Reactome | AMOTL2 [cytosol]

AMOTL2 [cytosol]

Stable Identifier

R-HSA-2028606

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

Angiomotin-like protein 2

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q9Y2J4 AMOTL2

Gene Names

AMOTL2, KIAA0989

Chain

chain:1-779

Reference Genes

BioGPS Gene:51421 AMOTL2

COSMIC (genes):AMOTL2 AMOTL2

CTD Gene:51421 AMOTL2

dbSNP Gene:51421 AMOTL2

ENSEMBL:ENSG00000114019 AMOTL2

HGNC:17812 AMOTL2

KEGG:hsa:51421 AMOTL2

Monarch:51421 AMOTL2

NCBI Gene:51421 AMOTL2

OMIM:614658 AMOTL2

UCSC:Q9Y2J4 AMOTL2

Reference Transcript

Participates

as a member of

AMOT proteins [cytosol] (Homo sapiens)

Inferred To

Amotl2 [cytosol] (Mus musculus)

Amotl2 [cytosol] (Rattus norvegicus)

AMOTL2 [cytosol] (Bos taurus)

AMOTL2 [cytosol] (Canis familiaris)

AMOTL2 [cytosol] (Gallus gallus)

AMOTL2 [cytosol] (Sus scrofa)

amotl2a [cytosol] (Danio rerio)

Cross References

OpenTargets

ENSG00000114019

ENSEMBL

ENST00000514516, ENST00000249883, ENSP00000249883, ENST00000422605, ENSP00000409999, ENST00000513145, ENSG00000114019, ENSP00000425475, ENSP00000424765

HPA

ENSG00000114019-AMOTL2

GeneCards

AMOTL2

PRO

Q9Y2J4

Pharos - Targets

Q9Y2J4

GlyGen

Q9Y2J4

Interactors (15)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:O75771 RAD51D	1	RAD51D [nucleoplasm] (R-HSA-216920)	0.83	8
UniProt:P46937 YAP1	8	YAP1 [cytosol] (R-HSA-1253345) YAP1 [nucleoplasm] (R-HSA-1253322) p-Y-YAP1 [nucleoplasm] (R-HSA-8937857) p-Y-YAP1 [cytosol] (R-HSA-8937843) p-Y407-YAP1 [nucleoplasm] (R-HSA-8956661) p-5S-YAP1 [cytosol] (R-HSA-2028554) p-S127-YAP1 [cytosol] (R-HSA-2028553) p-Y407-YAP1 [cytosol] (R-HSA-9865208)	0.671	5
UniProt:P17980 PSMC3	5	PSMC3 [cytosol] (R-HSA-68774) PSMC3 [nucleoplasm] (R-HSA-174313) PSMC3 [ficolin-1-rich granule lumen] (R-HSA-6800429) PSMC3 [extracellular region] (R-HSA-6806496) PSMC3 [secretory granule lumen] (R-HSA-6800917)	0.666	5
UniProt:P35240 NF2	1	NF2 [plasma membrane] (R-HSA-5669168)	0.643	3
UniProt:Q9HAQ2 KIF9	1	KIF9 [cytosol] (R-HSA-984616)	0.556	3
UniProt:P07947 YES1	2	MyrG-p-Y426-YES1 [plasma membrane] (R-HSA-1810411) YES1 [cytosol] (R-HSA-373640)	0.556	3
UniProt:Q9UER7 DAXX	13	DAXX [nucleoplasm] (R-HSA-3222068) DAXX A36Qfs108 [nucleoplasm] (R-HSA-9673105) DAXX K56 [nucleoplasm] (R-HSA-9673089) DAXX A103Sfs40 [nucleoplasm] (R-HSA-9673121) DAXX C106 [nucleoplasm] (R-HSA-9673079) DAXX E72Nfs72 [nucleoplasm] (R-HSA-9673110) DAXX E104 [nucleoplasm] (R-HSA-9673078) DAXX H26Tfs118 [nucleoplasm] (R-HSA-9673114) DAXX S138 [nucleoplasm] (R-HSA-9673081) DAXX C74* [nucleoplasm] (R-HSA-9673096) DAXX R48Vfs93 [nucleoplasm] (R-HSA-9673103) DAXX L98Vfs13 [nucleoplasm] (R-HSA-9673102) monoSUMO1-K630,K631-DAXX [nucleoplasm] (R-HSA-4086086)	0.556	3
UniProt:P33297	4	PSMC3 [cytosol] (R-SCE-68774) PSMC3 [ficolin-1-rich granule lumen] (R-SCE-6800429) PSMC3 [extracellular region] (R-SCE-6806496) PSMC3 [secretory granule lumen] (R-SCE-6800917)	0.556	3
UniProt:P54646 PRKAA2	4	PRKAA2 [cytosol] (R-HSA-200405) p-T172-PRKAA2 [cytosol] (R-HSA-200417) p-T172-PRKAA2 [nucleoplasm] (R-HSA-164171) PRKAA2 [nucleoplasm] (R-HSA-163682)	0.556	3
UniProt:Q99633 PRPF18	1	PRPF18 [nucleoplasm] (R-HSA-5688093)	0.556	3
UniProt:Q969G3 SMARCE1	1	SMARCE1 [nucleoplasm] (R-HSA-389258)	0.556	3
UniProt:P55081 MFAP1	1	MFAP1 [nucleoplasm] (R-HSA-2396419)	0.556	3
UniProt:Q13895 BYSL	2	BYSL [nucleoplasm] (R-HSA-6791526) BYSL [cytosol] (R-HSA-6791518)	0.556	3
UniProt:Q969R5 L3MBTL2	2	L3MBTL2 [nucleoplasm] (R-HSA-6804477) polySUMO2-K675,K700-L3MBTL2 [nucleoplasm] (R-HSA-6804480)	0.556	3
UniProt:Q8N3R9 MPP5	2	MPP5 [plasma membrane] (R-HSA-419969) MPP5 [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-HSA-9689606)	0.527	4

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