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FGFR2c mutant dimers with enhanced ligand-binding [plasma membrane]
Stable Identifier
R-HSA-2065983
Type
Set [CandidateSet]
Species
Homo sapiens
Compartment
plasma membrane
Locations in the PathwayBrowser
Expand all
Disease (Homo sapiens)
Diseases of signal transduction by growth factor receptors and second messengers (Homo sapiens)
Signaling by FGFR in disease (Homo sapiens)
Signaling by FGFR2 in disease (Homo sapiens)
FGFR2 mutant receptor activation (Homo sapiens)
Activated point mutants of FGFR2 (Homo sapiens)
Autocatalytic phosphorylation of FGFR2c mutants with enhanced ligand binding (Homo sapiens)
FGFR2c mutant dimers with enhanced ligand-binding bound to FGFs [plasma membrane] (Homo sapiens)
FGFR2c mutant dimers with enhanced ligand-binding [plasma membrane] (Homo sapiens)
FGFR2c mutants bind an expanded range of ligands (Homo sapiens)
FGFR2c mutant dimers with enhanced ligand-binding bound to FGFs [plasma membrane] (Homo sapiens)
FGFR2c mutant dimers with enhanced ligand-binding [plasma membrane] (Homo sapiens)
Point mutants of FGFR2 bind and are inactivated by tyrosine kinase inhibitors (Homo sapiens)
FGFR2 point mutant dimers [plasma membrane] (Homo sapiens)
FGFR2c mutant dimers with enhanced ligand-binding bound to FGFs [plasma membrane] (Homo sapiens)
FGFR2c mutant dimers with enhanced ligand-binding [plasma membrane] (Homo sapiens)
FGFR2 point mutant dimers:TKIs [plasma membrane] (Homo sapiens)
FGFR2 point mutant dimers [plasma membrane] (Homo sapiens)
FGFR2c mutant dimers with enhanced ligand-binding bound to FGFs [plasma membrane] (Homo sapiens)
FGFR2c mutant dimers with enhanced ligand-binding [plasma membrane] (Homo sapiens)
Participants
members
FGFR2c S252W mutant dimer [plasma membrane]
(Homo sapiens)
FGFR2c P253R mutant dimer [plasma membrane]
(Homo sapiens)
FGFR2c A315S mutant dimer [plasma membrane]
(Homo sapiens)
candidates
FGFR2c A314S mutant dimer [plasma membrane]
(Homo sapiens)
FGFR2c A314D mutant dimer [plasma membrane]
(Homo sapiens)
FGFR2c A315T mutant dimer [plasma membrane]
(Homo sapiens)
Participates
as a component of
FGFR2c mutant dimers with enhanced ligand-binding bound to FGFs [plasma membrane] (Homo sapiens)
Disease
Name
Identifier
Synonyms
cancer
DOID:162
malignant tumor, malignant neoplasm, primary cancer
bone development disease
DOID:0080006
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