Reactome | PLCD1 [plasma membrane]

PLCD1 [plasma membrane]

Stable Identifier

R-HSA-2023880

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

plasma membrane

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:P51178 PLCD1

Gene Names

PLCD1

Chain

chain:1-756

Reference Genes

BioGPS Gene:5333 PLCD1

COSMIC (genes):PLCD1 PLCD1

CTD Gene:5333 PLCD1

dbSNP Gene:5333 PLCD1

ENSEMBL:ENSG00000187091.14 PLCD1

HGNC:9060 PLCD1

KEGG Gene (Homo sapiens):5333 PLCD1

Monarch:5333 PLCD1

NCBI Gene:5333 PLCD1

OMIM:602142 PLCD1

UCSC:P51178 PLCD1

Reference Transcript

Other Identifiers

0004060647

11718816_a_at

16952218

205125_PM_at

205125_at

2669489

2669490

2669492

2669494

2669495

2669497

2669498

2669500

2669501

2669502

2669504

2669506

2669507

2669508

2669509

2669510

2669511

2669512

2669516

2669517

2669520

2669521

2669522

2669523

2669524

2669526

2669527

2669528

37596_at

5333

8086185

A_23_P80739

GE58900

GO:0004435

GO:0005509

GO:0005515

GO:0005546

GO:0005576

GO:0005615

GO:0005622

GO:0005737

GO:0005886

GO:0006629

GO:0006644

GO:0007165

GO:0008081

GO:0008289

GO:0016042

GO:0016787

GO:0023052

GO:0032794

GO:0035556

GO:0043226

GO:0046488

GO:0046872

GO:0048015

GO:0070062

HMNXSV003034892

ILMN_1769394

PH_hs_0027710

TC03001292.hg

TC03002861.hg

U09117_at

g5453909_3p_at

Participates

as a component of

PLCD1:Ca2+ [plasma membrane] (Homo sapiens)

Inferred To

plc-4 [plasma membrane] (Caenorhabditis elegans)

PLCD1 [plasma membrane] (Bos taurus)

PLCD1 [plasma membrane] (Canis familiaris)

PLCD1 [plasma membrane] (Danio rerio)

PLCD1 [plasma membrane] (Dictyostelium discoideum)

PLCD1 [plasma membrane] (Gallus gallus)

PLCD1 [plasma membrane] (Mus musculus)

PLCD1 [plasma membrane] (Plasmodium falciparum)

PLCD1 [plasma membrane] (Rattus norvegicus)

PLCD1 [plasma membrane] (Saccharomyces cerevisiae)

PLCD1 [plasma membrane] (Schizosaccharomyces pombe)

PLCD1 [plasma membrane] (Sus scrofa)

PLCD1 [plasma membrane] (Xenopus tropicalis)

Cross References

RefSeq

NP_006216.2, NP_001124436.1

Guide to Pharmacology - Targets

1409

OpenTargets

ENSG00000187091

ZINC - Substances

PLCD1_HUMAN

ZINC target

P51178

PRO

P51178

IntEnz

3.1.4.11

GeneCards

P51178

HPA

ENSG00000187091-PLCD1

Ensembl

ENSP00000335600, ENSP00000430344, ENST00000463876, ENSG00000187091, ENST00000334661

Pharos - Targets

P51178

ZINC - Predictions - Purchasable

PLCD1_HUMAN

Orphanet

20292

HMDB Protein

HMDBP00247

Interactors (2)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q14974 KPNB1	5	KPNB1 [specific granule lumen] (R-HSA-6799646) KPNB1 [extracellular region] (R-HSA-6806306) KPNB1 [cytosol] (R-HSA-180733) KPNB1 [nucleoplasm] (R-HSA-180714) KPNB1 [ficolin-1-rich granule lumen] (R-HSA-6800978)	0.602	4
UniProt:O14964 HGS	2	HGS [cytosol] (R-HSA-182954) HGS [phagocytic vesicle lumen] (R-HSA-9635660)	0.556	3