NADE protein (p75NTR-associated cell death executor) may induce cell death upon NGF binding, but not BDNF, NT3, or NT4/5 binding, to p75NTR. The NADE-dependent apoptosis is modulated by the 14-3-3-epsilon protein (Kimura MT et al, 2001).
Irie, S, Sato, TA, Mukai, J, Shoji-Hoshino, S, Oshimura, M, Nadano, D, Kimura, MT
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