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Gal-glycan LUM [Golgi lumen]
Stable Identifier
R-HSA-2046248
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
Golgi lumen
Synonyms
Lumican, LUM_HUMAN, LUM
Locations in the PathwayBrowser
Expand all
Metabolism (Homo sapiens)
Metabolism of carbohydrates (Homo sapiens)
Glycosaminoglycan metabolism (Homo sapiens)
Keratan sulfate/keratin metabolism (Homo sapiens)
Keratan sulfate biosynthesis (Homo sapiens)
B3GNT1,2,3,4,7 add GlcNAc to form Keratan-PG (Homo sapiens)
Gal-glycan-protein [Golgi lumen] (Homo sapiens)
Gal-glycan LUM [Golgi lumen] (Homo sapiens)
B4GALTs transfer Gal to the N-glycan precursor (Homo sapiens)
Gal-glycan-protein [Golgi lumen] (Homo sapiens)
Gal-glycan LUM [Golgi lumen] (Homo sapiens)
External Reference Information
External Reference
UniProt:P51884 LUM
Gene Names
LUM, LDC, SLRR2D
Chain
signal peptide:1-18, chain:19-338
Reference Genes
BioGPS Gene:4060 LUM
COSMIC (genes):LUM LUM
CTD Gene:4060 LUM
dbSNP Gene:4060 LUM
ENSEMBL:ENSG00000139329 LUM
ENSEMBL_homo_sapiens_GENE:ENSG00000139329 LUM
HGNC:6724 LUM
KEGG Gene (Homo sapiens):4060 LUM
Monarch:4060 LUM
NCBI Gene:4060 LUM
OMIM:600616 LUM
UCSC:P51884 LUM
Reference Transcript
RefSeq:NM_002345.3 LUM
Other Identifiers
0006650242
11715796_s_at
1522
16768406
201744_s_at
229554_at
25783
3465249
3465250
3465251
3465252
3465253
3465254
3465257
3465258
3465259
3465260
3465261
38038_at
4060
52570_at
7965403
A_23_P99063
A_24_P270279
AAA85268
AAA91639
AAH07038
AAH35997
AAP35353
AK312682
BAG35562
BC007038
BC035997
BT006707
CAB025783
CCDS9038
CH471054
EAW97449
ENSG00000139329
ENSP00000266718
ENST00000266718
EntrezGene:4060
g4505046_3p_a_at
GE79985
GE88676
GO:0003674
GO:0005198
GO:0005201
GO:0005515
GO:0005518
GO:0005575
GO:0005576
GO:0005583
GO:0005615
GO:0005622
GO:0005623
GO:0005737
GO:0005764
GO:0005773
GO:0005794
GO:0005796
GO:0006790
GO:0007601
GO:0008150
GO:0009056
GO:0009058
GO:0014070
GO:0018146
GO:0030021
GO:0030198
GO:0030199
GO:0031012
GO:0032914
GO:0032991
GO:0034641
GO:0042340
GO:0043202
GO:0043226
GO:0044281
GO:0045944
GO:0048856
GO:0050877
GO:0051216
GO:0062023
GO:0070062
GO:0070848
HGNC:6724
HPA001522
Hs.79914.1.A1_3p_at
ILMN_1790529
ILMN_2167805
IPR000372
IPR001611
IPR003591
IPR027219
IPR032675
LUM
LUM-201
MIM:600616
NM_002345
NP_002336
PF01462
PF13516
PF13855
PH_hs_0024678
PH_hs_0040682
PR00019
SM00013
SM00364
SM00365
SM00369
TC12001803.hg
U18728
U21128
U21128_at
uc001tbm.4
UPI0000001C4D
Participant Of
hasMember
Gal-glycan-protein [Golgi lumen]
Other forms of this molecule
LUM [lysosomal lumen]
KS(2)-LUM [lysosomal lumen]
KS(2)-LUM [extracellular region]
N-glycan LUM [Golgi lumen]
Keratan(1)-LUM [Golgi lumen]
Keratan(2)-LUM [Golgi lumen]
Keratan(3)-LUM [Golgi lumen]
Keratan(4)-LUM [Golgi lumen]
KS(2)-LUM [Golgi lumen]
KS(1)-LUM [Golgi lumen]
LUM [extracellular region]
Inferred To
Gal-glycan LUM [Golgi lumen] (Bos taurus)
Gal-glycan LUM [Golgi lumen] (Canis familiaris)
Gal-glycan LUM [Golgi lumen] (Danio rerio)
Gal-glycan LUM [Golgi lumen] (Gallus gallus)
Gal-glycan LUM [Golgi lumen] (Mus musculus)
Gal-glycan LUM [Golgi lumen] (Rattus norvegicus)
Gal-glycan LUM [Golgi lumen] (Sus scrofa)
Gal-glycan LUM [Golgi lumen] (Taeniopygia guttata)
Gal-glycan LUM [Golgi lumen] (Xenopus tropicalis)
Homologues of Gal-glycan LUM [Golgi lumen] (Danio rerio)
Modified Residues
Name
N4-(N-acetylamino)glucosyl-L-asparagine (ChEBI:63492) at unknown position
Modification
beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->3)-[beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAcl-(1->4)-beta-D-GlcNAc-yl group
PsiMod Name
N4-(N-acetylamino)glucosyl-L-asparagine
PsiMod Definition
A protein modification that effectively converts an L-asparagine residue to N4-(N-acetylaminoglucosyl)-L-asparagine.
Cross References
RefSeq
NP_002336.1
OpenTargets
ENSG00000139329
GeneCards
P51884
PRO
P51884
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P50281 MMP14
3
MMP14(21-582) [Golgi lumen]
(R-HSA-1604689)
MMP14 [plasma membrane]
(R-HSA-1442472)
MMP14 [Golgi lumen]
(R-HSA-1604724)
0.558
2
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