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MicroProcessor Complex [nucleoplasm]
Stable Identifier
R-HSA-203817
Type
Complex
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
DGCR8:Drosha
Locations in the PathwayBrowser
Expand all
Gene expression (Transcription) (Homo sapiens)
Gene Silencing by RNA (Homo sapiens)
MicroRNA (miRNA) biogenesis (Homo sapiens)
Microprocessor complex cleaves pri-miRNA to pre-miRNA (Homo sapiens)
MicroProcessor Complex [nucleoplasm] (Homo sapiens)
General
The Drosha:DGCR8 complex is also known as the MicroProcessor Complex. Drosha:DGCR8 contains DGCR8, an RNA-binding protein, and Drosha, an RNaseIII-class endonuclease that cleaves double-stranded RNA, leaving a 2-nucleotide protrusion at the 3' end.
Participants
components
DGCR8 [nucleoplasm]
(Homo sapiens)
DROSHA [nucleoplasm]
(Homo sapiens)
Cross References
ComplexPortal
CPX-3080
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