Reactome | LOXL1(26-94) [extracellular region]

LOXL1(26-94) [extracellular region]

Stable Identifier

R-HSA-2022105

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

extracellular region

Synonyms

LOXL1 propeptide, Lysyl oxidase homolog 1, LOXL1_HUMAN, LOXL1

Locations in the PathwayBrowser

Expand all

Extracellular matrix organization (Homo sapiens)

- Collagen formation (Homo sapiens)
  - Assembly of collagen fibrils and other multimeric structures (Homo sapiens)
    - Crosslinking of collagen fibrils (Homo sapiens)
      - Prolysyl oxidase activation (Homo sapiens)
        
        Lysyl oxidase propeptides [extracellular region] (Homo sapiens)
        
        LOXL1(26-94) [extracellular region] (Homo sapiens)

External Reference Information

External Reference

UniProt:Q08397 LOXL1

Gene Names

LOXL1, LOXL

Chain

signal peptide:1-25, propeptide:26-95, chain:96-574

Reference Genes

BioGPS Gene:4016 LOXL1

COSMIC (genes):LOXL1 LOXL1

CTD Gene:4016 LOXL1

dbSNP Gene:4016 LOXL1

ENSEMBL:ENSG00000129038 LOXL1

ENSEMBL_homo_sapiens_GENE:ENSG00000129038.16 LOXL1

HGNC:6665 LOXL1

KEGG Gene (Homo sapiens):4016 LOXL1

Monarch:4016 LOXL1

NCBI Gene:4016 LOXL1

OMIM:153456 LOXL1

UCSC:Q08397 LOXL1

Reference Transcript

RefSeq:NM_005576.3 LOXL1

Other Identifiers

11717551_a_at

16802903

203570_PM_at

203570_at

3601349

3601350

3601351

3601352

3601353

3601354

3601355

3601356

3601357

3601358

3601359

3601360

3601369

3601371

3601372

3601375

3601376

3601377

3601379

36811_at

4016

7984771

87896_s_at

A_23_P124084

A_33_P3354464

GE60531

GO:0001669

GO:0003824

GO:0004720

GO:0005507

GO:0005515

GO:0005576

GO:0005604

GO:0005615

GO:0016491

GO:0016641

GO:0018277

GO:0030198

GO:0030199

GO:0030312

GO:0031012

GO:0031410

GO:0032496

GO:0035904

GO:0036211

GO:0043226

GO:0046872

GO:0048856

GO:0062023

GO:0140096

HMNXSV003020568

ILMN_1708363

ILMN_1734950

PH_hs_0004020

TC15000670.hg

U24389_s_at

g5031882_3p_at

Participates

as a member of

Lysyl oxidase propeptides [extracellular region] (Homo sapiens)

Other forms of this molecule

LOXL1(26-574) [extracellular region]

LOXL1 [extracellular region]

Inferred To

LOXL1(26-94) [extracellular region] (Gallus gallus)

LOXL1(26-94) [extracellular region] (Mus musculus)

Loxl2 [extracellular region] (Drosophila melanogaster)

loxl1 [extracellular region] (Danio rerio)

loxl1 [extracellular region] (Xenopus tropicalis)

Loxl1 [extracellular region] (Rattus norvegicus)

LOXL1 [extracellular region] (Bos taurus)

LOXL1 [extracellular region] (Canis familiaris)

LOXL1 [extracellular region] (Sus scrofa)

Cross References

RefSeq

NP_005567.2

OpenTargets

ENSG00000129038

HPA

ENSG00000129038-LOXL1

GeneCards

Q08397

Ensembl

ENSG00000129038, ENSP00000261921, ENST00000261921

PRO

Q08397

Pharos - Targets

Q08397

Orphanet

24677

HMDB Protein

HMDBP08249

Interactors (1)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P06276 BCHE	2	BCHE [extracellular region] (R-HSA-434469) BCHE [plasma membrane] (R-HSA-3640835)	0.527	2

Cite Us!