The Drosha:DGCR8 complex is also known as the MicroProcessor Complex. Drosha:DGCR8 contains DGCR8, an RNA-binding protein, and Drosha, an RNaseIII-class endonuclease that cleaves double-stranded RNA, leaving a 2-nucleotide protrusion at the 3' end.
© 2018 Reactome