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SEC24D [endoplasmic reticulum membrane]
Stable Identifier
R-HSA-204004
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
endoplasmic reticulum membrane
Synonyms
Protein transport protein Sec24D, S24D_HUMAN
Locations in the PathwayBrowser
Expand all
Immune System (Homo sapiens)
Adaptive Immune System (Homo sapiens)
Class I MHC mediated antigen processing & presentation (Homo sapiens)
Antigen Presentation: Folding, assembly and peptide loading of class I MHC (Homo sapiens)
Budding of COPII coated vesicle (Homo sapiens)
COPII vesicle with MHC class I [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
Sar1p:GTP:Sec23p:Sec24p:Ag bound MHC class I [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
SEC23:SEC24 [endoplasmic reticulum membrane] (Homo sapiens)
SEC24 [endoplasmic reticulum membrane] (Homo sapiens)
SEC24D [endoplasmic reticulum membrane] (Homo sapiens)
Capturing cargo and formation of prebudding complex (Homo sapiens)
SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Homo sapiens)
SEC23:SEC24 [endoplasmic reticulum membrane] (Homo sapiens)
SEC24 [endoplasmic reticulum membrane] (Homo sapiens)
SEC24D [endoplasmic reticulum membrane] (Homo sapiens)
Sar1p:GTP:Sec23p:Sec24p:Ag bound MHC class I [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
SEC23:SEC24 [endoplasmic reticulum membrane] (Homo sapiens)
SEC24 [endoplasmic reticulum membrane] (Homo sapiens)
SEC24D [endoplasmic reticulum membrane] (Homo sapiens)
Coat Assembly (Homo sapiens)
SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Homo sapiens)
SEC23:SEC24 [endoplasmic reticulum membrane] (Homo sapiens)
SEC24 [endoplasmic reticulum membrane] (Homo sapiens)
SEC24D [endoplasmic reticulum membrane] (Homo sapiens)
Recruitment of Sec31p:Sec13p to prebudding complex and formation of COPII vesicle (Homo sapiens)
COPII vesicle with MHC class I [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
Sar1p:GTP:Sec23p:Sec24p:Ag bound MHC class I [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
SEC23:SEC24 [endoplasmic reticulum membrane] (Homo sapiens)
SEC24 [endoplasmic reticulum membrane] (Homo sapiens)
SEC24D [endoplasmic reticulum membrane] (Homo sapiens)
Sar1p:GTP:Sec23p:Sec24p:Ag bound MHC class I [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
SEC23:SEC24 [endoplasmic reticulum membrane] (Homo sapiens)
SEC24 [endoplasmic reticulum membrane] (Homo sapiens)
SEC24D [endoplasmic reticulum membrane] (Homo sapiens)
MHC class II antigen presentation (Homo sapiens)
Formation of COPII vesicle (Homo sapiens)
COPII [endoplasmic reticulum membrane] (Homo sapiens)
SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Homo sapiens)
SEC23:SEC24 [endoplasmic reticulum membrane] (Homo sapiens)
SEC24 [endoplasmic reticulum membrane] (Homo sapiens)
SEC24D [endoplasmic reticulum membrane] (Homo sapiens)
Nonameric complex in COPII vesicle [ER to Golgi transport vesicle membrane] (Homo sapiens)
COPII [endoplasmic reticulum membrane] (Homo sapiens)
SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Homo sapiens)
SEC23:SEC24 [endoplasmic reticulum membrane] (Homo sapiens)
SEC24 [endoplasmic reticulum membrane] (Homo sapiens)
SEC24D [endoplasmic reticulum membrane] (Homo sapiens)
Fusion of COPII vesicle with Golgi complex (Homo sapiens)
COPII [endoplasmic reticulum membrane] (Homo sapiens)
SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Homo sapiens)
SEC23:SEC24 [endoplasmic reticulum membrane] (Homo sapiens)
SEC24 [endoplasmic reticulum membrane] (Homo sapiens)
SEC24D [endoplasmic reticulum membrane] (Homo sapiens)
Nonameric complex in COPII vesicle [ER to Golgi transport vesicle membrane] (Homo sapiens)
COPII [endoplasmic reticulum membrane] (Homo sapiens)
SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Homo sapiens)
SEC23:SEC24 [endoplasmic reticulum membrane] (Homo sapiens)
SEC24 [endoplasmic reticulum membrane] (Homo sapiens)
SEC24D [endoplasmic reticulum membrane] (Homo sapiens)
Metabolism (Homo sapiens)
Metabolism of lipids (Homo sapiens)
Metabolism of steroids (Homo sapiens)
Regulation of cholesterol biosynthesis by SREBP (SREBF) (Homo sapiens)
SREBP1A,1C,2:SCAP binds CopII Coat Complex (Homo sapiens)
SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Homo sapiens)
SEC23:SEC24 [endoplasmic reticulum membrane] (Homo sapiens)
SEC24 [endoplasmic reticulum membrane] (Homo sapiens)
SEC24D [endoplasmic reticulum membrane] (Homo sapiens)
SREBP1A,1C,2:SCAP:Cop II Coat [endoplasmic reticulum membrane] (Homo sapiens)
SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Homo sapiens)
SEC23:SEC24 [endoplasmic reticulum membrane] (Homo sapiens)
SEC24 [endoplasmic reticulum membrane] (Homo sapiens)
SEC24D [endoplasmic reticulum membrane] (Homo sapiens)
SREBP1A,1C,2:SCAP translocates to the Golgi (Homo sapiens)
SREBP1A,1C,2:SCAP:Cop II Coat [endoplasmic reticulum membrane] (Homo sapiens)
SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Homo sapiens)
SEC23:SEC24 [endoplasmic reticulum membrane] (Homo sapiens)
SEC24 [endoplasmic reticulum membrane] (Homo sapiens)
SEC24D [endoplasmic reticulum membrane] (Homo sapiens)
Metabolism of proteins (Homo sapiens)
Post-translational protein modification (Homo sapiens)
Asparagine N-linked glycosylation (Homo sapiens)
Transport to the Golgi and subsequent modification (Homo sapiens)
ER to Golgi Anterograde Transport (Homo sapiens)
COPII-mediated vesicle transport (Homo sapiens)
Inner coat assembly and cargo binding (Homo sapiens)
COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Homo sapiens)
SEC23:SEC24 [endoplasmic reticulum membrane] (Homo sapiens)
SEC24 [endoplasmic reticulum membrane] (Homo sapiens)
SEC24D [endoplasmic reticulum membrane] (Homo sapiens)
Loss of SAR1B GTPase (Homo sapiens)
COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Homo sapiens)
SEC23:SEC24 [endoplasmic reticulum membrane] (Homo sapiens)
SEC24 [endoplasmic reticulum membrane] (Homo sapiens)
SEC24D [endoplasmic reticulum membrane] (Homo sapiens)
SEC16 complex binds SAR1B:GTP:SEC23:SEC24 (Homo sapiens)
COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Homo sapiens)
SEC23:SEC24 [endoplasmic reticulum membrane] (Homo sapiens)
SEC24 [endoplasmic reticulum membrane] (Homo sapiens)
SEC24D [endoplasmic reticulum membrane] (Homo sapiens)
COPII cargo:receptors:SAR1B:GTP:SEC23:SEC24:SEC16A:SEC16B:TFG hexamer [endoplasmic reticulum membrane] (Homo sapiens)
COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Homo sapiens)
SEC23:SEC24 [endoplasmic reticulum membrane] (Homo sapiens)
SEC24 [endoplasmic reticulum membrane] (Homo sapiens)
SEC24D [endoplasmic reticulum membrane] (Homo sapiens)
SEC31:SEC13 and v-SNARE recruitment (Homo sapiens)
COPII cargo:receptors:SAR1B:GTP:SEC23:SEC24:SEC16A:SEC16B:TFG hexamer [endoplasmic reticulum membrane] (Homo sapiens)
COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Homo sapiens)
SEC23:SEC24 [endoplasmic reticulum membrane] (Homo sapiens)
SEC24 [endoplasmic reticulum membrane] (Homo sapiens)
SEC24D [endoplasmic reticulum membrane] (Homo sapiens)
COPII cargo:receptors:SAR1B:GTP:SEC23:SEC24:SEC16A:SEC16B:TFG hexamer:SEC13:SEC31:SEC23IP:v-SNARES [endoplasmic reticulum membrane] (Homo sapiens)
COPII cargo:receptors:SAR1B:GTP:SEC23:SEC24:SEC16A:SEC16B:TFG hexamer [endoplasmic reticulum membrane] (Homo sapiens)
COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Homo sapiens)
SEC23:SEC24 [endoplasmic reticulum membrane] (Homo sapiens)
SEC24 [endoplasmic reticulum membrane] (Homo sapiens)
SEC24D [endoplasmic reticulum membrane] (Homo sapiens)
Vesicle budding (Homo sapiens)
COPII cargo:receptors:SAR1B:GTP:SEC23:SEC24:SEC16A:SEC16B:TFG hexamer:SEC13:SEC31:SEC23IP:v-SNARES [endoplasmic reticulum membrane] (Homo sapiens)
COPII cargo:receptors:SAR1B:GTP:SEC23:SEC24:SEC16A:SEC16B:TFG hexamer [endoplasmic reticulum membrane] (Homo sapiens)
COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Homo sapiens)
SEC23:SEC24 [endoplasmic reticulum membrane] (Homo sapiens)
SEC24 [endoplasmic reticulum membrane] (Homo sapiens)
SEC24D [endoplasmic reticulum membrane] (Homo sapiens)
Cargo concentration in the ER (Homo sapiens)
Inner coat assembly and cargo binding (Homo sapiens)
COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Homo sapiens)
SEC23:SEC24 [endoplasmic reticulum membrane] (Homo sapiens)
SEC24 [endoplasmic reticulum membrane] (Homo sapiens)
SEC24D [endoplasmic reticulum membrane] (Homo sapiens)
Vesicle-mediated transport (Homo sapiens)
Membrane Trafficking (Homo sapiens)
ER to Golgi Anterograde Transport (Homo sapiens)
COPII-mediated vesicle transport (Homo sapiens)
Inner coat assembly and cargo binding (Homo sapiens)
COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Homo sapiens)
SEC23:SEC24 [endoplasmic reticulum membrane] (Homo sapiens)
SEC24 [endoplasmic reticulum membrane] (Homo sapiens)
SEC24D [endoplasmic reticulum membrane] (Homo sapiens)
Loss of SAR1B GTPase (Homo sapiens)
COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Homo sapiens)
SEC23:SEC24 [endoplasmic reticulum membrane] (Homo sapiens)
SEC24 [endoplasmic reticulum membrane] (Homo sapiens)
SEC24D [endoplasmic reticulum membrane] (Homo sapiens)
SEC16 complex binds SAR1B:GTP:SEC23:SEC24 (Homo sapiens)
COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Homo sapiens)
SEC23:SEC24 [endoplasmic reticulum membrane] (Homo sapiens)
SEC24 [endoplasmic reticulum membrane] (Homo sapiens)
SEC24D [endoplasmic reticulum membrane] (Homo sapiens)
COPII cargo:receptors:SAR1B:GTP:SEC23:SEC24:SEC16A:SEC16B:TFG hexamer [endoplasmic reticulum membrane] (Homo sapiens)
COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Homo sapiens)
SEC23:SEC24 [endoplasmic reticulum membrane] (Homo sapiens)
SEC24 [endoplasmic reticulum membrane] (Homo sapiens)
SEC24D [endoplasmic reticulum membrane] (Homo sapiens)
SEC31:SEC13 and v-SNARE recruitment (Homo sapiens)
COPII cargo:receptors:SAR1B:GTP:SEC23:SEC24:SEC16A:SEC16B:TFG hexamer [endoplasmic reticulum membrane] (Homo sapiens)
COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Homo sapiens)
SEC23:SEC24 [endoplasmic reticulum membrane] (Homo sapiens)
SEC24 [endoplasmic reticulum membrane] (Homo sapiens)
SEC24D [endoplasmic reticulum membrane] (Homo sapiens)
COPII cargo:receptors:SAR1B:GTP:SEC23:SEC24:SEC16A:SEC16B:TFG hexamer:SEC13:SEC31:SEC23IP:v-SNARES [endoplasmic reticulum membrane] (Homo sapiens)
COPII cargo:receptors:SAR1B:GTP:SEC23:SEC24:SEC16A:SEC16B:TFG hexamer [endoplasmic reticulum membrane] (Homo sapiens)
COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Homo sapiens)
SEC23:SEC24 [endoplasmic reticulum membrane] (Homo sapiens)
SEC24 [endoplasmic reticulum membrane] (Homo sapiens)
SEC24D [endoplasmic reticulum membrane] (Homo sapiens)
Vesicle budding (Homo sapiens)
COPII cargo:receptors:SAR1B:GTP:SEC23:SEC24:SEC16A:SEC16B:TFG hexamer:SEC13:SEC31:SEC23IP:v-SNARES [endoplasmic reticulum membrane] (Homo sapiens)
COPII cargo:receptors:SAR1B:GTP:SEC23:SEC24:SEC16A:SEC16B:TFG hexamer [endoplasmic reticulum membrane] (Homo sapiens)
COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Homo sapiens)
SEC23:SEC24 [endoplasmic reticulum membrane] (Homo sapiens)
SEC24 [endoplasmic reticulum membrane] (Homo sapiens)
SEC24D [endoplasmic reticulum membrane] (Homo sapiens)
Cargo concentration in the ER (Homo sapiens)
Inner coat assembly and cargo binding (Homo sapiens)
COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Homo sapiens)
SEC23:SEC24 [endoplasmic reticulum membrane] (Homo sapiens)
SEC24 [endoplasmic reticulum membrane] (Homo sapiens)
SEC24D [endoplasmic reticulum membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:O94855 SEC24D
Gene Names
SEC24D, KIAA0755
Chain
chain:1-1032
Reference Genes
BioGPS Gene:9871 SEC24D
COSMIC (genes):SEC24D SEC24D
CTD Gene:9871 SEC24D
dbSNP Gene:9871 SEC24D
ENSEMBL:ENSG00000150961 SEC24D
HGNC:10706 SEC24D
KEGG Gene (Homo sapiens):9871 SEC24D
Monarch:9871 SEC24D
NCBI Gene:9871 SEC24D
OMIM:607186 SEC24D
UCSC:O94855 SEC24D
Reference Transcript
RefSeq:NM_001318066.1 SEC24D
RefSeq:NM_014822.3 SEC24D
RefSeq:XM_005263379.2 SEC24D
Other Identifiers
0005130593
11717319_a_at
11746083_a_at
16979256
202375_at
2783317
2783318
2783325
2783328
2783329
2783336
2783338
2783340
2783341
2783343
2783344
2783345
2783347
2783349
2783352
2783355
2783356
2783364
2783365
2783367
2783368
2783369
2783375
2783380
2783383
2783384
2783385
2783386
32770_at
69085_s_at
8102482
9871
A_23_P159382
GE53464
GO:0000149
GO:0001701
GO:0002376
GO:0002474
GO:0003674
GO:0005515
GO:0005575
GO:0005622
GO:0005737
GO:0005783
GO:0005789
GO:0005829
GO:0006810
GO:0006886
GO:0006888
GO:0008150
GO:0008270
GO:0009790
GO:0012507
GO:0015031
GO:0016020
GO:0016192
GO:0019886
GO:0022607
GO:0030127
GO:0031410
GO:0032991
GO:0043167
GO:0043226
GO:0043231
GO:0046872
GO:0048208
GO:0048856
GO:0061024
GO:0065003
GO:0070971
GO:0090110
HMNXSV003038254
ILMN_1656386
PH_hs_0024795
TC04001496.hg
g7662658_3p_at
Participates
as a member of
SEC24 [endoplasmic reticulum membrane] (Homo sapiens)
Other forms of this molecule
p-SEC24D [cytosol]
SEC24D [ER to Golgi transport vesicle membrane]
SEC24D [cytosol]
Inferred To
Sec24d [endoplasmic reticulum membrane]
(Mus musculus)
Sec24d [endoplasmic reticulum membrane]
(Rattus norvegicus)
sec24d [endoplasmic reticulum membrane]
(Danio rerio)
SFB3 [endoplasmic reticulum membrane]
(Saccharomyces cerevisiae)
sec-24.1 [endoplasmic reticulum membrane]
(Caenorhabditis elegans)
SEC24D [endoplasmic reticulum membrane]
(Bos taurus)
SEC24D [endoplasmic reticulum membrane]
(Canis familiaris)
SEC24D [endoplasmic reticulum membrane]
(Gallus gallus)
SEC24D [endoplasmic reticulum membrane]
(Plasmodium falciparum)
SEC24D [endoplasmic reticulum membrane]
(Schizosaccharomyces pombe)
SEC24D [endoplasmic reticulum membrane]
(Sus scrofa)
sec24l [endoplasmic reticulum membrane]
(Dictyostelium discoideum)
Cross References
RefSeq
NP_001304995.1
,
XP_005263436.1
,
NP_055637.2
OpenTargets
ENSG00000150961
HPA
ENSG00000150961-SEC24D
GeneCards
O94855
Ensembl
ENSP00000280551
,
ENSG00000150961
,
ENST00000280551
PRO
O94855
Pharos - Targets
O94855
GlyGen
O94855
Orphanet
23212
PDB
3EFO
,
5KYX
,
5KYU
,
5KYY
,
5KYW
,
3EG9
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