CD177 is a 58- to 64-kDa glycosylphosphatidylinositol-anchored glycoprotein expressed exclusively by neutrophils, neutrophilic metamyelocytes, and myelocytes, but not by any other blood cells. It has been shown that neutrophil-specific CD177 is a heterophilic binding partner of PECAM-1, constituting a novel pathway that promotes neutrophil transmigration.
Kalinowska, A, Losy, J
Sachs, UJ, Andrei-Selmer, CL, Maniar, A, Weiss, T, Paddock, C, Orlova, VV, Choi, EY, Newman, PJ, Preissner, KT, Chavakis, T, Santoso, S
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