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3x4Hyp-COL3A1(24-1466) [endoplasmic reticulum lumen]
Stable Identifier
R-HSA-2022108
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
endoplasmic reticulum lumen
Synonyms
4-hydroxyprolyl collagen alpha-1(III) propeptide, CO3A1_HUMAN, COL3A1
Locations in the PathwayBrowser
Expand all
Extracellular matrix organization (Homo sapiens)
Collagen formation (Homo sapiens)
Collagen biosynthesis and modifying enzymes (Homo sapiens)
Collagen chain trimerization (Homo sapiens)
Association of procollagen type III (Homo sapiens)
Alpha-1(III) propeptides [endoplasmic reticulum lumen] (Homo sapiens)
3x4Hyp-COL3A1(24-1466) [endoplasmic reticulum lumen] (Homo sapiens)
C-linked procollagen type III trimer [endoplasmic reticulum lumen] (Homo sapiens)
Alpha-1(III) propeptides [endoplasmic reticulum lumen] (Homo sapiens)
3x4Hyp-COL3A1(24-1466) [endoplasmic reticulum lumen] (Homo sapiens)
Collagen prolyl 3-hydroxylase converts 4-Hyp collagen to 3,4-Hyp collagen (Homo sapiens)
Prolyl 3-hydroxylases:Fe2+:4-Hyp collagen propeptides [endoplasmic reticulum lumen] (Homo sapiens)
4-Hyp collagen propeptides [endoplasmic reticulum lumen] (Homo sapiens)
3x4Hyp-COL3A1(24-1466) [endoplasmic reticulum lumen] (Homo sapiens)
P3HB binds 4-Hyp-collagen propeptides (Homo sapiens)
4-Hyp collagen propeptides [endoplasmic reticulum lumen] (Homo sapiens)
3x4Hyp-COL3A1(24-1466) [endoplasmic reticulum lumen] (Homo sapiens)
Prolyl 3-hydroxylases:Fe2+:4-Hyp collagen propeptides [endoplasmic reticulum lumen] (Homo sapiens)
4-Hyp collagen propeptides [endoplasmic reticulum lumen] (Homo sapiens)
3x4Hyp-COL3A1(24-1466) [endoplasmic reticulum lumen] (Homo sapiens)
P4HB:4-Hyp collagen propeptides dissociates (Homo sapiens)
4-Hyp collagen propeptides [endoplasmic reticulum lumen] (Homo sapiens)
3x4Hyp-COL3A1(24-1466) [endoplasmic reticulum lumen] (Homo sapiens)
4-Hyp collagen propeptides:P4HB [endoplasmic reticulum lumen] (Homo sapiens)
4-Hyp collagen propeptides [endoplasmic reticulum lumen] (Homo sapiens)
3x4Hyp-COL3A1(24-1466) [endoplasmic reticulum lumen] (Homo sapiens)
Procollagen lysyl hydroxylases convert collagen lysines to 5-hydroxylysines (Homo sapiens)
Lysyl hydroxylases:Lysyl hydroxylase procollagen substrates [endoplasmic reticulum membrane] (Homo sapiens)
Lysyl hydroxylase procollagen substrates [endoplasmic reticulum lumen] (Homo sapiens)
4-Hyp collagen propeptides [endoplasmic reticulum lumen] (Homo sapiens)
3x4Hyp-COL3A1(24-1466) [endoplasmic reticulum lumen] (Homo sapiens)
Procollagen triple helix formation (Homo sapiens)
Collagen and procollagen triple helices:Serpin H1 [endoplasmic reticulum lumen] (Homo sapiens)
Collagen and procollagen triple helices [endoplasmic reticulum lumen] (Homo sapiens)
Fibrillar procollagen triple helices [endoplasmic reticulum lumen] (Homo sapiens)
Procollagen type III [endoplasmic reticulum lumen] (Homo sapiens)
Alpha-1(III) propeptides [endoplasmic reticulum lumen] (Homo sapiens)
3x4Hyp-COL3A1(24-1466) [endoplasmic reticulum lumen] (Homo sapiens)
Procollagen C-linked trimers [endoplasmic reticulum lumen] (Homo sapiens)
C-linked procollagen type III trimer [endoplasmic reticulum lumen] (Homo sapiens)
Alpha-1(III) propeptides [endoplasmic reticulum lumen] (Homo sapiens)
3x4Hyp-COL3A1(24-1466) [endoplasmic reticulum lumen] (Homo sapiens)
Prolyl 4-hydroxylase converts collagen prolines to 4-hydroxyprolines (Homo sapiens)
4-Hyp collagen propeptides:P4HB [endoplasmic reticulum lumen] (Homo sapiens)
4-Hyp collagen propeptides [endoplasmic reticulum lumen] (Homo sapiens)
3x4Hyp-COL3A1(24-1466) [endoplasmic reticulum lumen] (Homo sapiens)
Secretion of collagens (Homo sapiens)
Collagens and tropocollagens:Serpin H1 [endoplasmic reticulum lumen] (Homo sapiens)
Collagens and tropocollagens [endoplasmic reticulum lumen] (Homo sapiens)
Fibrillar procollagen triple helices [endoplasmic reticulum lumen] (Homo sapiens)
Procollagen type III [endoplasmic reticulum lumen] (Homo sapiens)
Alpha-1(III) propeptides [endoplasmic reticulum lumen] (Homo sapiens)
3x4Hyp-COL3A1(24-1466) [endoplasmic reticulum lumen] (Homo sapiens)
External Reference Information
External Reference
UniProt:P02461 COL3A1
Gene Names
COL3A1
Chain
signal peptide:1-23, propeptide:24-153, chain:154-1221, propeptide:1222-1466
Reference Genes
BioGPS Gene:1281 COL3A1
COSMIC (genes):COL3A1 COL3A1
CTD Gene:1281 COL3A1
dbSNP Gene:1281 COL3A1
ENSEMBL:ENSG00000168542 COL3A1
ENSEMBL_homo_sapiens_GENE:ENSG00000168542.17 COL3A1
HGNC:2201 COL3A1
KEGG Gene (Homo sapiens):1281 COL3A1
Monarch:1281 COL3A1
NCBI Gene:1281 COL3A1
OMIM:120180 COL3A1
UCSC:P02461 COL3A1
Reference Transcript
RefSeq:NM_000090.3 COL3A1
Other Identifiers
11715414_x_at
11715415_a_at
11744379_a_at
11744380_s_at
11758342_s_at
1281
16888610
201852_PM_x_at
201852_x_at
211161_PM_s_at
211161_s_at
215076_PM_s_at
215076_s_at
2519582
2519583
2519585
2519586
2519587
2519588
2519589
2519590
2519591
2519592
2519593
2519594
2519595
2519596
2519597
2519598
2519599
2519600
2519601
2519602
2519603
2519604
2519605
2519606
2519607
2519608
2519610
2519611
2519612
2519613
2519614
2519615
2519616
2519617
2519618
2519619
2519620
2519621
2519623
2519626
2519628
2519629
2519630
2519631
2519634
2519635
2519636
2519637
2519638
2519641
2519643
2519644
2519645
2519647
2519648
2519649
2519652
2519653
2519656
2519657
2519658
2519659
2519660
2519661
2519663
32488_at
8046922
A_14_P122278
A_24_P935491
GE79081
GO:0001568
GO:0001701
GO:0001764
GO:0001894
GO:0002020
GO:0002062
GO:0002376
GO:0005178
GO:0005198
GO:0005201
GO:0005515
GO:0005576
GO:0005581
GO:0005586
GO:0005615
GO:0005783
GO:0005788
GO:0007155
GO:0007160
GO:0007179
GO:0007229
GO:0007507
GO:0009314
GO:0010467
GO:0018149
GO:0021819
GO:0021987
GO:0023052
GO:0030020
GO:0030154
GO:0030168
GO:0030198
GO:0030199
GO:0030312
GO:0030324
GO:0031012
GO:0032905
GO:0034097
GO:0035025
GO:0035264
GO:0035904
GO:0036022
GO:0036211
GO:0042060
GO:0043226
GO:0043588
GO:0046332
GO:0046872
GO:0048144
GO:0048251
GO:0048407
GO:0048565
GO:0048856
GO:0048870
GO:0050777
GO:0051216
GO:0060350
GO:0060414
GO:0062023
GO:0071230
GO:0071711
GO:0097435
GO:1990776
GO:2001223
HMNXSV003027455
Hs.119571.0.A1_3p_s_at
Hs.297909.0.S1_3p_s_at
ILMN_1773079
PH_hs_0025910
TC02001105.hg
TC02003743.hg
TC02003744.hg
X06700_s_at
g11493468_3p_a_at
Participates
as a member of
Alpha-1(III) propeptides [endoplasmic reticulum lumen] (Homo sapiens)
as a candidate of
4-Hyp collagen propeptides [endoplasmic reticulum lumen] (Homo sapiens)
Other forms of this molecule
3x4Hyp-GlcGalHyl-COL3A1(24-1466) [endoplasmic reticulum lumen]
3x4Hyp-3Hyp-GlcGalHyl-COL3A1(24-1466) [endoplasmic reticulum lumen]
3x4Hyp-3Hyp-GalHyl-COL3A1(24-1466) [endoplasmic reticulum lumen]
3x4Hyp-GalHyl-COL3A1(24-1466) [endoplasmic reticulum lumen]
GalHyl-COL3A1(24-1466) [endoplasmic reticulum lumen]
GlcGalHyl-COL3A1(24-1466) [endoplasmic reticulum lumen]
COL3A1(24-1466) [endoplasmic reticulum lumen]
3x4Hyp-3Hyp-COL3A1(24-1466) [endoplasmic reticulum lumen]
3x4Hyp-5Hyl-COL3A1(24-1466) [endoplasmic reticulum lumen]
3x4Hyp-3Hyp-5Hyl-COL3A1(24-1466) [endoplasmic reticulum lumen]
5Hyl-COL3A1(24-1466) [endoplasmic reticulum lumen]
3x4Hyp-COL3A1(24-1466) [extracellular region]
3x4Hyp-5Hyl-COL3A1(24-1466) [extracellular region]
COL3A1(24-1466) [extracellular region]
3x4Hyp-3Hyp-COL3A1(24-1466) [extracellular region]
GlcGalHyl-COL3A1(24-1466) [extracellular region]
5Hyl-COL3A1(24-1466) [extracellular region]
3x4Hyp-GlcGalHyl-COL3A1(24-1466) [extracellular region]
3x4Hyp-3Hyp-GlcGalHyl-COL3A1(24-1466) [extracellular region]
3x4Hyp-3Hyp-5Hyl-COL3A1(24-1466) [extracellular region]
GalHyl-COL3A1(24-1466) [extracellular region]
3x4Hyp-GalHyl-COL3A1(24-1466) [extracellular region]
3x4Hyp-3Hyp-GalHyl-COL3A1(24-1466) [extracellular region]
3x4Hyp-5Hyl-COL3A1(154-1466) [extracellular region]
5Hyl-COL3A1(154-1466) [extracellular region]
GlcGalHyl-COL3A1(154-1466) [extracellular region]
3x4Hyp-3Hyp-GlcGalHyl-COL3A1(154-1466) [extracellular region]
3x4Hyp-3Hyp-5Hyl-COL3A1(154-1466) [extracellular region]
COL3A1(154-1466) [extracellular region]
3x4Hyp-3Hyp-COL3A1(154-1466) [extracellular region]
3x4Hyp-3Hyp-GalHyl-COL3A1(154-1466) [extracellular region]
3x4Hyp-GalHyl-COL3A1(154-1466) [extracellular region]
GalHyl-COL3A1(154-1466) [extracellular region]
3x4Hyp-GlcGalHyl-COL3A1(154-1466) [extracellular region]
3x4Hyp-COL3A1(154-1466) [extracellular region]
5Hyl-COL3A1(154-948) [extracellular region]
3x4Hyp-GalHyl-COL3A1(949-1221) [extracellular region]
3x4Hyp-COL3A1(154-948) [extracellular region]
3x4Hyp-GalHyl-COL3A1(154-948) [extracellular region]
3x4Hyp-3Hyp-GlcGalHyl-COL3A1(949-1221) [extracellular region]
3x4Hyp-COL3A1(949-1221) [extracellular region]
5Hyl-COL3A1(949-1221) [extracellular region]
3x4Hyp-3Hyp-GalHyl-COL3A1(154-948) [extracellular region]
GlcGalHyl-COL3A1(949-1241) [extracellular region]
3x4Hyp-3Hyp-COL3A1(949-1221) [extracellular region]
3x4Hyp-3Hyp-COL3A1(154-948) [extracellular region]
GalHyl-COL3A1(949-1221) [extracellular region]
COL3A1(949-1221) [extracellular region]
COL3A1(154-948) [extracellular region]
GalHyl-COL3A1(154-948) [extracellular region]
GlcGalHyl-COL3A1(154-948) [extracellular region]
3x4Hyp-5Hyl-COL3A1(154-948) [extracellular region]
3x4Hyp-5Hyl-COL3A1(949-1221) [extracellular region]
3x4Hyp-3Hyp-GalHyl-COL3A1(949-1221) [extracellular region]
3x4Hyp-3Hyp-5Hyl-COL3A1(949-1221) [extracellular region]
3x4Hyp-3Hyp-GlcGalHyl-COL3A1(154-948) [extracellular region]
3x4Hyp-3Hyp-5Hyl-COL3A1(154-948) [extracellular region]
3x4Hyp-GlcGalHyl-COL3A1(949-1221) [extracellular region]
3x4Hyp-GlcGalHyl-COL3A1(154-948) [extracellular region]
3x4Hyp-3Hyp-GlcGalHyl-COL3A1 [extracellular region]
3x4Hyp-3Hyp-COL3A1 [extracellular region]
COL3A1 [extracellular region]
3x4Hyp-COL3A1 [extracellular region]
3x4Hyp-3Hyp-5Hyl-COL3A1 [extracellular region]
3x4Hyp-GlcGalHyl-COL3A1 [extracellular region]
3x4Hyp-3Hyp-GalHyl-COL3A1 [extracellular region]
5Hyl-COL3A1 [extracellular region]
GlcGalHyl-COL3A1(154-1241) [extracellular region]
3x4Hyp-GalHyl-COL3A1 [extracellular region]
3x4Hyp-5Hyl-COL3A1 [extracellular region]
GalHyl-COL3A1 [extracellular region]
Inferred To
3x4Hyp-COL3A1(24-1466) [endoplasmic reticulum lumen]
(Mus musculus)
3x4Hyp-COL3A1(24-1466) [endoplasmic reticulum lumen]
(Rattus norvegicus)
COL3A1 [endoplasmic reticulum lumen]
(Bos taurus)
COL3A1 [endoplasmic reticulum lumen]
(Canis familiaris)
COL3A1 [endoplasmic reticulum lumen]
(Gallus gallus)
COL3A1 [endoplasmic reticulum lumen]
(Sus scrofa)
col3a1 [endoplasmic reticulum lumen]
(Xenopus tropicalis)
cle-1 [endoplasmic reticulum lumen]
(Caenorhabditis elegans)
Modified Residues
Name
(2S,4R)-4-hydroxyproline at unknown position
PsiMod Name
(2S,4R)-4-hydroxyproline
PsiMod Definition
A protein modification that effectively converts an L-proline residue to 4-hydroxy-L-proline
Name
(2S,4R)-4-hydroxyproline at unknown position
PsiMod Name
(2S,4R)-4-hydroxyproline
PsiMod Definition
A protein modification that effectively converts an L-proline residue to 4-hydroxy-L-proline
Name
(2S,4R)-4-hydroxyproline at unknown position
PsiMod Name
(2S,4R)-4-hydroxyproline
PsiMod Definition
A protein modification that effectively converts an L-proline residue to 4-hydroxy-L-proline
Cross References
RefSeq
NP_000081.1
OpenTargets
ENSG00000168542
GeneCards
P02461
HPA
ENSG00000168542-COL3A1
Ensembl
ENSG00000168542
,
ENST00000304636
,
ENSP00000304408
PRO
P02461
Pharos - Targets
P02461
Orphanet
15770
PDB
7XAN
,
4AK3
,
7WWR
,
4AE2
,
2V53
,
4GYX
,
6FZV
,
7WWS
,
3DMW
,
6FZW
,
4AEJ
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