Phosphorylation of YAP by LATS1

Stable Identifier
R-HSA-2028598
Type
Reaction [transition]
Species
Homo sapiens
Compartment
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Cytosolic phospho-LATS1, complexed with MOB1, catalyzes the phosphorylation of YAP on five serine residues (Hao et al. 2008).

Literature References
PubMed ID Title Journal Year
18158288 Tumor suppressor LATS1 is a negative regulator of oncogene YAP

Hao, Y, Chun, A, Cheung, K, Rashidi, B, Yang, X

J Biol Chem 2008
Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
protein serine/threonine kinase activity of p-LATS1:p-MOB1 [cytosol]
Physical Entity
Activity
Orthologous Events
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Reviewed
Created