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NGF ligand:p75NTR:NRIF:TRAF6 [plasma membrane]
Stable Identifier
R-HSA-204977
Type
Complex
Species
Homo sapiens
Compartment
plasma membrane
Locations in the PathwayBrowser
Expand all
Signal Transduction (Homo sapiens)
Death Receptor Signalling (Homo sapiens)
p75 NTR receptor-mediated signalling (Homo sapiens)
Cell death signalling via NRAGE, NRIF and NADE (Homo sapiens)
NRIF signals cell death from the nucleus (Homo sapiens)
NRIF and TRAF6 may activate JNK (Homo sapiens)
NGF ligand:p75NTR:NRIF:TRAF6 [plasma membrane] (Homo sapiens)
TRAF6 binds to p75NTR:NRIF (Homo sapiens)
NGF ligand:p75NTR:NRIF:TRAF6 [plasma membrane] (Homo sapiens)
gamma-secretase cleaves p75NTR, releasing NRIF and TRAF6 (Homo sapiens)
NGF ligand:p75NTR:NRIF:TRAF6 [plasma membrane] (Homo sapiens)
Participants
components
NGF ligand:p75NTR:NRIF [plasma membrane] (Homo sapiens)
TRAF6 homotrimer [cytosol] (Homo sapiens)
Participant Of
input
gamma-secretase cleaves p75NTR, releasing NRIF and TRAF6
output
TRAF6 binds to p75NTR:NRIF
Inferred To
NGF ligand:p75NTR:NRIF:TRAF6 [plasma membrane] (Bos taurus)
NGF ligand:p75NTR:NRIF:TRAF6 [plasma membrane] (Canis familiaris)
NGF ligand:p75NTR:NRIF:TRAF6 [plasma membrane] (Danio rerio)
NGF ligand:p75NTR:NRIF:TRAF6 [plasma membrane] (Gallus gallus)
NGF ligand:p75NTR:NRIF:TRAF6 [plasma membrane] (Mus musculus)
NGF ligand:p75NTR:NRIF:TRAF6 [plasma membrane] (Rattus norvegicus)
NGF ligand:p75NTR:NRIF:TRAF6 [plasma membrane] (Sus scrofa)
NGF ligand:p75NTR:NRIF:TRAF6 [plasma membrane] (Taeniopygia guttata)
NGF ligand:p75NTR:NRIF:TRAF6 [plasma membrane] (Xenopus tropicalis)
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