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SLIT3 [extracellular region]
Stable Identifier
R-HSA-204357
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
extracellular region
Synonyms
Slit homolog 3 protein, SLIT3_HUMAN
Icon
Locations in the PathwayBrowser
Expand all
Developmental Biology (Homo sapiens)
Nervous system development (Homo sapiens)
Axon guidance (Homo sapiens)
Netrin-1 signaling (Homo sapiens)
DCC interaction with ROBO1 (Homo sapiens)
DCC:ROBO1:SLIT [plasma membrane] (Homo sapiens)
ROBO1:SLIT [plasma membrane] (Homo sapiens)
SLIT [extracellular region] (Homo sapiens)
SLIT3 [extracellular region] (Homo sapiens)
ROBO1:SLIT [plasma membrane] (Homo sapiens)
SLIT [extracellular region] (Homo sapiens)
SLIT3 [extracellular region] (Homo sapiens)
Signaling by ROBO receptors (Homo sapiens)
ROBO1,ROBO2 bind SLIT3 (Homo sapiens)
SLIT3 [extracellular region] (Homo sapiens)
SLIT3:ROBO1,ROBO2 [plasma membrane] (Homo sapiens)
ROBO1:SLIT3 [plasma membrane] (Homo sapiens)
SLIT3 [extracellular region] (Homo sapiens)
ROBO2:SLIT3 [plasma membrane] (Homo sapiens)
SLIT3 [extracellular region] (Homo sapiens)
Regulation of commissural axon pathfinding by SLIT and ROBO (Homo sapiens)
DCC interaction with ROBO1 (Homo sapiens)
DCC:ROBO1:SLIT [plasma membrane] (Homo sapiens)
ROBO1:SLIT [plasma membrane] (Homo sapiens)
SLIT [extracellular region] (Homo sapiens)
SLIT3 [extracellular region] (Homo sapiens)
ROBO1:SLIT [plasma membrane] (Homo sapiens)
SLIT [extracellular region] (Homo sapiens)
SLIT3 [extracellular region] (Homo sapiens)
SLITs bind keratan sulfate (Homo sapiens)
SLIT2,(SLIT3) [extracellular region] (Homo sapiens)
SLIT3 [extracellular region] (Homo sapiens)
SLIT2,(SLIT3):Keratan sulfate [extracellular region] (Homo sapiens)
SLIT2,(SLIT3) [extracellular region] (Homo sapiens)
SLIT3 [extracellular region] (Homo sapiens)
External Reference Information
External Reference
UniProt:O75094 SLIT3
Gene Names
SLIT3, KIAA0814, MEGF5, SLIL2, UNQ691/PRO1336
Chain
signal peptide:1-33, chain:34-1523
Reference Genes
BioGPS Gene:6586 SLIT3
COSMIC (genes):SLIT3 SLIT3
CTD Gene:6586 SLIT3
dbSNP Gene:6586 SLIT3
ENSEMBL:ENSG00000184347 SLIT3
HGNC:11087 SLIT3
Monarch:6586 SLIT3
NCBI Gene:6586 SLIT3
OMIM:603745 SLIT3
UCSC:O75094 SLIT3
Reference Transcript
RefSeq:NM_001271946.1 SLIT3
RefSeq:NM_003062.3 SLIT3
Other Identifiers
11727067_a_at
17002612
203812_PM_at
203812_at
203813_PM_s_at
203813_s_at
216216_3p_at
216216_PM_at
216216_at
2886176
2886177
2886178
2886179
2886180
2886181
2886182
2886183
2886184
2886185
2886186
2886187
2886188
2886189
2886190
2886191
2886192
2886196
2886197
2886198
2886199
2886200
2886201
2886202
2886213
2886214
2886218
2886225
2886227
2886228
2886231
2886232
2886234
2886239
2886242
2886243
2886244
2886245
2886246
2886248
2886250
2886263
2886264
2886265
2886273
2886276
2886277
2886278
2886279
2886280
2886284
2886290
2886297
2886299
2886305
2886306
2886307
2886308
2886324
2886358
2886371
2886377
2886378
2886379
2886395
2886396
2886397
2886399
2886401
2886403
35324_at
59822_at
6586
8115691
A_23_P58588
A_24_P911040
A_24_P936232
GE53313
GE626307
GO:0003180
GO:0003181
GO:0005102
GO:0005509
GO:0005515
GO:0005576
GO:0005615
GO:0005739
GO:0007399
GO:0007411
GO:0008201
GO:0008285
GO:0009887
GO:0010629
GO:0012501
GO:0030154
GO:0030308
GO:0032870
GO:0035385
GO:0043226
GO:0048495
GO:0048846
GO:0048856
GO:0050919
GO:0051414
GO:0060412
GO:0061364
GO:0070100
HMNXSV003037353
Hs.57929.0.S2_3p_at
Hs.57929.1.S1_3p_at
Hs.57929.1.S1_3p_x_at
ILMN_1811313
ILMN_1864685
PH_hs_0022423
TC05002043.hg
g11321570_3p_a_at
Participates
as a component of
ROBO1:SLIT3 [plasma membrane] (Homo sapiens)
ROBO2:SLIT3 [plasma membrane] (Homo sapiens)
as an input of
ROBO1,ROBO2 bind SLIT3 (Homo sapiens)
as a member of
SLIT [extracellular region] (Homo sapiens)
as a candidate of
SLIT2,(SLIT3) [extracellular region] (Homo sapiens)
Inferred To
sli [extracellular region]
(Drosophila melanogaster)
SLIT3 [extracellular region]
(Bos taurus)
SLIT3 [extracellular region]
(Canis familiaris)
SLIT3 [extracellular region]
(Gallus gallus)
SLIT3 [extracellular region]
(Sus scrofa)
Slit3 [extracellular region]
(Mus musculus)
slt-1 [extracellular region]
(Caenorhabditis elegans)
Cross References
ENSEMBL
ENSP00000430333
,
ENST00000332966
,
ENSP00000332164
,
ENST00000519560
OpenTargets
ENSG00000184347
HPA
ENSG00000184347-SLIT3
PRO
O75094
Pharos - Targets
O75094
GlyGen
O75094
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