CTSZ [plasma membrane]

Stable Identifier
R-HSA-2022345
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
Cathepsin Z, Cathepsin X, CATZ_HUMAN
Locations in the PathwayBrowser for interactor UniProt:Q5TD97 FHL5
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General
After secretion Cathepsin Z (Cathepsin X) is extracellular and associated with the plasma membrane.
Literature References
PubMed ID Title Journal Year
17065156 RGD-dependent binding of procathepsin X to integrin alphavbeta3 mediates cell-adhesive properties

Lechner, AM, Assfalg-Machleidt, I, Zahler, S, Stoeckelhuber, M, Machleidt, W, Jochum, M, Nägler, DK

J Biol Chem 2006
16376371 An enzyme-linked immunosorbent assay for human cathepsin X, a potential new inflammatory marker

Nägler, DK, Lechner, AM, Oettl, A, Kozaczynska, K, Scheuber, HP, Gippner-Steppert, C, Bogner, V, Biberthaler, P, Jochum, M

J Immunol Methods 2006
External Reference Information
External Reference
UniProt:Q9UBR2 CTSZ
Gene Names
CTSZ
Chain
signal peptide:1-23, propeptide:24-61, chain:62-303
Reference Genes
BioGPS Gene:1522 CTSZ
COSMIC (genes):CTSZ CTSZ
CTD Gene:1522 CTSZ
dbSNP Gene:1522 CTSZ
ENSEMBL:ENSG00000101160 CTSZ
HGNC:2547 CTSZ
KEGG:hsa:1522 CTSZ
Monarch:1522 CTSZ
NCBI Gene:1522 CTSZ
OMIM:603169 CTSZ
UCSC:Q9UBR2 CTSZ
Reference Transcript
Other Identifiers
11726594_at
1522
16920762
210042_PM_s_at
210042_s_at
3205250
32514_s_at
3911751
3911753
3911754
3911756
3911758
3911760
3911762
3911764
3911766
3911768
3911769
3911770
3911771
3911772
3911773
3911774
3911775
3911776
3911778
3911779
3911780
3911781
3911782
3911783
3911784
3946555
61829_at
8067279
A_23_P40240
A_33_P3250398
GE475635
GE816852
GO:0002003
GO:0004180
GO:0004197
GO:0005515
GO:0005576
GO:0005615
GO:0005764
GO:0005783
GO:0005788
GO:0005886
GO:0005938
GO:0006508
GO:0008233
GO:0008234
GO:0009986
GO:0010757
GO:0016787
GO:0016807
GO:0030134
GO:0030312
GO:0030426
GO:0031012
GO:0031410
GO:0033116
GO:0035580
GO:0051603
GO:0060441
GO:0070062
GO:1904813
HMNXSV003014927
HMNXSV003039493
ILMN_1666269
PH_hs_0013327
TC20000992.hg
TC20001680.hg
g3650497_3p_at
p28622
p33806
Other forms of this molecule
(Glc)3(GlcNAc)2(Man)9-CTSZ [endoplasmic reticulum lumen]
(Glc)3(GlcNAc)2(Man)9-CTSZ [COPII-coated ER to Golgi transport vesicle]
(Glc)3(GlcNAc)2(Man)9-CTSZ [endoplasmic reticulum-Golgi intermediate compartment membrane]
CTSZ [specific granule lumen]
CTSZ [extracellular region]
CTSZ [ficolin-1-rich granule lumen]
CTSZ [lysosomal lumen]
CTSZ [Golgi lumen]
Inferred To
CTSZ [plasma membrane] (Bos taurus)
CTSZ [plasma membrane] (Canis familiaris)
CTSZ [plasma membrane] (Sus scrofa)
ctsz [plasma membrane] (Danio rerio)
ctsz [plasma membrane] (Xenopus tropicalis)
Ctsz [plasma membrane] (Mus musculus)
Ctsz [plasma membrane] (Rattus norvegicus)
Cross References
RefSeq
Guide to Pharmacology - Targets
ENSEMBL
OpenTargets
ZINC - Substances
ZINC target
PRO
GlyGen
PDB
HPA
GeneCards
Pharos - Targets
ZINC - Predictions - Purchasable
Interactors (20)
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