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Keratan(4)-OGN [Golgi lumen]
Stable Identifier
R-HSA-2046142
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
Golgi lumen
Synonyms
Mimecan, Osteoglycin, MIME_HUMAN, OGN
Locations in the PathwayBrowser
Expand all
Disease (Homo sapiens)
Diseases of metabolism (Homo sapiens)
Diseases of glycosylation (Homo sapiens)
Diseases associated with glycosaminoglycan metabolism (Homo sapiens)
Defective CHST6 causes MCDC1 (Homo sapiens)
Defective CHST6 does not transfer SO4(2-) to GlcNAc residues on keratan-PG (Homo sapiens)
Keratan(4)-PG [Golgi lumen] (Homo sapiens)
Keratan(4)-OGN [Golgi lumen] (Homo sapiens)
Metabolism (Homo sapiens)
Metabolism of carbohydrates (Homo sapiens)
Glycosaminoglycan metabolism (Homo sapiens)
Keratan sulfate/keratin metabolism (Homo sapiens)
Keratan sulfate biosynthesis (Homo sapiens)
CHST2,5,6 transfer SO4(2-) to GlcNAc residues on keratan-PG to form KSPG (Homo sapiens)
Keratan(4)-PG [Golgi lumen] (Homo sapiens)
Keratan(4)-OGN [Golgi lumen] (Homo sapiens)
The keratan chain can be capped by N-acetylneuraminic acid (Homo sapiens)
Keratan(4)-PG [Golgi lumen] (Homo sapiens)
Keratan(4)-OGN [Golgi lumen] (Homo sapiens)
External Reference Information
External Reference
UniProt:P20774 OGN
Gene Names
OGN, OIF, SLRR3A
Chain
signal peptide:1-20, chain:21-298
Reference Genes
BioGPS Gene:4969 OGN
COSMIC (genes):OGN OGN
CTD Gene:4969 OGN
dbSNP Gene:4969 OGN
ENSEMBL:ENSG00000106809 OGN
HGNC:8126 OGN
KEGG:hsa:4969 OGN
Monarch:4969 OGN
NCBI Gene:4969 OGN
OMIM:602383 OGN
UCSC:P20774 OGN
Reference Transcript
RefSeq:NM_033014.3 OGN
RefSeq:NM_024416.4 OGN
RefSeq:NM_014057.4 OGN
Other Identifiers
11736190_a_at
11736191_s_at
11742820_s_at
11742821_s_at
11748546_a_at
17095870
218730_PM_s_at
218730_s_at
222722_PM_at
222722_at
3214799
3214801
3214802
3214803
3214804
3214805
3214806
3214807
3214808
3214809
3214810
3214811
3214813
3214814
3214815
3214816
3214817
3214818
43506_at
43507_g_at
4969
65604_at
8162373
A_23_P82990
A_33_P3279590
GE56609
GO:0005198
GO:0005515
GO:0005576
GO:0005615
GO:0005796
GO:0007165
GO:0008083
GO:0030021
GO:0030312
GO:0031012
GO:0043202
GO:0043226
GO:0048018
GO:0048662
GO:0048856
GO:0060348
GO:0061975
GO:0062023
GO:0070062
GO:0098772
GO:1903561
HMNXSV003003742
Hs.109439.0.S3_3p_at
ILMN_1688838
ILMN_1790098
ILMN_2387105
PH_hs_0006043
TC09001334.hg
g7661703_3p_a_at
Participates
as a member of
Keratan(4)-PG [Golgi lumen] (Homo sapiens)
Other forms of this molecule
N-glycan OGN [Golgi lumen]
Gal-glycan OGN [Golgi lumen]
Keratan(1)-OGN [Golgi lumen]
Keratan(2)-OGN [Golgi lumen]
Keratan(3)-OGN [Golgi lumen]
KS(2)-OGN [Golgi lumen]
KS(1)-OGN [Golgi lumen]
KS(2)-OGN [extracellular region]
OGN [lysosomal lumen]
KS(2)-OGN [lysosomal lumen]
Inferred To
OGN [Golgi lumen]
(Canis familiaris)
OGN [Golgi lumen]
(Gallus gallus)
OGN [Golgi lumen]
(Sus scrofa)
Keratan(4)-OGN [Golgi lumen]
(Bos taurus)
ogna [Golgi lumen]
(Danio rerio)
Ogn [Golgi lumen]
(Mus musculus)
Modified Residues
Name
N4-(N-acetylamino)glucosyl-L-asparagine (ChEBI:63500) at unknown position
Modification
alpha-NeuNAc-(2->3)-beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->3)-[beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc-yl group
PsiMod Name
N4-(N-acetylamino)glucosyl-L-asparagine
PsiMod Definition
A protein modification that effectively converts an L-asparagine residue to N4-(N-acetylaminoglucosyl)-L-asparagine.
Cross References
ENSEMBL
ENSP00000516802
,
ENSP00000516801
,
ENST00000375561
,
ENST00000707237
,
ENST00000707238
,
ENST00000262551
,
ENSP00000364711
,
ENSP00000262551
OpenTargets
ENSG00000106809
HPA
ENSG00000106809-OGN
PRO
P20774
Pharos - Targets
P20774
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q9BT09 CNPY3
1
CNPY3 [endoplasmic reticulum lumen]
(R-HSA-1678932)
0.527
3
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