NDST1-4 N-deacetylates GlcNAc residues in heparan

Stable Identifier
R-HSA-2022887
Type
Reaction [transition]
Species
Homo sapiens
Compartment
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The bifunctional enzymes heparan sulfate N-deacetylase/N-sulfotransferase 1-4 (NDST1-4) catalyse both the N-deacetylation and the N-sulfation of N-acetylglucosamine (GlcNAc) of heparan (Dixon et al. 1995, Duncan et al. 2006, Aikawa & Esko 1999, Aikawa et al. 2001). The N-deacetylation of a GlcNAc residue to a glucosamine residue is shown here.

Participants
Participates
Catalyst Activity

N-acetylglucosamine deacetylase activity of NDSTs [Golgi membrane]

Orthologous Events
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