NRAGE activates JNK

Stable Identifier
R-HSA-205132
Type
Reaction [transition]
Species
Homo sapiens
Compartment
cytosol, plasma membrane
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NRAGE activates JNK
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The NGF:p75:NRAGE complex promotes threonine and tyrosine phosphorylation, and activation of JNK, by an unknown mechanism.

Participants
Input
Output
Participant Of
hasEvent
Catalyst Activity
Catalyst Activity
Title
JUN kinase activity of NGF:p75NTR:NRAGE [plasma membrane]
Physical Entity
NGF:p75NTR:NRAGE [plasma membrane]
Activity
JUN kinase activity (0004705)
Inferred From
Nrage activates Jnk1 (Rattus norvegicus)
Authored
Nasi, S  (2006-10-10)
Annibali, D  (2006-10-10)
Reviewed
Friedman, WJ  (2008-05-20)
Chao, MV  (2008-05-28)
Created
Jassal, B  (2007-12-06)