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depalmitoylated eNOS translocates from plasma membrane
Stable Identifier
R-HSA-202132
Type
Reaction [uncertain]
Species
Homo sapiens
Compartment
Golgi membrane
,
plasma membrane
ReviewStatus
5/5
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Metabolism (Homo sapiens)
Metabolism of nitric oxide: NOS3 activation and regulation (Homo sapiens)
eNOS activation (Homo sapiens)
depalmitoylated eNOS translocates from plasma membrane (Homo sapiens)
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The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
Depalmitoylated, eNOS is thought to be displaced from the plasma membrane and redistributed to other intracellular membranes, including the Golgi, where re-palmitoylation occurs. The mechanism of transport from the plasma membrane is unknown.
Literature References
PubMed ID
Title
Journal
Year
10559837
Targeting and translocation of endothelial nitric oxide synthase
Michel, T
Braz J Med Biol Res
1999
Participants
Input
myristoylated eNOS dimer [cytosol]
(Homo sapiens)
Output
myristoylated eNOS dimer [Golgi membrane]
(Homo sapiens)
Participates
as an event of
eNOS activation (Homo sapiens)
Event Information
Go Biological Process
protein localization to Golgi membrane (1903292)
Orthologous Events
depalmitoylated eNOS translocates from plasma membrane (Bos taurus)
depalmitoylated eNOS translocates from plasma membrane (Dictyostelium discoideum)
depalmitoylated eNOS translocates from plasma membrane (Drosophila melanogaster)
depalmitoylated eNOS translocates from plasma membrane (Gallus gallus)
depalmitoylated eNOS translocates from plasma membrane (Mus musculus)
depalmitoylated eNOS translocates from plasma membrane (Plasmodium falciparum)
depalmitoylated eNOS translocates from plasma membrane (Rattus norvegicus)
depalmitoylated eNOS translocates from plasma membrane (Saccharomyces cerevisiae)
depalmitoylated eNOS translocates from plasma membrane (Schizosaccharomyces pombe)
depalmitoylated eNOS translocates from plasma membrane (Sus scrofa)
Authored
Hemish, J (2007-10-19)
Reviewed
Enikolopov, G (2008-02-28)
Created
Hemish, J (2007-10-19)
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