WWTR1 (TAZ) binds TEAD

Stable Identifier
R-HSA-2032781
Type
Reaction [binding]
Species
Homo sapiens
Compartment
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In the nucleus the WWTR1 (TAZ) transcriptional coactivator can bind any one of the four TEAD transcription factors to form a complex. The stoichiometry of this complex is unknown (Chan et al. 2009; Zhang et al. 2009).

Literature References
PubMed ID Title Journal Year
19324876 TEADs mediate nuclear retention of TAZ to promote oncogenic transformation

Chan, SW, Lim, CJ, Loo, LS, Chong, YF, Huang, C, Hong, W

J Biol Chem 2009
19324877 TEAD transcription factors mediate the function of TAZ in cell growth and epithelial-mesenchymal transition

Zhang, H, Liu, CY, Zha, ZY, Zhao, B, Yao, J, Zhao, S, Xiong, Y, Lei, Q, Guan, KL

J Biol Chem 2009
Participants
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Orthologous Events
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