Reactome | TEAD1 [nucleoplasm]

TEAD1 [nucleoplasm]

Stable Identifier

R-HSA-2032774

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

Transcriptional enhancer factor TEF-1

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:P28347 TEAD1

Gene Names

TEAD1, TCF13, TEF1

Chain

chain:1-426

Reference Genes

BioGPS Gene:7003 TEAD1

COSMIC (genes):TEAD1 TEAD1

CTD Gene:7003 TEAD1

dbSNP Gene:7003 TEAD1

ENSEMBL:ENSG00000187079 TEAD1

ENSEMBL:ENSG00000187079.20 TEAD1

HGNC:11714 TEAD1

KEGG Gene (Homo sapiens):7003 TEAD1

Monarch:7003 TEAD1

NCBI Gene:7003 TEAD1

OMIM:189967 TEAD1

UCSC:P28347 TEAD1

Reference Transcript

RefSeq:NM_021961.5 TEAD1

Other Identifiers

11743817_s_at

11752086_a_at

11752087_s_at

1553322_PM_s_at

1553322_s_at

16722189

214600_PM_at

214600_at

224955_PM_at

224955_at

3320943

3320945

3320946

3320964

3320965

3320966

3320999

3321004

3321019

3321020

3321022

3321023

3321033

3321041

3321043

3321046

3321054

3321056

3321057

3321058

3321060

35380_at

45777_at

61538_r_at

7003

7938544

80632_at

A_14_P119530

A_23_P362893

A_23_P429340

GE56622

GE79157

GO:0000785

GO:0000978

GO:0000981

GO:0003677

GO:0003700

GO:0005515

GO:0005634

GO:0005654

GO:0005667

GO:0005694

GO:0006351

GO:0006355

GO:0006357

GO:0023052

GO:0030307

GO:0035329

GO:0043226

GO:0045893

GO:0045944

GO:0048568

GO:0048856

GO:0065003

GO:0140110

GO:0140552

GO:1902895

GO:1990837

HMNXSV003038832

Hs.155005.0.A2_3p_at

Hs.42458.0.A1_3p_at

Hs2.42458.1.A1_3p_s_at

ILMN_1674049

ILMN_1735055

M63896_at

PH_hs_0035613

TC11000203.hg

Participates

as a member of

as an input of

YAP1 binds TEAD1 (Homo sapiens)

as a component of

Inferred To

egl-44 [nucleoplasm] (Caenorhabditis elegans)

Tead1 [nucleoplasm] (Mus musculus)

Tead1 [nucleoplasm] (Rattus norvegicus)

sd [nucleoplasm] (Drosophila melanogaster)

TEC1 [nucleoplasm] (Saccharomyces cerevisiae)

TEAD1 [nucleoplasm] (Bos taurus)

TEAD1 [nucleoplasm] (Canis familiaris)

TEAD1 [nucleoplasm] (Danio rerio)

TEAD1 [nucleoplasm] (Gallus gallus)

TEAD1 [nucleoplasm] (Sus scrofa)

tead1 [nucleoplasm] (Xenopus tropicalis)

Cross References

RefSeq

NP_068780.2

Guide to Pharmacology - Targets

3240

OpenTargets

ENSG00000187079

GeneCards

P28347

HPA

ENSG00000187079-TEAD1

Ensembl

ENST00000334310, ENSP00000334754, ENSG00000187079, ENSP00000435233, ENST00000527636

PRO

P28347

Pharos - Targets

P28347

Orphanet

15597

PDB

7ZJP, 4RE1, 2HZD, 6IM5, 4Z8E, 6HIL, 7CMM, 3KYS, 5NNX

Interactors (6)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P46937 YAP1	7	p-Y407-YAP1 [nucleoplasm] (R-HSA-8956661) p-Y-YAP1 [cytosol] (R-HSA-8937843) p-Y-YAP1 [nucleoplasm] (R-HSA-8937857) p-S127-YAP1 [cytosol] (R-HSA-2028553) p-5S-YAP1 [cytosol] (R-HSA-2028554) YAP1 [cytosol] (R-HSA-1253345) YAP1 [nucleoplasm] (R-HSA-1253322)	0.94	11
UniProt:P03070 LT			0.623	3
UniProt:Q26366 VG			0.524	3
UniProt:P05412 JUN	4	JUN [nucleoplasm] (R-HSA-450250) p-S63,S73-JUN [nucleoplasm] (R-HSA-450237) JUN [cytosol] (R-HSA-168194) p-S63,S73-JUN [cytosol] (R-HSA-8868682)	0.483	2
UniProt:P17535 JUND	1	JUND [nucleoplasm] (R-HSA-9009924)	0.462	2
UniProt:P15407 FOSL1	1	FOSL1 [nucleoplasm] (R-HSA-9620405)	0.462	2

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