Reactome | AMOTL2 [cytosol]

AMOTL2 [cytosol]

Stable Identifier

R-HSA-2028606

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

Angiomotin-like protein 2

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:Q9Y2J4 AMOTL2

Gene Names

AMOTL2, KIAA0989

Chain

chain:1-779

Reference Genes

BioGPS Gene:51421 AMOTL2

COSMIC (genes):AMOTL2 AMOTL2

CTD Gene:51421 AMOTL2

dbSNP Gene:51421 AMOTL2

ENSEMBL:ENSG00000114019.15 AMOTL2

HGNC:17812 AMOTL2

KEGG Gene (Homo sapiens):51421 AMOTL2

Monarch:51421 AMOTL2

NCBI Gene:51421 AMOTL2

OMIM:614658 AMOTL2

UCSC:Q9Y2J4 AMOTL2

Reference Transcript

Other Identifiers

0006370010

11733006_at

11733007_at

11733008_a_at

16959441

203002_PM_at

203002_at

2696323

2696324

2696325

2696326

2696327

2696328

2696329

2696336

2696337

2696339

2696340

2696341

2696342

2696343

2696344

2696346

2696347

2696354

2696355

2696356

2696357

2696360

38842_at

51421

51846_at

8090852

A_23_P166686

GE53641

GO:0001525

GO:0003365

GO:0005515

GO:0005622

GO:0005737

GO:0005768

GO:0005829

GO:0005886

GO:0005923

GO:0007010

GO:0007163

GO:0016055

GO:0023052

GO:0030036

GO:0030334

GO:0031410

GO:0043226

GO:0048856

GO:0048870

GO:0055037

HMNXSV003002313

ILMN_1778788

PH_hs_0019841

TC03001804.hg

g7705577_3p_at

g7705577_3p_x_at

Participates

as a member of

AMOT proteins [cytosol] (Homo sapiens)

Inferred To

amotl2 [cytosol] (Xenopus tropicalis)

Amotl2 [cytosol] (Mus musculus)

Amotl2 [cytosol] (Rattus norvegicus)

AMOTL2 [cytosol] (Bos taurus)

AMOTL2 [cytosol] (Canis familiaris)

AMOTL2 [cytosol] (Gallus gallus)

AMOTL2 [cytosol] (Sus scrofa)

amotl2a [cytosol] (Danio rerio)

Cross References

RefSeq

NP_001265612.1, XP_006713717.1, XP_016862070.1, XP_016862069.1, XP_016862071.1, NP_057285.3, NP_001265614.1, XP_011511183.1

OpenTargets

ENSG00000114019

GeneCards

Q9Y2J4

HPA

ENSG00000114019-AMOTL2

Ensembl

ENSG00000114019, ENST00000422605, ENST00000249883, ENSP00000249883, ENST00000513145, ENSP00000424765, ENSP00000409999, ENST00000514516, ENSP00000425475

PRO

Q9Y2J4

Pharos - Targets

Q9Y2J4

Interactors (11)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:O75771 RAD51D	1	RAD51D [nucleoplasm] (R-HSA-216920)	0.83	8
UniProt:P46937 YAP1	7	p-5S-YAP1 [cytosol] (R-HSA-2028554) p-S127-YAP1 [cytosol] (R-HSA-2028553) p-Y407-YAP1 [nucleoplasm] (R-HSA-8956661) p-Y-YAP1 [cytosol] (R-HSA-8937843) p-Y-YAP1 [nucleoplasm] (R-HSA-8937857) YAP1 [nucleoplasm] (R-HSA-1253322) YAP1 [cytosol] (R-HSA-1253345)	0.671	5
UniProt:P07947 YES1	2	MyrG-p-Y426-YES1 [plasma membrane] (R-HSA-1810411) YES1 [cytosol] (R-HSA-373640)	0.556	3
UniProt:Q99633 PRPF18	1	PRPF18 [nucleoplasm] (R-HSA-5688093)	0.556	3
UniProt:Q969R5 L3MBTL2	2	L3MBTL2 [nucleoplasm] (R-HSA-6804477) polySUMO2-K675,K700-L3MBTL2 [nucleoplasm] (R-HSA-6804480)	0.556	3
UniProt:P54646 PRKAA2	4	PRKAA2 [cytosol] (R-HSA-200405) p-T172-PRKAA2 [cytosol] (R-HSA-200417) p-T172-PRKAA2 [nucleoplasm] (R-HSA-164171) PRKAA2 [nucleoplasm] (R-HSA-163682)	0.556	3
UniProt:P55081 MFAP1	1	MFAP1 [nucleoplasm] (R-HSA-2396419)	0.556	3
UniProt:Q9UER7 DAXX	13	monoSUMO1-K630,K631-DAXX [nucleoplasm] (R-HSA-4086086) DAXX L98Vfs13 [nucleoplasm] (R-HSA-9673102) DAXX R48Vfs93 [nucleoplasm] (R-HSA-9673103) DAXX C74* [nucleoplasm] (R-HSA-9673096) DAXX S138* [nucleoplasm] (R-HSA-9673081) DAXX H26Tfs118 [nucleoplasm] (R-HSA-9673114) DAXX E104 [nucleoplasm] (R-HSA-9673078) DAXX E72Nfs72 [nucleoplasm] (R-HSA-9673110) DAXX C106 [nucleoplasm] (R-HSA-9673079) DAXX A103Sfs40 [nucleoplasm] (R-HSA-9673121) DAXX K56 [nucleoplasm] (R-HSA-9673089) DAXX A36Qfs*108 [nucleoplasm] (R-HSA-9673105) DAXX [nucleoplasm] (R-HSA-3222068)	0.556	3
UniProt:Q13895 BYSL	2	BYSL [nucleoplasm] (R-HSA-6791526) BYSL [cytosol] (R-HSA-6791518)	0.556	3
UniProt:Q9HAQ2 KIF9	1	KIF9 [cytosol] (R-HSA-984616)	0.556	3
UniProt:P35240 NF2	1	NF2 [plasma membrane] (R-HSA-5669168)	0.527	2

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