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KSPG is secreted from the cell
Stable Identifier
R-HSA-2046180
Type
Reaction [omitted]
Species
Homo sapiens
Compartment
Golgi lumen
,
extracellular region
ReviewStatus
5/5
Locations in the PathwayBrowser
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Metabolism (Homo sapiens)
Metabolism of carbohydrates (Homo sapiens)
Glycosaminoglycan metabolism (Homo sapiens)
Keratan sulfate/keratin metabolism (Homo sapiens)
Keratan sulfate biosynthesis (Homo sapiens)
KSPG is secreted from the cell (Homo sapiens)
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The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
Once formed, keratan sulfate proteoglycans (KSPGs) are secreted from the cell into the extracellular matrix (ECM) by an unknown translocation mechanism (Funderburgh 2000). KSPG can bind with many cell surface and extracellular proteins.
Literature References
PubMed ID
Title
Journal
Year
11030741
Keratan sulfate: structure, biosynthesis, and function
Funderburgh, JL
Glycobiology
2000
Participants
Input
KSPG(2) [Golgi lumen]
(Homo sapiens)
Output
KSPG(2) [extracellular region]
(Homo sapiens)
Participates
as an event of
Keratan sulfate biosynthesis (Homo sapiens)
Orthologous Events
KSPG is secreted from the cell (Bos taurus)
KSPG is secreted from the cell (Canis familiaris)
KSPG is secreted from the cell (Danio rerio)
KSPG is secreted from the cell (Drosophila melanogaster)
KSPG is secreted from the cell (Gallus gallus)
KSPG is secreted from the cell (Mus musculus)
KSPG is secreted from the cell (Rattus norvegicus)
KSPG is secreted from the cell (Sus scrofa)
KSPG is secreted from the cell (Xenopus tropicalis)
Authored
Jassal, B (2011-12-01)
Reviewed
D'Eustachio, P (2012-03-28)
Created
Jassal, B (2012-01-11)
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