Reactome | TEAD1 [nucleoplasm]

TEAD1 [nucleoplasm]

Stable Identifier

R-HSA-2032774

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

Transcriptional enhancer factor TEF-1

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:P28347 TEAD1

Gene Names

TEAD1, TCF13, TEF1

Chain

chain:1-426

Reference Genes

COSMIC (genes):TEAD1 TEAD1

dbSNP Gene:7003 TEAD1

ENSEMBL:ENSG00000187079 TEAD1

Participates

as an input of

YAP1 binds TEAD1 (Homo sapiens)

as a member of

as a component of

Inferred To

egl-44 [nucleoplasm] (Caenorhabditis elegans)

Tead1 [nucleoplasm] (Mus musculus)

Tead1 [nucleoplasm] (Rattus norvegicus)

sd [nucleoplasm] (Drosophila melanogaster)

TEC1 [nucleoplasm] (Saccharomyces cerevisiae)

TEAD1 [nucleoplasm] (Bos taurus)

TEAD1 [nucleoplasm] (Canis familiaris)

TEAD1 [nucleoplasm] (Gallus gallus)

TEAD1 [nucleoplasm] (Sus scrofa)

Interactors (11)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P46937 YAP1	8	YAP1 [nucleoplasm] (R-HSA-1253322) YAP1 [cytosol] (R-HSA-1253345) p-S127-YAP1 [cytosol] (R-HSA-2028553) p-5S-YAP1 [cytosol] (R-HSA-2028554) p-Y-YAP1 [nucleoplasm] (R-HSA-8937857) p-Y-YAP1 [cytosol] (R-HSA-8937843) p-Y407-YAP1 [nucleoplasm] (R-HSA-8956661) p-Y407-YAP1 [cytosol] (R-HSA-9865208)	0.94	11
UniProt:P03070 LT			0.623	3
UniProt:Q06609 RAD51	2	RAD51 [nucleoplasm] (R-HSA-62637) p-T309-RAD51 [nucleoplasm] (R-HSA-5685231)	0.564	2
UniProt:Q15561 TEAD4	1	TEAD4 [nucleoplasm] (R-HSA-2032780)	0.527	3
UniProt:Q9GZV5 WWTR1	3	WWTR1 [nucleoplasm] (R-HSA-1629775) WWTR1 [cytosol] (R-HSA-1629773) p-S89-WWTR1 [cytosol] (R-HSA-2028665)	0.527	3
UniProt:Q15562 TEAD2	1	TEAD2 [nucleoplasm] (R-HSA-2032763)	0.527	3
UniProt:Q26366 VG			0.524	3
UniProt:Q14135 VGLL4			0.483	2
UniProt:P05412 JUN	4	JUN [nucleoplasm] (R-HSA-450250) p-S63,S73-JUN [nucleoplasm] (R-HSA-450237) JUN [cytosol] (R-HSA-168194) p-S63,S73-JUN [cytosol] (R-HSA-8868682)	0.483	2
UniProt:P17535 JUND	1	JUND [nucleoplasm] (R-HSA-9009924)	0.462	2
UniProt:P15407 FOSL1	1	FOSL1 [nucleoplasm] (R-HSA-9620405)	0.462	2

© 2025 Reactome

Cite Us!