Reactome | TEAD4 [nucleoplasm]

TEAD4 [nucleoplasm]

Stable Identifier

R-HSA-2032780

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

Transcriptional enhancer factor TEF-3

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:Q15561 TEAD4

Gene Names

TEAD4, RTEF1, TCF13L1, TEF3

Chain

chain:1-434

Reference Genes

BioGPS Gene:7004 TEAD4

COSMIC (genes):TEAD4 TEAD4

CTD Gene:7004 TEAD4

dbSNP Gene:7004 TEAD4

ENSEMBL:ENSG00000197905 TEAD4

HGNC:11717 TEAD4

KEGG Gene (Homo sapiens):7004 TEAD4

Monarch:7004 TEAD4

NCBI Gene:7004 TEAD4

OMIM:601714 TEAD4

UCSC:Q15561 TEAD4

Reference Transcript

Other Identifiers

0006180133

11733699_a_at

16746906

204281_at

2951504

3401262

3401263

3401264

3401280

3401282

3401290

3401291

3401292

3401294

3401295

3401296

3401297

3401298

3401299

3401304

3401306

3401307

3401308

3401309

41037_at

7004

7953150

GE59304

GO:0000228

GO:0000790

GO:0000978

GO:0000981

GO:0001228

GO:0001501

GO:0003674

GO:0003677

GO:0003700

GO:0005515

GO:0005575

GO:0005622

GO:0005634

GO:0005654

GO:0005667

GO:0005694

GO:0006351

GO:0006355

GO:0006357

GO:0006367

GO:0007165

GO:0007517

GO:0008150

GO:0009058

GO:0009790

GO:0032991

GO:0034641

GO:0035329

GO:0043226

GO:0045944

GO:0048568

GO:0048856

ILMN_1705301

ILMN_1722824

ILMN_2413041

TC12000034.hg

U63824_at

g4507426_3p_s_at

Participant Of

hasMember

hasComponent

TEAD4:YAP1 [nucleoplasm]

input

YAP1 binds TEAD4

Inferred To

egl-44 [nucleoplasm] (Caenorhabditis elegans)

TEAD4 [nucleoplasm] (Bos taurus)

TEAD4 [nucleoplasm] (Canis familiaris)

TEAD4 [nucleoplasm] (Gallus gallus)

TEAD4 [nucleoplasm] (Sus scrofa)

sd [nucleoplasm] (Drosophila melanogaster)

Tead4 [nucleoplasm] (Mus musculus)

Tead4 [nucleoplasm] (Rattus norvegicus)

TEC1 [nucleoplasm] (Saccharomyces cerevisiae)

Cross References

RefSeq

NP_003204.2, NP_958851.1, NP_958849.1

Target Pathogen

5b354852be737e166372ee70

OpenTargets

ENSG00000197905

HPA

ENSG00000197905-TEAD4

GeneCards

Q15561

Ensembl

ENSG00000197905, ENST00000397122, ENSP00000380311

PRO

Q15561

PDB

6GEI, 6GE3, 6SEN, 6HIK, 6GEE, 6Q2X, 5NO6, 6GEC, 6GE4, 5GZB, 6GE6, 6SEO, 6GEG, 6Q36, 6GE5, 5OAQ, 6GEK

Interactors (41)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P46937 YAP1	7	p-Y-YAP1 [cytosol] (R-HSA-8937843) p-Y407-YAP1 [nucleoplasm] (R-HSA-8956661) p-Y-YAP1 [nucleoplasm] (R-HSA-8937857) p-S127-YAP1 [cytosol] (R-HSA-2028553) p-5S-YAP1 [cytosol] (R-HSA-2028554) YAP1 [nucleoplasm] (R-HSA-1253322) YAP1 [cytosol] (R-HSA-1253345)	0.863	10
UniProt:Q9GZV5 WWTR1	3	WWTR1 [cytosol] (R-HSA-1629773) WWTR1 [nucleoplasm] (R-HSA-1629775) p-S89-WWTR1 [cytosol] (R-HSA-2028665)	0.851	9
UniProt:Q53EZ4 CEP55			0.742	5
UniProt:Q08379 GOLGA2	3	GOLGA2 [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-HSA-2167933) p-S37-GOLGA2 [Golgi membrane] (R-HSA-2172179) GOLGA2 [Golgi membrane] (R-HSA-6808764)	0.718	6
UniProt:P14373 TRIM27	2	TRIM27 [cytosol] (R-HSA-8851002) TRIM27 [nucleoplasm] (R-HSA-2997690)	0.718	6
UniProt:Q13077 TRAF1	3	TRAF1(1-163) [cytosol] (R-HSA-5634199) TRAF1 [cytosol] (R-HSA-5634163) TRAF1(164-416) [cytosol] (R-HSA-5634204)	0.718	6
UniProt:Q5JR59-3 MTUS2			0.718	6
UniProt:Q6A162 KRT40	1	KRT40 [cytosol] (R-HSA-6809605)	0.718	6
UniProt:Q9NP79 VTA1	1	VTA1 [cytosol] (R-HSA-917735)	0.666	4
UniProt:Q14135 VGLL4			0.602	3
IntAct:EBI-16430628 CCSB ORF ID			0.556	3
UniProt:P31321 PRKAR1B	2	PRKAR1B [ciliary base] (R-HSA-5610409) PRKAR1B [cytosol] (R-HSA-57838)	0.556	3
IntAct:EBI-22314709 CCSB ORF ID			0.556	3
UniProt:Q8IX15-3 HOMEZ			0.556	3
UniProt:Q99990 VGLL1			0.556	3
UniProt:Q01850 CDR2			0.556	3
UniProt:Q86Z20 CC125			0.556	3
UniProt:Q8WWB3 DYDC1			0.556	3
UniProt:P21673 SAT1	1	SAT1 [cytosol] (R-HSA-351236)	0.556	3
UniProt:Q8N1B4 VPS52	1	VPS52 [trans-Golgi network membrane] (R-HSA-6811029)	0.556	3
UniProt:A8MV65-2 VGLL3			0.556	3
UniProt:Q96CS2 HAUS1	1	HAUS1 [cytosol] (R-HSA-8855199)	0.556	3
UniProt:Q86VW0 SESD1			0.556	3
UniProt:Q8ND90 PNMA1			0.556	3
UniProt:Q7Z3Y8 KRT27	1	KRT27 [cytosol] (R-HSA-6809587)	0.556	3
UniProt:O60504 SORBS3	1	SORBS3 [cytosol] (R-HSA-445805)	0.556	3
UniProt:Q01196-8 RUNX1			0.556	5
UniProt:P0C7W6 CC172			0.556	3
UniProt:O95751 LDOC1			0.556	3
UniProt:Q9BYV2 TRI54			0.556	3
UniProt:Q59EK9-3 RUNDC3A			0.556	3
UniProt:Q0VD86 INCA1			0.556	3
UniProt:A6NEM1 GG6L9			0.556	3
UniProt:Q9GZV8 PRDM14	1	PRDM14 [nucleoplasm] (R-HSA-1112608)	0.556	3
UniProt:Q9BRK4 LZTS2			0.556	3
IntAct:EBI-16436244 CCSB ORF ID			0.556	3
UniProt:Q08117-2 TLE5			0.556	3
UniProt:A6NK89 RASFA			0.556	3
UniProt:Q15323 KRT31	1	KRT31 [cytosol] (R-HSA-6809616)	0.556	3
IntAct:EBI-9253952 SUPER			0.544	2
UniProt:Q80V24 VGLL4			0.525	3

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