YAP1 binds ZO-2 (TJP2)

Stable Identifier
R-HSA-2064421
Type
Reaction [binding]
Species
Homo sapiens
Compartment
cytosol
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YAP1 binds ZO-2 (TJP2)
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Cytosolic ZO-2 (TJP2) binds YAP1 to form a complex (Oka et al. 2010). The phosphorylation state of the YAP1 protein involved in this interaction has not been determined experimentally; it is inferred to be unphosphorylated.

Literature References
PubMed ID Title Journal Year
20868367 Functional complexes between YAP2 and ZO-2 are PDZ domain-dependent, and regulate YAP2 nuclear localization and signalling

Meerschaert, K, Bader, GD, Vandekerckhove, J, Remue, E, Gettemans, J, Sudol, M, Vanloo, B, Boucherie, C, Oka, T, Gfeller, D, Sidhu, SS

Biochem J 2010
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Orthologous Events
YAP1 binds ZO-2 (TJP2) (Bos taurus)
YAP1 binds ZO-2 (TJP2) (Caenorhabditis elegans)
YAP1 binds ZO-2 (TJP2) (Danio rerio)
YAP1 binds ZO-2 (TJP2) (Gallus gallus)
YAP1 binds ZO-2 (TJP2) (Mus musculus)
YAP1 binds ZO-2 (TJP2) (Rattus norvegicus)
YAP1 binds ZO-2 (TJP2) (Sus scrofa)
YAP1 binds ZO-2 (TJP2) (Xenopus tropicalis)
Authored
D'Eustachio, P  (2012-02-03)
Reviewed
Sudol, M  (2012-02-03)
Created
D'Eustachio, P  (2012-01-19)
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