p-8Y-FGFR2c A315S mutant [plasma membrane]

Stable Identifier
R-HSA-2071942
Type
Genes and Transcripts [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
p-8Y-FGFR2-1 A315S mutant
Icon
p-8Y-FGFR2c A315S mutant [plasma membrane] icon
p-8Y-FGFR2c A315S mutant [plasma membrane] icon
Locations in the PathwayBrowser
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External Reference Information
External Reference
UniProt:P21802-1 FGFR2
Gene Names
FGFR2, BEK, KGFR, KSAM
Participates
as a component of
Other forms of this molecule
FGFR2c S252W [plasma membrane]
FGFR2c P253R [plasma membrane]
FGFR2c A315S [plasma membrane]
FGFR2c A314S [plasma membrane]
FGFR2c A314D [plasma membrane]
FGFR2c A315T [plasma membrane]
FGFR2c W290G [plasma membrane]
FGFR2c Y375C [plasma membrane]
FGFR2c S372C [plasma membrane]
p-8Y-FGFR2c S252W [plasma membrane]
p-8Y-FGFR2c P253R [plasma membrane]
p-8Y-FGFR2c A314S [plasma membrane]
p-8Y-FGFR2c A314D [plasma membrane]
p-8Y-FGFR2c A315T [plasma membrane]
p-8Y-FGFR2c W290G [plasma membrane]
p-8Y-FGFR2c S372C [plasma membrane]
p-8Y-FGFR2c Y375C [plasma membrane]
FGFR2c long [plasma membrane]
p-8Y-FGFR2c long [plasma membrane]
Modified Residues
Name
O4'-phospho-L-tyrosine at 466
Coordinate
466
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 586
Coordinate
586
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 588
Coordinate
588
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 656
Coordinate
656
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 657
Coordinate
657
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 733
Coordinate
733
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 769
Coordinate
769
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 779
Coordinate
779
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
L-alanine 315 replaced with L-serine
Coordinate
315
PsiMod
L-serine residue [MOD:00025]
A protein modification that effectively converts a source amino acid residue to L-serine.
L-alanine removal [MOD:01631]
A protein modification that effectively removes or replaces an L-alanine.
Disease
Name Identifier Synonyms
bone development disease DOID:0080006
syndactyly DOID:11193 Symphalangism, Symphalangy (disorder), (Polysyndactyly) or (symphalangism) or (syndactyly NOS), Webbing of digits
Interactors (30)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:P09038 FGF2  1 0.779 5
 UniProt:P51812 RPS6KA3  7 0.745 5
 UniProt:P62993 GRB2  1 0.735 6
 ChEBI:73280 SSR      0.683 8
 UniProt:P05230 FGF1  1 0.675 3
 UniProt:P11362 FGFR1  9 0.623 3
 UniProt:O15520 FGF10  1 0.571 2
 UniProt:P19174 PLCG1  6 0.528 3
 UniProt:Q3MIR4 CC50B      0.527 2
 UniProt:O60637 TSN3      0.527 2
 UniProt:Q96LL9 DJC30      0.527 2
 UniProt:Q6P047 CH074      0.527 2
 UniProt:Q99732 LITAF      0.527 2
 UniProt:Q8N7X8 SIGL1      0.527 2
 UniProt:Q5T9A4 ATAD3B  3 0.527 2
 UniProt:Q96HB5 CC120      0.527 2
 UniProt:Q8IWX8 CHERP  1 0.527 2
 UniProt:Q92551 IP6K1  2 0.527 2
 UniProt:Q6P995 F171B      0.527 2
 UniProt:P34741 SDC2  20 0.527 2
 UniProt:Q92575 UBXN4      0.527 2
 UniProt:Q96L94 SNX22      0.527 2
 UniProt:P01033 TIMP1  4 0.527 2
 UniProt:Q96G30 MRAP2      0.527 2
 UniProt:P55899 FCGRN      0.527 2
 UniProt:Q5TF58 IFFO2      0.527 2
 UniProt:Q06124 PTPN11  4 0.519 2
 UniProt:Q9ULH0 KIDINS220  2 0.483 2
 UniProt:Q9UBH6 S53A1      0.483 2
 UniProt:Q86VI4 LAP4B      0.463 2
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