CTSZ [plasma membrane]

Stable Identifier
R-HSA-2022345
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
Cathepsin Z, Cathepsin X, CATZ_HUMAN
Locations in the PathwayBrowser
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General

After secretion Cathepsin Z (Cathepsin X) is extracellular and associated with the plasma membrane.

Literature References
PubMed ID Title Journal Year
17065156 RGD-dependent binding of procathepsin X to integrin alphavbeta3 mediates cell-adhesive properties

Assfalg-Machleidt, I, Stoeckelhuber, M, Machleidt, W, Lechner, AM, Nägler, DK, Jochum, M, Zahler, S

J Biol Chem 2006
16376371 An enzyme-linked immunosorbent assay for human cathepsin X, a potential new inflammatory marker

Biberthaler, P, Scheuber, HP, Gippner-Steppert, C, Bogner, V, Kozaczynska, K, Oettl, A, Lechner, AM, Jochum, M, Nägler, DK

J Immunol Methods 2006
External Reference Information
External Reference
UniProt:Q9UBR2 CTSZ
Gene Names
CTSZ
Chain
signal peptide:1-23, propeptide:24-61, chain:62-303
Reference Genes
BioGPS Gene:1522 CTSZ
COSMIC (genes):CTSZ CTSZ
CTD Gene:1522 CTSZ
dbSNP Gene:1522 CTSZ
ENSEMBL:ENSG00000101160 CTSZ
ENSEMBL:ENSG00000101160.15 CTSZ
HGNC:2547 CTSZ
KEGG Gene (Homo sapiens):1522 CTSZ
Monarch:1522 CTSZ
NCBI Gene:1522 CTSZ
OMIM:603169 CTSZ
UCSC:Q9UBR2 CTSZ
Reference Transcript
Other Identifiers
11726594_at
1522
16920762
210042_PM_s_at
210042_s_at
32514_s_at
3911766
3911768
3911769
3911771
3911774
3911778
3911780
3911781
3911782
3911783
3911784
8067279
A_23_P40240
GO:0002003
GO:0003013
GO:0003824
GO:0004180
GO:0004197
GO:0005515
GO:0005576
GO:0005615
GO:0005764
GO:0005773
GO:0005783
GO:0005788
GO:0005886
GO:0005938
GO:0006508
GO:0008233
GO:0008234
GO:0010757
GO:0016787
GO:0030134
GO:0030163
GO:0030312
GO:0031012
GO:0031410
GO:0033116
GO:0035580
GO:0043226
GO:0043231
GO:0048856
GO:0050886
GO:0051603
GO:0051604
GO:0060441
GO:0062023
GO:0070062
GO:0140096
GO:1904813
HMNXSV003014927
ILMN_1666269
PH_hs_0013327
TC20000992.hg
g3650497_3p_at
Other forms of this molecule
(Glc)3(GlcNAc)2(Man)9-CTSZ [endoplasmic reticulum lumen]
(Glc)3(GlcNAc)2(Man)9-CTSZ [COPII-coated ER to Golgi transport vesicle]
(Glc)3(GlcNAc)2(Man)9-CTSZ [endoplasmic reticulum-Golgi intermediate compartment membrane]
CTSZ [ficolin-1-rich granule lumen]
CTSZ [extracellular region]
CTSZ [specific granule lumen]
CTSZ [lysosomal lumen]
CTSZ [Golgi lumen]
Inferred To
CTSZ [plasma membrane] (Bos taurus)
CTSZ [plasma membrane] (Canis familiaris)
CTSZ [plasma membrane] (Danio rerio)
CTSZ [plasma membrane] (Gallus gallus)
CTSZ [plasma membrane] (Sus scrofa)
ctsz [plasma membrane] (Xenopus tropicalis)
Ctsz [plasma membrane] (Mus musculus)
Ctsz [plasma membrane] (Rattus norvegicus)
Cross References
RefSeq
Guide to Pharmacology - Targets
OpenTargets
HPA
GeneCards
ZINC - Substances
ZINC target
Ensembl
PRO
Pharos - Targets
ZINC - Predictions - Purchasable
PDB
Interactors (20)
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