Reactome | LOXL4(25-?) [extracellular region]

LOXL4(25-?) [extracellular region]

Stable Identifier

R-HSA-2022087

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

extracellular region

Synonyms

LOXL4 propeptide, Lysyl oxidase homolog 4, LOXL4_HUMAN, LOXL4

Locations in the PathwayBrowser

Expand all

Extracellular matrix organization (Homo sapiens)

- Collagen formation (Homo sapiens)
  - Assembly of collagen fibrils and other multimeric structures (Homo sapiens)
    - Crosslinking of collagen fibrils (Homo sapiens)
      - Prolysyl oxidase activation (Homo sapiens)
        
        Lysyl oxidase propeptides [extracellular region] (Homo sapiens)
        
        LOXL4(25-?) [extracellular region] (Homo sapiens)

External Reference Information

External Reference

UniProt:Q96JB6 LOXL4

Gene Names

LOXL4, LOXC

Chain

signal peptide:1-24, chain:25-756

Reference Genes

BioGPS Gene:84171 LOXL4

COSMIC (genes):LOXL4 LOXL4

CTD Gene:84171 LOXL4

dbSNP Gene:84171 LOXL4

ENSEMBL:ENSG00000138131 LOXL4

HGNC:17171 LOXL4

KEGG Gene (Homo sapiens):84171 LOXL4

Monarch:84171 LOXL4

NCBI Gene:84171 LOXL4

OMIM:607318 LOXL4

UCSC:Q96JB6 LOXL4

Reference Transcript

RefSeq:NM_032211.6 LOXL4

Other Identifiers

0006220176

11727440_at

11727441_at

16717272

227145_at

3302694

3302695

3302696

3302697

3302698

3302699

3302700

3302703

3302704

3302706

3302709

3302710

3302711

3302713

3302714

3302715

3302716

3302717

3302718

3302719

3302721

62213_at

7935553

84171

A_23_P12755

A_24_P406754

GE87704

GO:0003674

GO:0004720

GO:0005044

GO:0005507

GO:0005515

GO:0005575

GO:0005576

GO:0005615

GO:0006464

GO:0006810

GO:0006897

GO:0008150

GO:0016020

GO:0016192

GO:0016491

GO:0016641

GO:0018057

GO:0030198

GO:0030199

GO:0032991

GO:0043167

GO:0043226

GO:0043235

GO:0046872

GO:0055114

GO:0070062

Hs.306814.0.S1_3p_at

ILMN_1754174

ILMN_2179083

PH_hs_0015787

TC10001576.hg

Participant Of

hasCandidate

Lysyl oxidase propeptides [extracellular region]

Other forms of this molecule

LOXL4 [extracellular region]

LOXL4(?-756) [extracellular region]

Inferred To

Homologues of LOXL4(25-?) [extracellular region] (Drosophila melanogaster)

LOXL4(25-?) [extracellular region] (Sus scrofa)

LOXL4(25-?) [extracellular region] (Xenopus tropicalis)

Loxl2 [extracellular region] (Drosophila melanogaster)

Loxl4 [extracellular region] (Mus musculus)

Loxl4 [extracellular region] (Rattus norvegicus)

loxl4 [extracellular region] (Danio rerio)

Loxl1 [extracellular region] (Drosophila melanogaster)

LOXL4 [extracellular region] (Canis familiaris)

LOXL4 [extracellular region] (Gallus gallus)

Cross References

RefSeq

NP_115587.6

OpenTargets

ENSG00000138131

HPA

ENSG00000138131-LOXL4

GeneCards

Q96JB6

Ensembl

ENSG00000138131, ENSP00000260702, ENST00000260702

PRO

Q96JB6

HMDB Protein

HMDBP08252

Interactors (2)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:O60341 KDM1A	1	KDM1A [nucleoplasm] (R-HSA-996769)	0.508	2
UniProt:Q96LA8 PRMT6	1	PRMT6 [nucleoplasm] (R-HSA-5226884)	0.508	2