DSPG and CSPG translocate to the lysosome for degradation

Stable Identifier
R-HSA-2022056
Type
Reaction [omitted]
Species
Homo sapiens
Compartment
ReviewStatus
5/5
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As part of the natural turnover of GAGs, extracellular KSPGs translocate to the lysosome to be degraded. The translocation process is unsure but could be either endocytosis from outside the cell or autophagy from inside the cell (Winchester 2005).
Literature References
PubMed ID Title Journal Year
15647514 Lysosomal metabolism of glycoproteins

Winchester, B

Glycobiology 2005
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