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CD3 epsilon: CD3 gamma with phosphorylated ITAM [plasma membrane]
Stable Identifier
R-HSA-202167
Type
Complex
Species
Homo sapiens
Compartment
plasma membrane
Locations in the PathwayBrowser
Expand all
Immune System (Homo sapiens)
Adaptive Immune System (Homo sapiens)
Costimulation by the CD28 family (Homo sapiens)
PD-1 signaling (Homo sapiens)
Dephosphorylation of CD3-zeta by PD-1 bound phosphatases (Homo sapiens)
Antigen-bearing MHC Class II: TCR with dephosphorylated CD3 zeta chain:CD4 [plasma membrane] (Homo sapiens)
T-cell receptor complex with dephosphorylated CD3 zeta chain [plasma membrane] (Homo sapiens)
CD3 epsilon: CD3 gamma with phosphorylated ITAM [plasma membrane] (Homo sapiens)
Antigen-bearing MHC Class II: TCR with phosphorylated ITAMs:CD4 [plasma membrane] (Homo sapiens)
T-cell receptor complex with phosphorylated ITAMs [plasma membrane] (Homo sapiens)
CD3 epsilon: CD3 gamma with phosphorylated ITAM [plasma membrane] (Homo sapiens)
TCR signaling (Homo sapiens)
Generation of second messenger molecules (Homo sapiens)
Phosphorylation of PLC-gamma1 (Homo sapiens)
ZAP-70 and ITK tyrosine kinases [plasma membrane] (Homo sapiens)
Activated ZAP-70 [plasma membrane] (Homo sapiens)
Antigen-bearing MHC Class II: TCR with phosphorylated ITAMs:CD4 [plasma membrane] (Homo sapiens)
T-cell receptor complex with phosphorylated ITAMs [plasma membrane] (Homo sapiens)
CD3 epsilon: CD3 gamma with phosphorylated ITAM [plasma membrane] (Homo sapiens)
Phosphorylation of SLP-76 (Homo sapiens)
Activated ZAP-70 [plasma membrane] (Homo sapiens)
Antigen-bearing MHC Class II: TCR with phosphorylated ITAMs:CD4 [plasma membrane] (Homo sapiens)
T-cell receptor complex with phosphorylated ITAMs [plasma membrane] (Homo sapiens)
CD3 epsilon: CD3 gamma with phosphorylated ITAM [plasma membrane] (Homo sapiens)
Phosphorylation of TBSMs in LAT (Homo sapiens)
Activated ZAP-70 [plasma membrane] (Homo sapiens)
Antigen-bearing MHC Class II: TCR with phosphorylated ITAMs:CD4 [plasma membrane] (Homo sapiens)
T-cell receptor complex with phosphorylated ITAMs [plasma membrane] (Homo sapiens)
CD3 epsilon: CD3 gamma with phosphorylated ITAM [plasma membrane] (Homo sapiens)
Phosphorylation of CD3 and TCR zeta chains (Homo sapiens)
Phosphorylation of ITAM motifs in CD3 complexes (Homo sapiens)
Antigen-bearing MHC Class II: TCR with phosphorylated ITAMs:CD4 [plasma membrane] (Homo sapiens)
T-cell receptor complex with phosphorylated ITAMs [plasma membrane] (Homo sapiens)
CD3 epsilon: CD3 gamma with phosphorylated ITAM [plasma membrane] (Homo sapiens)
Translocation of ZAP-70 to Immunological synapse (Homo sapiens)
Activation of ZAP-70 (Homo sapiens)
Activated ZAP-70 [plasma membrane] (Homo sapiens)
Antigen-bearing MHC Class II: TCR with phosphorylated ITAMs:CD4 [plasma membrane] (Homo sapiens)
T-cell receptor complex with phosphorylated ITAMs [plasma membrane] (Homo sapiens)
CD3 epsilon: CD3 gamma with phosphorylated ITAM [plasma membrane] (Homo sapiens)
phospho tyrosine ZAP-70 [plasma membrane] (Homo sapiens)
Antigen-bearing MHC Class II: TCR with phosphorylated ITAMs:CD4 [plasma membrane] (Homo sapiens)
T-cell receptor complex with phosphorylated ITAMs [plasma membrane] (Homo sapiens)
CD3 epsilon: CD3 gamma with phosphorylated ITAM [plasma membrane] (Homo sapiens)
PTPN22 dephosphorylates ZAP70 (Homo sapiens)
ZAP-70 bound to phosphorylated ITAM motifs [plasma membrane] (Homo sapiens)
Antigen-bearing MHC Class II: TCR with phosphorylated ITAMs:CD4 [plasma membrane] (Homo sapiens)
T-cell receptor complex with phosphorylated ITAMs [plasma membrane] (Homo sapiens)
CD3 epsilon: CD3 gamma with phosphorylated ITAM [plasma membrane] (Homo sapiens)
phospho tyrosine ZAP-70 [plasma membrane] (Homo sapiens)
Antigen-bearing MHC Class II: TCR with phosphorylated ITAMs:CD4 [plasma membrane] (Homo sapiens)
T-cell receptor complex with phosphorylated ITAMs [plasma membrane] (Homo sapiens)
CD3 epsilon: CD3 gamma with phosphorylated ITAM [plasma membrane] (Homo sapiens)
Phosphorylation of ZAP-70 by Lck (Homo sapiens)
ZAP-70 bound to phosphorylated ITAM motifs [plasma membrane] (Homo sapiens)
Antigen-bearing MHC Class II: TCR with phosphorylated ITAMs:CD4 [plasma membrane] (Homo sapiens)
T-cell receptor complex with phosphorylated ITAMs [plasma membrane] (Homo sapiens)
CD3 epsilon: CD3 gamma with phosphorylated ITAM [plasma membrane] (Homo sapiens)
phospho tyrosine ZAP-70 [plasma membrane] (Homo sapiens)
Antigen-bearing MHC Class II: TCR with phosphorylated ITAMs:CD4 [plasma membrane] (Homo sapiens)
T-cell receptor complex with phosphorylated ITAMs [plasma membrane] (Homo sapiens)
CD3 epsilon: CD3 gamma with phosphorylated ITAM [plasma membrane] (Homo sapiens)
Recruitment of ZAP-70 to phosphorylated ITAMs (Homo sapiens)
Antigen-bearing MHC Class II: TCR with phosphorylated ITAMs:CD4 [plasma membrane] (Homo sapiens)
T-cell receptor complex with phosphorylated ITAMs [plasma membrane] (Homo sapiens)
CD3 epsilon: CD3 gamma with phosphorylated ITAM [plasma membrane] (Homo sapiens)
ZAP-70 bound to phosphorylated ITAM motifs [plasma membrane] (Homo sapiens)
Antigen-bearing MHC Class II: TCR with phosphorylated ITAMs:CD4 [plasma membrane] (Homo sapiens)
T-cell receptor complex with phosphorylated ITAMs [plasma membrane] (Homo sapiens)
CD3 epsilon: CD3 gamma with phosphorylated ITAM [plasma membrane] (Homo sapiens)
Participants
components
p-Y160,Y171-CD3G [plasma membrane]
(Homo sapiens)
p-Y188,Y199-CD3E [plasma membrane]
(Homo sapiens)
Participates
as a component of
T-cell receptor complex with dephosphorylated CD3 zeta chain [plasma membrane] (Homo sapiens)
T-cell receptor complex with phosphorylated ITAMs [plasma membrane] (Homo sapiens)
Inferred To
CD3 epsilon: CD3 gamma with phosphorylated ITAM [plasma membrane]
(Bos taurus)
CD3 epsilon: CD3 gamma with phosphorylated ITAM [plasma membrane]
(Canis familiaris)
CD3 epsilon: CD3 gamma with phosphorylated ITAM [plasma membrane]
(Gallus gallus)
CD3 epsilon: CD3 gamma with phosphorylated ITAM [plasma membrane]
(Mus musculus)
CD3 epsilon: CD3 gamma with phosphorylated ITAM [plasma membrane]
(Rattus norvegicus)
CD3 epsilon: CD3 gamma with phosphorylated ITAM [plasma membrane]
(Sus scrofa)
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