PPP3 complex dephosphorylates DARPP-32 on Thr34

Stable Identifier
R-HSA-201787
Type
Reaction [transition]
Species
Homo sapiens
Compartment
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Calcineurin has been identified as a Ca2+- and calmodulin-dependent phosphoprotein phosphatase. The concentration of the enzyme is relatively high in mammalian brain.

Literature References
PubMed ID Title Journal Year
6330098 Mammalian brain phosphoproteins as substrates for calcineurin

King, MM, Huang, CY, Chock, PB, Nairn, AC, Hemmings HC, Jr, Chan, KF, Greengard, P

J Biol Chem 1984
Participants
Participates
Catalyst Activity

protein serine/threonine phosphatase activity of PPP3 complex [cytosol]

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