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Activated FGFR3 G382D mutant [plasma membrane]
Stable Identifier
R-HSA-2033323
Type
Complex
Species
Homo sapiens
Compartment
plasma membrane
Locations in the PathwayBrowser
Expand all
Disease (Homo sapiens)
Diseases of signal transduction by growth factor receptors and second messengers (Homo sapiens)
Signaling by FGFR in disease (Homo sapiens)
Signaling by FGFR3 in disease (Homo sapiens)
Signaling by FGFR3 point mutants in cancer (Homo sapiens)
Activated FGFR3 mutant-associated PI3K phosphorylates PIP2 to PIP3 (Homo sapiens)
Activated FGFR3 mutants:p-FRS2:GRB2:GAB1:PI3K [plasma membrane] (Homo sapiens)
Activated FGFR3 mutants:p-FRS2:GRB2:GAB1:PIK3R1 [plasma membrane] (Homo sapiens)
Activated FGFR3 mutants:p-FRS2 [plasma membrane] (Homo sapiens)
Activated FGFR3 mutants [plasma membrane] (Homo sapiens)
Activated FGFR3 mutants with enhanced kinase activity [plasma membrane] (Homo sapiens)
Activated FGFR3 G382D mutant [plasma membrane] (Homo sapiens)
Activated FGFR3 t(4;14) translocation mutants [plasma membrane] (Homo sapiens)
Activated FGFR3 G382D mutant [plasma membrane] (Homo sapiens)
Activated FGFR3 mutants bind FRS2 (Homo sapiens)
Activated FGFR3 mutants [plasma membrane] (Homo sapiens)
Activated FGFR3 mutants with enhanced kinase activity [plasma membrane] (Homo sapiens)
Activated FGFR3 G382D mutant [plasma membrane] (Homo sapiens)
Activated FGFR3 t(4;14) translocation mutants [plasma membrane] (Homo sapiens)
Activated FGFR3 G382D mutant [plasma membrane] (Homo sapiens)
Activated FGFR3 mutants:FRS2 [plasma membrane] (Homo sapiens)
Activated FGFR3 mutants [plasma membrane] (Homo sapiens)
Activated FGFR3 mutants with enhanced kinase activity [plasma membrane] (Homo sapiens)
Activated FGFR3 G382D mutant [plasma membrane] (Homo sapiens)
Activated FGFR3 t(4;14) translocation mutants [plasma membrane] (Homo sapiens)
Activated FGFR3 G382D mutant [plasma membrane] (Homo sapiens)
Activated FGFR3 mutants bind PLCG1 (Homo sapiens)
Activated FGFR3 mutants [plasma membrane] (Homo sapiens)
Activated FGFR3 mutants with enhanced kinase activity [plasma membrane] (Homo sapiens)
Activated FGFR3 G382D mutant [plasma membrane] (Homo sapiens)
Activated FGFR3 t(4;14) translocation mutants [plasma membrane] (Homo sapiens)
Activated FGFR3 G382D mutant [plasma membrane] (Homo sapiens)
Activated FGFR3 mutants: PLCG1 [plasma membrane] (Homo sapiens)
Activated FGFR3 mutants [plasma membrane] (Homo sapiens)
Activated FGFR3 mutants with enhanced kinase activity [plasma membrane] (Homo sapiens)
Activated FGFR3 G382D mutant [plasma membrane] (Homo sapiens)
Activated FGFR3 t(4;14) translocation mutants [plasma membrane] (Homo sapiens)
Activated FGFR3 G382D mutant [plasma membrane] (Homo sapiens)
Activated FGFR3 mutants phosphorylate FRS2 (Homo sapiens)
Activated FGFR3 mutants:FRS2 [plasma membrane] (Homo sapiens)
Activated FGFR3 mutants [plasma membrane] (Homo sapiens)
Activated FGFR3 mutants with enhanced kinase activity [plasma membrane] (Homo sapiens)
Activated FGFR3 G382D mutant [plasma membrane] (Homo sapiens)
Activated FGFR3 t(4;14) translocation mutants [plasma membrane] (Homo sapiens)
Activated FGFR3 G382D mutant [plasma membrane] (Homo sapiens)
Activated FGFR3 mutants:p-FRS2 [plasma membrane] (Homo sapiens)
Activated FGFR3 mutants [plasma membrane] (Homo sapiens)
Activated FGFR3 mutants with enhanced kinase activity [plasma membrane] (Homo sapiens)
Activated FGFR3 G382D mutant [plasma membrane] (Homo sapiens)
Activated FGFR3 t(4;14) translocation mutants [plasma membrane] (Homo sapiens)
Activated FGFR3 G382D mutant [plasma membrane] (Homo sapiens)
Activated FGFR3 mutants phosphorylate PLCG1 (Homo sapiens)
Activated FGFR3 mutants: PLCG1 [plasma membrane] (Homo sapiens)
Activated FGFR3 mutants [plasma membrane] (Homo sapiens)
Activated FGFR3 mutants with enhanced kinase activity [plasma membrane] (Homo sapiens)
Activated FGFR3 G382D mutant [plasma membrane] (Homo sapiens)
Activated FGFR3 t(4;14) translocation mutants [plasma membrane] (Homo sapiens)
Activated FGFR3 G382D mutant [plasma membrane] (Homo sapiens)
Activated FGFR3 mutants:p-4Y-PLCG1 [plasma membrane] (Homo sapiens)
Activated FGFR3 mutants [plasma membrane] (Homo sapiens)
Activated FGFR3 mutants with enhanced kinase activity [plasma membrane] (Homo sapiens)
Activated FGFR3 G382D mutant [plasma membrane] (Homo sapiens)
Activated FGFR3 t(4;14) translocation mutants [plasma membrane] (Homo sapiens)
Activated FGFR3 G382D mutant [plasma membrane] (Homo sapiens)
Activated FGFR3 mutants:p-FRS2 binds GRB2-SOS1 (Homo sapiens)
Activated FGFR3 mutants:p-FRS2 [plasma membrane] (Homo sapiens)
Activated FGFR3 mutants [plasma membrane] (Homo sapiens)
Activated FGFR3 mutants with enhanced kinase activity [plasma membrane] (Homo sapiens)
Activated FGFR3 G382D mutant [plasma membrane] (Homo sapiens)
Activated FGFR3 t(4;14) translocation mutants [plasma membrane] (Homo sapiens)
Activated FGFR3 G382D mutant [plasma membrane] (Homo sapiens)
FGFR3 mutants:p-FRS2:GRB2:SOS1 [plasma membrane] (Homo sapiens)
Activated FGFR3 mutants:p-FRS2 [plasma membrane] (Homo sapiens)
Activated FGFR3 mutants [plasma membrane] (Homo sapiens)
Activated FGFR3 mutants with enhanced kinase activity [plasma membrane] (Homo sapiens)
Activated FGFR3 G382D mutant [plasma membrane] (Homo sapiens)
Activated FGFR3 t(4;14) translocation mutants [plasma membrane] (Homo sapiens)
Activated FGFR3 G382D mutant [plasma membrane] (Homo sapiens)
Activated FGFR3 mutants:p-FRS2 binds GRB2:GAB1:PIK3R1 (Homo sapiens)
Activated FGFR3 mutants:p-FRS2 [plasma membrane] (Homo sapiens)
Activated FGFR3 mutants [plasma membrane] (Homo sapiens)
Activated FGFR3 mutants with enhanced kinase activity [plasma membrane] (Homo sapiens)
Activated FGFR3 G382D mutant [plasma membrane] (Homo sapiens)
Activated FGFR3 t(4;14) translocation mutants [plasma membrane] (Homo sapiens)
Activated FGFR3 G382D mutant [plasma membrane] (Homo sapiens)
Activated FGFR3 mutants:p-FRS2:GRB2:GAB1:PIK3R1 [plasma membrane] (Homo sapiens)
Activated FGFR3 mutants:p-FRS2 [plasma membrane] (Homo sapiens)
Activated FGFR3 mutants [plasma membrane] (Homo sapiens)
Activated FGFR3 mutants with enhanced kinase activity [plasma membrane] (Homo sapiens)
Activated FGFR3 G382D mutant [plasma membrane] (Homo sapiens)
Activated FGFR3 t(4;14) translocation mutants [plasma membrane] (Homo sapiens)
Activated FGFR3 G382D mutant [plasma membrane] (Homo sapiens)
Activated FGFR3 mutants:p-FRS2:GRB2:GAB1:PIK3R1 binds PIK3CA (Homo sapiens)
Activated FGFR3 mutants:p-FRS2:GRB2:GAB1:PI3K [plasma membrane] (Homo sapiens)
Activated FGFR3 mutants:p-FRS2:GRB2:GAB1:PIK3R1 [plasma membrane] (Homo sapiens)
Activated FGFR3 mutants:p-FRS2 [plasma membrane] (Homo sapiens)
Activated FGFR3 mutants [plasma membrane] (Homo sapiens)
Activated FGFR3 mutants with enhanced kinase activity [plasma membrane] (Homo sapiens)
Activated FGFR3 G382D mutant [plasma membrane] (Homo sapiens)
Activated FGFR3 t(4;14) translocation mutants [plasma membrane] (Homo sapiens)
Activated FGFR3 G382D mutant [plasma membrane] (Homo sapiens)
Activated FGFR3 mutants:p-FRS2:GRB2:GAB1:PIK3R1 [plasma membrane] (Homo sapiens)
Activated FGFR3 mutants:p-FRS2 [plasma membrane] (Homo sapiens)
Activated FGFR3 mutants [plasma membrane] (Homo sapiens)
Activated FGFR3 mutants with enhanced kinase activity [plasma membrane] (Homo sapiens)
Activated FGFR3 G382D mutant [plasma membrane] (Homo sapiens)
Activated FGFR3 t(4;14) translocation mutants [plasma membrane] (Homo sapiens)
Activated FGFR3 G382D mutant [plasma membrane] (Homo sapiens)
Activated FGFR3 mutants:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange (Homo sapiens)
FGFR3 mutants:p-FRS2:GRB2:SOS1 [plasma membrane] (Homo sapiens)
Activated FGFR3 mutants:p-FRS2 [plasma membrane] (Homo sapiens)
Activated FGFR3 mutants [plasma membrane] (Homo sapiens)
Activated FGFR3 mutants with enhanced kinase activity [plasma membrane] (Homo sapiens)
Activated FGFR3 G382D mutant [plasma membrane] (Homo sapiens)
Activated FGFR3 t(4;14) translocation mutants [plasma membrane] (Homo sapiens)
Activated FGFR3 G382D mutant [plasma membrane] (Homo sapiens)
FGFR3 mutant receptor activation (Homo sapiens)
Signaling by activated point mutants of FGFR3 (Homo sapiens)
Autocatalytic phosphorylation of FGFR3 point mutants with enhanced kinase activity (Homo sapiens)
Activated FGFR3 mutants with enhanced kinase activity [plasma membrane] (Homo sapiens)
Activated FGFR3 G382D mutant [plasma membrane] (Homo sapiens)
t(4;14) translocations of FGFR3 (Homo sapiens)
Autocatalytic phosphorylation of FGFR3 t(4;14) translocation mutants (Homo sapiens)
Activated FGFR3 t(4;14) translocation mutants [plasma membrane] (Homo sapiens)
Activated FGFR3 G382D mutant [plasma membrane] (Homo sapiens)
p-4Y-PLCG1 dissociates from activated FGFR3 mutants (Homo sapiens)
Activated FGFR3 mutants [plasma membrane] (Homo sapiens)
Activated FGFR3 mutants with enhanced kinase activity [plasma membrane] (Homo sapiens)
Activated FGFR3 G382D mutant [plasma membrane] (Homo sapiens)
Activated FGFR3 t(4;14) translocation mutants [plasma membrane] (Homo sapiens)
Activated FGFR3 G382D mutant [plasma membrane] (Homo sapiens)
Activated FGFR3 mutants:p-4Y-PLCG1 [plasma membrane] (Homo sapiens)
Activated FGFR3 mutants [plasma membrane] (Homo sapiens)
Activated FGFR3 mutants with enhanced kinase activity [plasma membrane] (Homo sapiens)
Activated FGFR3 G382D mutant [plasma membrane] (Homo sapiens)
Activated FGFR3 t(4;14) translocation mutants [plasma membrane] (Homo sapiens)
Activated FGFR3 G382D mutant [plasma membrane] (Homo sapiens)
Participants
components
x 2
p-6Y-FGFR3 G382D [plasma membrane]
(Homo sapiens)
Participates
as a member of
Activated FGFR3 t(4;14) translocation mutants [plasma membrane] (Homo sapiens)
Activated FGFR3 mutants with enhanced kinase activity [plasma membrane] (Homo sapiens)
Disease
Name
Identifier
Synonyms
multiple myeloma
DOID:9538
cancer
DOID:162
malignant tumor, malignant neoplasm, primary cancer
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