.528 3
 UniProt:Q3MIR4 CC50B      0.527 2
 UniProt:O60637 TSN3      0.527 2
 UniProt:Q96LL9 DJC30      0.527 2
 UniProt:Q6P047 CH074      0.527 2
 UniProt:Q99732 LITAF      0.527 2
 UniProt:Q8N7X8 SIGL1      0.527 2
 UniProt:Q5T9A4 ATAD3B  3 0.527 2
 UniProt:Q96HB5 CC120      0.527 2
 UniProt:Q8IWX8 CHERP  1 0.527 2
 UniProt:Q92551 IP6K1  2 0.527 2
 UniProt:Q6P995 F171B      0.527 2
 UniProt:Q92575 UBXN4      0.527 2
 UniProt:Q96L94 SNX22      0.527 2
 UniProt:P01033 TIMP1  4 0.527 2
 UniProt:Q96G30 MRAP2      0.527 2
 UniProt:P55899 FCGRN      0.527 2
 UniProt:Q5TF58 IFFO2      0.527 2
 UniProt:P34741 SDC2  20 0.527 2
 UniProt:Q06124 PTPN11  4 0.519 2
 UniProt:Q9ULH0 KIDINS220  2 0.483 2
 UniProt:Q9UBH6 S53A1      0.483 2
 UniProt:Q86VI4 LAP4B      0.463 2
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