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KS(2)-KERA [extracellular region]
Stable Identifier
R-HSA-2046192
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
extracellular region
Synonyms
Keratocan, KERA_HUMAN, KERA
Locations in the PathwayBrowser
Expand all
Metabolism (Homo sapiens)
Metabolism of carbohydrates (Homo sapiens)
Glycosaminoglycan metabolism (Homo sapiens)
Keratan sulfate/keratin metabolism (Homo sapiens)
Keratan sulfate biosynthesis (Homo sapiens)
KSPG is secreted from the cell (Homo sapiens)
KSPG(2) [extracellular region] (Homo sapiens)
KS(2)-KERA [extracellular region] (Homo sapiens)
Keratan sulfate degradation (Homo sapiens)
Extracellular KSPG translocates to the lysosome for degradation (Homo sapiens)
KSPG(2) [extracellular region] (Homo sapiens)
KS(2)-KERA [extracellular region] (Homo sapiens)
External Reference Information
External Reference
UniProt:O60938 KERA
Gene Names
KERA, SLRR2B
Chain
signal peptide:1-20, chain:21-352
Reference Genes
BioGPS Gene:11081 KERA
COSMIC (genes):KERA KERA
CTD Gene:11081 KERA
dbSNP Gene:11081 KERA
ENSEMBL:ENSG00000139330 KERA
HGNC:6309 KERA
KEGG:hsa:11081 KERA
Monarch:11081 KERA
NCBI Gene:11081 KERA
OMIM:603288 KERA
UCSC:O60938 KERA
Reference Transcript
RefSeq:NM_007035.3 KERA
Other Identifiers
11081
11728031_at
16768401
220504_PM_at
220504_at
3465228
3465229
3465230
3465233
3465234
3465235
7965398
81884_r_at
A_24_P261750
GE58431
GO:0003674
GO:0005515
GO:0005576
GO:0005615
GO:0005796
GO:0007601
GO:0030312
GO:0031012
GO:0043202
GO:0048856
GO:0050877
GO:0061303
HMNXSV003026649
ILMN_1732678
ILMN_2151304
PH_hs_0007122
TC12001802.hg
g8659566_3p_at
Participates
as a member of
KSPG(2) [extracellular region] (Homo sapiens)
Other forms of this molecule
N-glycan KERA [Golgi lumen]
Gal-glycan KERA [Golgi lumen]
Keratan(1)-KERA [Golgi lumen]
Keratan(2)-KERA [Golgi lumen]
Keratan(3)-KERA [Golgi lumen]
Keratan(4)-KERA [Golgi lumen]
KS(2)-KERA [Golgi lumen]
KS(1)-KERA [Golgi lumen]
KERA [lysosomal lumen]
KS(2)-KERA [lysosomal lumen]
Inferred To
Kera [extracellular region]
(Mus musculus)
Kera [extracellular region]
(Rattus norvegicus)
Dmel\CG32055 [extracellular region]
(Drosophila melanogaster)
KERA [extracellular region]
(Bos taurus)
KERA [extracellular region]
(Canis familiaris)
KERA [extracellular region]
(Gallus gallus)
KERA [extracellular region]
(Sus scrofa)
kera [extracellular region]
(Danio rerio)
Modified Residues
Name
N4-(N-acetylamino)glucosyl-L-asparagine (ChEBI:63520) at unknown position
Modification
alpha-NeuNAc-(2->3)-beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->3)-[beta-D-Gal6S-(1->4)-beta-D-GlcNAc6S-(1->3)-beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc-yl group
PsiMod Name
N4-(N-acetylamino)glucosyl-L-asparagine
PsiMod Definition
A protein modification that effectively converts an L-asparagine residue to N4-(N-acetylaminoglucosyl)-L-asparagine.
Cross References
ENSEMBL
ENSP00000266719
,
ENST00000266719
OpenTargets
ENSG00000139330
HPA
ENSG00000139330-KERA
PRO
O60938
Pharos - Targets
O60938
GlyGen
O60938
Orphanet
KERA
HMDB Protein
HMDBP02315
Interactors (2)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q9BQG2 NUDT12
1
NUDT12 [peroxisomal matrix]
(R-HSA-6809221)
0.527
2
UniProt:P41743 PRKCI
3
PRKCI [nucleoplasm]
(R-HSA-9021345)
PRKCI [cytosol]
(R-HSA-58206)
PRKCI [plasma membrane]
(R-HSA-420005)
0.527
2
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