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INPP5B(321-993) [plasma membrane]
Stable Identifier
R-HSA-2023845
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
INPP5B
Locations in the PathwayBrowser
Expand all
Metabolism (Homo sapiens)
Inositol phosphate metabolism (Homo sapiens)
Synthesis of IP2, IP, and Ins in the cytosol (Homo sapiens)
I(1,4,5)P3 is dephosphorylated to I(1,4)P2 by INPP5A/B at the plasma membrane (Homo sapiens)
INPP5A/B [plasma membrane] (Homo sapiens)
INPP5B(321-993) [plasma membrane] (Homo sapiens)
Synthesis of IP3 and IP4 in the cytosol (Homo sapiens)
I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5B at the plasma membrane (Homo sapiens)
Inositol polyphosphate 5-phosphatase [plasma membrane] (Homo sapiens)
INPP5B(321-993) [plasma membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:P32019 INPP5B
Gene Names
INPP5B, OCRL2
Chain
chain:1-990, propeptide:991-993
Reference Genes
BioGPS Gene:3633 INPP5B
COSMIC (genes):INPP5B INPP5B
CTD Gene:3633 INPP5B
dbSNP Gene:3633 INPP5B
ENSEMBL:ENSG00000204084 INPP5B
HGNC:6077 INPP5B
KEGG:hsa:3633 INPP5B
Monarch:3633 INPP5B
NCBI Gene:3633 INPP5B
OMIM:147264 INPP5B
UCSC:P32019 INPP5B
Reference Transcript
RefSeq:NM_001297434.1 INPP5B
RefSeq:NM_005540.2 INPP5B
Other Identifiers
11728053_a_at
11751476_a_at
11751977_x_at
1563565_PM_at
1563565_at
16685505
213643_PM_s_at
213643_s_at
213804_PM_at
213804_at
2407414
2407415
2407416
2407417
2407418
2407419
2407420
2407422
2407423
2407424
2407425
33290_at
3633
4043942
4043944
4043945
4043946
4043947
4043948
4043949
4043950
4043951
4043952
4043953
4043954
4043955
4043956
4043957
4043958
4043960
4043961
4043964
4043965
4043966
4043968
4043969
4043970
4043971
4043972
4043973
4043974
4043977
4043978
4043979
4043980
4043981
4043982
4043983
4043984
4043985
4043986
4043987
4043988
4043989
4043990
4043991
4043992
7915101
A_23_P85640
A_24_P332806
GE61332
GE808468
GO:0001701
GO:0003824
GO:0004439
GO:0005515
GO:0005737
GO:0005768
GO:0005793
GO:0005794
GO:0005829
GO:0005886
GO:0006629
GO:0007018
GO:0007165
GO:0007283
GO:0016020
GO:0016787
GO:0016791
GO:0019637
GO:0022414
GO:0030317
GO:0030670
GO:0031410
GO:0031901
GO:0043226
GO:0043647
GO:0046856
GO:0046872
GO:0048856
GO:0048870
GO:0052658
GO:0052659
GO:0052745
GO:0070613
HMNXSV003010516
HMNXSV003018513
HMNXSV003031436
HMNXSV003058298
Hs.182577.0.S1_3p_at
Hs.182577.0.S1_3p_x_at
Hs.182577.1.S1_3p_a_at
Hs2.407126.1.S1_3p_x_at
ILMN_1810116
M74161_at
PH_hs_0032042
TC01002528.hg
Participates
as a member of
INPP5A/B [plasma membrane] (Homo sapiens)
Inositol polyphosphate 5-phosphatase [plasma membrane] (Homo sapiens)
Inferred To
INPP5B(321-993) [plasma membrane]
(Gallus gallus)
INPP5B(321-993) [plasma membrane]
(Mus musculus)
INPP5B(321-993) [plasma membrane]
(Plasmodium falciparum)
INPP5B(321-993) [plasma membrane]
(Schizosaccharomyces pombe)
INPP5B(321-993) [plasma membrane]
(Sus scrofa)
Inpp5b [plasma membrane]
(Rattus norvegicus)
Dd5P4 [plasma membrane]
(Dictyostelium discoideum)
inpp5b [plasma membrane]
(Xenopus tropicalis)
ocrl-1 [plasma membrane]
(Caenorhabditis elegans)
Ocrl [plasma membrane]
(Drosophila melanogaster)
INPP5B [plasma membrane]
(Bos taurus)
INPP5B [plasma membrane]
(Canis familiaris)
Cross References
RefSeq
NP_001284363.1
,
NP_005531.2
Guide to Pharmacology - Targets
1454
ENSEMBL
ENSP00000362115
,
ENST00000373027
,
ENST00000373026
,
ENSP00000362117
,
ENST00000373024
,
ENSP00000362118
OpenTargets
ENSG00000204084
HPA
ENSG00000204084-INPP5B
PRO
P32019
Pharos - Targets
P32019
GlyGen
P32019
HMDB Protein
HMDBP01860
PDB
5A7J
,
5A7I
,
4CML
,
3N9V
,
3MTC
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