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Oligomerization of Bcl10
Stable Identifier
R-HSA-202489
Type
Reaction [binding]
Species
Homo sapiens
Compartment
cytosol
,
plasma membrane
ReviewStatus
5/5
Locations in the PathwayBrowser
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Immune System (Homo sapiens)
Adaptive Immune System (Homo sapiens)
TCR signaling (Homo sapiens)
Downstream TCR signaling (Homo sapiens)
Oligomerization of Bcl10 (Homo sapiens)
General
SBML
|
BioPAX
Level 2
Level 3
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PDF
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|
PNG
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PPTX
|
SBGN
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The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
Association with RIP2 and its phosphorylation allows subsequent trimerization of Bcl10.
Literature References
PubMed ID
Title
Journal
Year
15122200
CARMA1, BCL-10 and MALT1 in lymphocyte development and activation
Thome, M
Nat Rev Immunol
2004
Participants
Input
x 2
p-BCL10 [cytosol]
(Homo sapiens)
Phosphorylated Bcl10 bound to CARMA1 and RIP2 [plasma membrane]
(Homo sapiens)
Output
Bcl10 trimer bound to CARMA1 trimer [plasma membrane]
(Homo sapiens)
Participates
as an event of
Downstream TCR signaling (Homo sapiens)
Orthologous Events
Oligomerization of Bcl10 (Bos taurus)
Oligomerization of Bcl10 (Canis familiaris)
Oligomerization of Bcl10 (Gallus gallus)
Oligomerization of Bcl10 (Mus musculus)
Oligomerization of Bcl10 (Rattus norvegicus)
Oligomerization of Bcl10 (Sus scrofa)
Authored
Garapati, P V (2008-01-24)
Rudd, C.E. (2008-01-24)
de Bono, B (2008-01-24)
Reviewed
Trowsdale, J (2008-02-26)
Created
Garapati, P V (2007-10-30)
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