CD84 homodimerises

Stable Identifier
Reaction [binding]
Homo sapiens
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CD84 is a homophilic receptor expressed on T cells, B cells, dendritic cells, monocytes, macrophages, eosinophils, mast cells, granulocytes, and platelets. CD84 expression increases following activation of T cells, B cells, and dendritic cells. CD84 homophilic engagement is known to induce platelet stimulation.

Literature References
PubMed ID Title Journal Year
17563375 Structure of CD84 provides insight into SLAM family function

Yan, Q, Malashkevich, VN, Fedorov, A, Fedorov, E, Cao, E, Lary, JW, Cole, JL, Nathenson, SG, Almo, SC

Proc Natl Acad Sci U S A 2007
11564780 CD84 functions as a homophilic adhesion molecule and enhances IFN-gamma secretion: adhesion is mediated by Ig-like domain 1

Martin, M, Romero, X, de la Fuente, MA, Tovar, V, Zapater, N, Esplugues, E, Pizcueta, P, Bosch, J, Engel, P

J Immunol 2001
Participant Of
Orthologous Events
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