The final step in the beta-oxidation process is the thiolytic cleavage of 1-(3-oxo-6Z,9Z,12Z,15Z,18Z,21Z-tetracosahexaenoyl)-CoA to form docosahexaenoyl-CoA (DHA-CoA). This step is catalysed by both sterol carrier protein X (SCPx) and the classic 3-ketoacyl-CoA thiolase (this reaction) (Ferdinandusse et al. 2001).
Hurt, E, Sprecher, H, Yoder, E, Moore, SA, Spector, AA
Denis, S, Mooijer, PA, Wanders, RJA, Zhang, Z, Reddy, JK, Spector, AA, Ferdinandusse, S
acetate CoA-transferase activity of ACAA1 [peroxisomal matrix]
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