PPP3 complex dephosphorylates DARPP-32 on Thr34

Stable Identifier
R-HSA-201787
Type
Reaction [transition]
Species
Homo sapiens
Compartment
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Calcineurin has been identified as a Ca2+- and calmodulin-dependent phosphoprotein phosphatase. The concentration of the enzyme is relatively high in mammalian brain.

Literature References
PubMed ID Title Journal Year
6330098 Mammalian brain phosphoproteins as substrates for calcineurin

King, MM, Huang, CY, Chock, PB, Nairn, AC, Hemmings HC, Jr, Chan, KF, Greengard, P

J Biol Chem 1984
Participants
Participant Of
hasEvent
Catalyst Activity
Catalyst Activity
Title
protein serine/threonine phosphatase activity of PPP3 complex [cytosol]
Physical Entity
Activity
Inferred From
Authored
Reviewed
Created