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3x4Hyp-3Hyp-COL4A3(29-1670) [endoplasmic reticulum lumen]
Stable Identifier
R-HSA-2022452
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
endoplasmic reticulum lumen
Synonyms
3x4Hyp-3Hyp-COL4A3, 3,4-hydroxyprolyl collagen alpha-3(IV) propeptide, Goodpasture antigen
Locations in the PathwayBrowser
Expand all
Extracellular matrix organization (Homo sapiens)
Collagen formation (Homo sapiens)
Collagen biosynthesis and modifying enzymes (Homo sapiens)
Collagen chain trimerization (Homo sapiens)
Association of procollagen type IV (Homo sapiens)
Alpha-3(IV) chains [endoplasmic reticulum lumen] (Homo sapiens)
3x4Hyp-3Hyp-COL4A3(29-1670) [endoplasmic reticulum lumen] (Homo sapiens)
C-linked procollagen type IV trimers [endoplasmic reticulum lumen] (Homo sapiens)
C-linked procollagen alpha-3(IV), alpha-4(IV) alpha-5(IV) trimer [endoplasmic reticulum lumen] (Homo sapiens)
Alpha-3(IV) chains [endoplasmic reticulum lumen] (Homo sapiens)
3x4Hyp-3Hyp-COL4A3(29-1670) [endoplasmic reticulum lumen] (Homo sapiens)
Collagen prolyl 3-hydroxylase converts 4-Hyp collagen to 3,4-Hyp collagen (Homo sapiens)
Prolyl 3-hydroxylases:Fe2+:3,4-Hyp collagen propeptides [endoplasmic reticulum lumen] (Homo sapiens)
3,4-Hyp collagen propeptides [endoplasmic reticulum lumen] (Homo sapiens)
3x4Hyp-3Hyp-COL4A3(29-1670) [endoplasmic reticulum lumen] (Homo sapiens)
Procollagen lysyl hydroxylases convert collagen lysines to 5-hydroxylysines (Homo sapiens)
Lysyl hydroxylases:Lysyl hydroxylase procollagen substrates [endoplasmic reticulum membrane] (Homo sapiens)
Lysyl hydroxylase procollagen substrates [endoplasmic reticulum lumen] (Homo sapiens)
3,4-Hyp collagen propeptides [endoplasmic reticulum lumen] (Homo sapiens)
3x4Hyp-3Hyp-COL4A3(29-1670) [endoplasmic reticulum lumen] (Homo sapiens)
Procollagen triple helix formation (Homo sapiens)
Collagen and procollagen triple helices:Serpin H1 [endoplasmic reticulum lumen] (Homo sapiens)
Collagen and procollagen triple helices [endoplasmic reticulum lumen] (Homo sapiens)
Non-fibrillar collagens [endoplasmic reticulum lumen] (Homo sapiens)
Tropocollagen type IV [endoplasmic reticulum lumen] (Homo sapiens)
Tropocollagen alpha-3(IV), alpha-4(IV), alpha-5(IV) [endoplasmic reticulum lumen] (Homo sapiens)
Alpha-3(IV) chains [endoplasmic reticulum lumen] (Homo sapiens)
3x4Hyp-3Hyp-COL4A3(29-1670) [endoplasmic reticulum lumen] (Homo sapiens)
Procollagen C-linked trimers [endoplasmic reticulum lumen] (Homo sapiens)
C-linked procollagen type IV trimers [endoplasmic reticulum lumen] (Homo sapiens)
C-linked procollagen alpha-3(IV), alpha-4(IV) alpha-5(IV) trimer [endoplasmic reticulum lumen] (Homo sapiens)
Alpha-3(IV) chains [endoplasmic reticulum lumen] (Homo sapiens)
3x4Hyp-3Hyp-COL4A3(29-1670) [endoplasmic reticulum lumen] (Homo sapiens)
Prolyl 3-hydroxylases:Fe2+:3,4-Hyp collagen propeptides dissociates (Homo sapiens)
3,4-Hyp collagen propeptides [endoplasmic reticulum lumen] (Homo sapiens)
3x4Hyp-3Hyp-COL4A3(29-1670) [endoplasmic reticulum lumen] (Homo sapiens)
Prolyl 3-hydroxylases:Fe2+:3,4-Hyp collagen propeptides [endoplasmic reticulum lumen] (Homo sapiens)
3,4-Hyp collagen propeptides [endoplasmic reticulum lumen] (Homo sapiens)
3x4Hyp-3Hyp-COL4A3(29-1670) [endoplasmic reticulum lumen] (Homo sapiens)
Secretion of collagens (Homo sapiens)
Collagens and tropocollagens:Serpin H1 [endoplasmic reticulum lumen] (Homo sapiens)
Collagens and tropocollagens [endoplasmic reticulum lumen] (Homo sapiens)
Non-fibrillar collagens [endoplasmic reticulum lumen] (Homo sapiens)
Tropocollagen type IV [endoplasmic reticulum lumen] (Homo sapiens)
Tropocollagen alpha-3(IV), alpha-4(IV), alpha-5(IV) [endoplasmic reticulum lumen] (Homo sapiens)
Alpha-3(IV) chains [endoplasmic reticulum lumen] (Homo sapiens)
3x4Hyp-3Hyp-COL4A3(29-1670) [endoplasmic reticulum lumen] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q01955 COL4A3
Gene Names
COL4A3
Chain
signal peptide:1-28, chain:29-1670, chain:1426-1670
Reference Genes
BioGPS Gene:1285 COL4A3
COSMIC (genes):COL4A3 COL4A3
CTD Gene:1285 COL4A3
dbSNP Gene:1285 COL4A3
ENSEMBL:ENSG00000169031 COL4A3
ENSEMBL_homo_sapiens_GENE:ENSG00000169031.21 COL4A3
HGNC:2204 COL4A3
KEGG Gene (Homo sapiens):1285 COL4A3
Monarch:1285 COL4A3
NCBI Gene:1285 COL4A3
OMIM:120070 COL4A3
UCSC:Q01955 COL4A3
Reference Transcript
RefSeq:NM_000091.4 COL4A3
Other Identifiers
11735153_a_at
11735154_a_at
1285
16891662
214641_PM_at
214641_at
216893_PM_s_at
216893_s_at
216898_PM_s_at
216898_s_at
222073_PM_at
222073_at
2530426
2530427
2530443
2530447
2530448
2530449
2530450
2530451
2530452
2530453
2530454
2530455
2530457
2530458
2530459
2530460
2530461
2530462
2530463
2530466
2530467
2530468
2530469
2530470
2530471
2530472
2530473
2530475
2530476
2530477
2530478
2530479
2530480
2530482
2530483
2530484
2530485
2530487
2530488
2530490
2530491
2530492
2530493
2530494
2530496
2530497
2530498
2530499
2530505
2530508
2530509
2530511
2530513
2530514
2530515
2530516
2530517
2530521
2530522
2530523
2530524
2530526
2530527
2530530
2530531
2530532
2530533
2530534
2530535
2530536
2530537
2530538
33561_at
33562_g_at
33563_s_at
8048782
83193_at
90615_at
A_24_P308469
GE63201
GO:0003013
GO:0005178
GO:0005198
GO:0005201
GO:0005515
GO:0005576
GO:0005581
GO:0005587
GO:0005604
GO:0005615
GO:0005783
GO:0005788
GO:0006919
GO:0007155
GO:0007166
GO:0007605
GO:0008015
GO:0008191
GO:0008285
GO:0009749
GO:0012501
GO:0016525
GO:0023052
GO:0030020
GO:0030198
GO:0030312
GO:0031012
GO:0032836
GO:0038063
GO:0043226
GO:0043231
GO:0048856
GO:0050877
GO:0062023
GO:0072577
GO:0098772
GO:1905563
HMNXSV003028772
HMNXSV003041056
Hs.150318.0.A1_3p_at
Hs.530.0.S2_3p_at
Hs.530.1.S1_3p_a_at
Hs.530.2.S1_3p_a_at
ILMN_1662731
ILMN_2272270
M81379_at
PH_hs_0024708
TC02001361.hg
Participates
as a member of
Alpha-3(IV) chains [endoplasmic reticulum lumen] (Homo sapiens)
as a candidate of
3,4-Hyp collagen propeptides [endoplasmic reticulum lumen] (Homo sapiens)
Other forms of this molecule
3x4Hyp-3Hyp-GlcGalHyl-COL4A3(29-1670) [endoplasmic reticulum lumen]
3x4Hyp-GlcGalHyl-COL4A3(29-1670) [endoplasmic reticulum lumen]
GlcGalHyl-COL4A3(29-1670) [endoplasmic reticulum lumen]
3x4Hyp-GalHyl-COL4A3(29-1670) [endoplasmic reticulum lumen]
3x4Hyp-3Hyp-GalHyl-COL4A3(29-1670) [endoplasmic reticulum lumen]
GalHyl-COL4A3(29-1670) [endoplasmic reticulum lumen]
COL4A3(29-1670) [endoplasmic reticulum lumen]
3x4Hyp-COL4A3(29-1670) [endoplasmic reticulum lumen]
3x4Hyp-5Hyl-COL4A3(29-1670) [endoplasmic reticulum lumen]
3x4Hyp-3Hyp-5Hyl-COL4A3(29-1670) [endoplasmic reticulum lumen]
5Hyl-COL4A3(29-1670) [endoplasmic reticulum lumen]
3,4-Hyp 5-sulfiliminyl collagen alpha-3(IV) chain [extracellular region]
5-sulfiliminyl collagen alpha-3(IV) chain [extracellular region]
4-Hyp 5-sulfiliminyl collagen alpha-3(IV) chain [extracellular region]
3x4Hyp-GalHyl-COL4A3(?-1670) [extracellular region]
GlcGalHyl-COL4A3(?-1670) [extracellular region]
GalHyl-COL4A3(?-1670) [extracellular region]
3x4Hyp-3Hyp-COL4A3(29-?) [extracellular region]
3x4Hyp-3Hyp-COL4A3(?-1670) [extracellular region]
3x4Hyp-COL4A3(?-1670) [extracellular region]
3x4Hyp-5Hyl-COL4A3(29-?) [extracellular region]
3x4Hyp-5Hyl-COL4A3(?-1670) [extracellular region]
3x4Hyp-GlcGalHyl-COL4A3(29-?) [extracellular region]
COL4A3(?-1670) [extracellular region]
3x4Hyp-GalHyl-COL4A3(29-?) [extracellular region]
3x4Hyp-3Hyp-GlcGalHyl-COL4A3(29-?) [extracellular region]
3x4Hyp-COL4A3(29-?) [extracellular region]
3x4Hyp-GlcGalHyl-COL4A3(?-1670) [extracellular region]
GlcGalHyl-COL4A3(29-?) [extracellular region]
3x4Hyp-3Hyp-5Hyl-COL4A3(?-1670) [extracellular region]
3x4Hyp-3Hyp-GlcGalHyl-COL4A3(?-1670) [extracellular region]
COL4A3(29-?) [extracellular region]
5Hyl-COL4A3(29-?) [extracellular region]
5Hyl-COL4A3(?-1670) [extracellular region]
GalHyl-COL4A3(29-?) [extracellular region]
3x4Hyp-3Hyp-GalHyl-COL4A3(?-1670) [extracellular region]
3x4Hyp-3Hyp-5Hyl-COL4A3(29-?) [extracellular region]
COL4A3(1426-1670) [extracellular region]
5Hyl-COL4A3(1426-1670) [extracellular region]
3x4Hyp-GalHyl-COL4A3(1426-1670) [extracellular region]
GlcGalHyl-COL4A3(1426-1670) [extracellular region]
GalHyl-COL4A3(1426-1670) [extracellular region]
3x4Hyp-GlcGalHyl-COL4A3(1426-1670) [extracellular region]
3x4Hyp-COL4A3(1426-1670) [extracellular region]
COL4A3(29-1670) [extracellular region]
GlcGalHyl-COL4A3(29-1670) [extracellular region]
3x4Hyp-GalHyl-COL4A3(29-1670) [extracellular region]
3x4Hyp-3Hyp-GalHyl-COL4A3(29-1670) [extracellular region]
3x4Hyp-3Hyp-GlcGalHyl-COL4A3(29-1670) [extracellular region]
3x4Hyp-5Hyl-COL4A3(29-1670) [extracellular region]
3x4Hyp-COL4A3(29-1670) [extracellular region]
3x4Hyp-3Hyp-5Hyl-COL4A3(29-1670) [extracellular region]
3x4Hyp-3Hyp-COL4A3(29-1670) [extracellular region]
3x4Hyp-GlcGalHyl-COL4A3(29-1670) [extracellular region]
5Hyl-COL4A3(29-1670) [extracellular region]
GalHyl-COL4A3(29-1670) [extracellular region]
3x4Hyp-3Hyp-5Hyl-COL4A3(1426-1670) [extracellular region]
3x4Hyp-3Hyp-GlcGalHyl-COL4A3(1426-1670) [extracellular region]
3x4Hyp-3Hyp-COL4A3(1426-1670) [extracellular region]
3x4Hyp-5Hyl-COL4A3(1426-1670) [extracellular region]
3x4Hyp-3Hyp-GalHyl-COL4A3(1426-1670) [extracellular region]
Inferred To
COL4A3 [endoplasmic reticulum lumen]
(Bos taurus)
COL4A3 [endoplasmic reticulum lumen]
(Canis familiaris)
COL4A3 [endoplasmic reticulum lumen]
(Sus scrofa)
Col4a3 [endoplasmic reticulum lumen]
(Mus musculus)
Col4a3 [endoplasmic reticulum lumen]
(Rattus norvegicus)
Modified Residues
Name
(2S,4R)-4-hydroxyproline at unknown position
PsiMod Name
(2S,4R)-4-hydroxyproline
PsiMod Definition
A protein modification that effectively converts an L-proline residue to 4-hydroxy-L-proline
Name
(2S,4R)-4-hydroxyproline at unknown position
PsiMod Name
(2S,4R)-4-hydroxyproline
PsiMod Definition
A protein modification that effectively converts an L-proline residue to 4-hydroxy-L-proline
Name
(2S,4R)-4-hydroxyproline at unknown position
PsiMod Name
(2S,4R)-4-hydroxyproline
PsiMod Definition
A protein modification that effectively converts an L-proline residue to 4-hydroxy-L-proline
Name
(2S,3S)-3-hydroxyproline at unknown position
PsiMod Name
(2S,3S)-3-hydroxyproline
PsiMod Definition
A protein modification that effectively converts an L-proline residue to 3-hydroxy-L-proline.
Cross References
RefSeq
NP_000082.2
OpenTargets
ENSG00000169031
GeneCards
Q01955
HPA
ENSG00000169031-COL4A3
Ensembl
ENSG00000169031
,
ENST00000396578
,
ENSP00000379823
PRO
Q01955
Pharos - Targets
Q01955
Orphanet
15772
PDB
6WKU
,
5NB0
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