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FGFR1 mutant dimers with enhanced kinase activity [plasma membrane]
Stable Identifier
R-HSA-2023433
Type
Set [CandidateSet]
Species
Homo sapiens
Compartment
plasma membrane
Locations in the PathwayBrowser
Expand all
Disease (Homo sapiens)
Diseases of signal transduction by growth factor receptors and second messengers (Homo sapiens)
Signaling by FGFR in disease (Homo sapiens)
Signaling by FGFR1 in disease (Homo sapiens)
FGFR1 mutant receptor activation (Homo sapiens)
Signaling by activated point mutants of FGFR1 (Homo sapiens)
Autocatalytic phosphorylation of FGFR1 mutants with enhanced kinase activity (Homo sapiens)
FGFR1 mutant dimers with enhanced kinase activity [plasma membrane] (Homo sapiens)
Dimerization of FGFR1 point mutants with enhanced kinase activity (Homo sapiens)
FGFR1 mutant dimers with enhanced kinase activity [plasma membrane] (Homo sapiens)
Participants
members
FGFR1 K656E mutant dimer [plasma membrane]
(Homo sapiens)
FGFR1 N546K mutant dimer [plasma membrane]
(Homo sapiens)
candidates
FGFR1 R576W mutant dimer [plasma membrane]
(Homo sapiens)
Participates
as an output of
Dimerization of FGFR1 point mutants with enhanced kinase activity (Homo sapiens)
as an input of
Autocatalytic phosphorylation of FGFR1 mutants with enhanced kinase activity (Homo sapiens)
Disease
Name
Identifier
Synonyms
glioblastoma
DOID:3068
spongioblastoma multiforme, Spongioblastoma multiforme, primary glioblastoma multiforme, Glioblastoma multiforme, Glioblastoma (morphologic abnormality), GBM (Glioblastoma), Glioblastoma NOS (morphologic abnormality)
cancer
DOID:162
malignant tumor, malignant neoplasm, primary cancer
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