Oligomerization of CARMA1

Stable Identifier
R-HSA-202443
Type
Reaction [binding]
Species
Homo sapiens
Compartment
plasma membrane, cytosol
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Oligomerization of CARMA1
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After the phosphorylation and activation CARMA1 undergoes oligomerization, likely through its CC domain. CARMA1 is thought to oligomerize first as a trimer which triggers downstream oligomerization cascade that is ultimately necessary for the subsequent activation of the IKK complex.

Literature References
PubMed ID Title Journal Year
15541657 The roles of CARMA1, Bcl10, and MALT1 in antigen receptor signaling

Lin, X, Wang, D

Semin Immunol 2004
Participants
Input
Output
Participant Of
hasEvent
Orthologous Events
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Oligomerization of CARMA1 (Canis familiaris)
Oligomerization of CARMA1 (Danio rerio)
Oligomerization of CARMA1 (Gallus gallus)
Oligomerization of CARMA1 (Mus musculus)
Oligomerization of CARMA1 (Sus scrofa)
Oligomerization of CARMA1 (Xenopus tropicalis)
Authored
Rudd, C.E.  (2008-01-24)
de Bono, B  (2008-01-24)
Garapati, P V  (2008-01-24)
Reviewed
Trowsdale, J  (2008-02-26)
Created
Garapati, P V  (2007-10-29)