Reactome | PYGO1 [nucleoplasm]

PYGO1 [nucleoplasm]

Stable Identifier

R-HSA-201705

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q9Y3Y4 PYGO1

Gene Names

PYGO1

Chain

chain:1-419

Reference Genes

BioGPS Gene:26108 PYGO1

COSMIC (genes):PYGO1 PYGO1

CTD Gene:26108 PYGO1

dbSNP Gene:26108 PYGO1

ENSEMBL:ENSG00000171016 PYGO1

ENSEMBL_homo_sapiens_GENE:ENSG00000171016.13 PYGO1

HGNC:30256 PYGO1

KEGG Gene (Homo sapiens):26108 PYGO1

Monarch:26108 PYGO1

NCBI Gene:26108 PYGO1

OMIM:606902 PYGO1

UCSC:Q9Y3Y4 PYGO1

Reference Transcript

Other Identifiers

11715197_s_at

11759358_at

16809650

215517_PM_at

215517_at

239741_PM_at

239741_at

26108

32015_at

3625433

3625435

3625436

3625437

3625438

3625439

3625441

3625442

3625443

3625446

3625447

3625448

3625449

3625450

48287_at

55989_at

7989069

A_23_P364809

A_32_P193378

A_32_P530933

A_33_P3782469

GE532106

GE886450

GO:0001822

GO:0002244

GO:0005515

GO:0005634

GO:0005654

GO:0006351

GO:0006355

GO:0007286

GO:0007289

GO:0016055

GO:0022414

GO:0023052

GO:0030154

GO:0034504

GO:0035064

GO:0042393

GO:0043226

GO:0045944

GO:0046872

GO:0048856

GO:0060070

HMNXSV003034782

Hs.225984.0.S1_3p_at

Hs.87194.0.A1_3p_at

ILMN_1913641

ILMN_2179229

PH_hs_0004897

PH_hs_0023281

TC15001468.hg

TC15002548.hg

p25936

Participates

as a member of

PYGO [nucleoplasm] (Homo sapiens)

Inferred To

pygo-1 [nucleoplasm] (Caenorhabditis elegans)

pygo [nucleoplasm] (Drosophila melanogaster)

Homologues of PYGO1 [nucleoplasm] (Drosophila melanogaster)

PYGO1 [nucleoplasm] (Bos taurus)

PYGO1 [nucleoplasm] (Canis familiaris)

PYGO1 [nucleoplasm] (Gallus gallus)

PYGO1 [nucleoplasm] (Sus scrofa)

pygo1 [nucleoplasm] (Danio rerio)

lgs [nucleoplasm] (Drosophila melanogaster)

Pygo1 [nucleoplasm] (Mus musculus)

Pygo1 [nucleoplasm] (Rattus norvegicus)

Cross References

RefSeq

NP_001317255.1, XP_011519748.1, NP_056432.1

OpenTargets

ENSG00000171016

HPA

ENSG00000171016-PYGO1

GeneCards

Q9Y3Y4

Ensembl

ENST00000563719, ENST00000302000, ENSG00000171016, ENSP00000302327, ENSP00000496139, ENST00000645724, ENSP00000457777

PRO

Q9Y3Y4

Pharos - Targets

Q9Y3Y4

PDB

2VP7, 2VPD, 2VPG, 2VPB, 2VPE

Interactors (3)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P36957 DLST	5	Lipo-K110-DLST [mitochondrial matrix] (R-HSA-69993) SuccinyllipoH2-K110-DLST [mitochondrial matrix] (R-HSA-9853502) LipoH2-K110-DLST [mitochondrial matrix] (R-HSA-9853485) GlutaryllipoH2-K110-DLST [mitochondrial matrix] (R-HSA-9858581) DLST [mitochondrial matrix] (R-HSA-6792574)	0.556	3
UniProt:P61769 B2M	11	B2M(21-119) [early endosome membrane] (R-HSA-182298) B2M(21-119) [specific granule lumen] (R-HSA-6806144) B2M(21-119) [extracellular region] (R-HSA-1302721) B2M(21-119) [tertiary granule lumen] (R-HSA-6800179) B2M(21-119) [phagocytic vesicle membrane] (R-HSA-1236891) B2M(21-119) [recycling endosome membrane] (R-HSA-8863880) B2M(21-119) [early endosome lumen] (R-HSA-1236827) B2M(21-119) [Golgi membrane] (R-HSA-983403) B2M(21-119) [ER to Golgi transport vesicle membrane] (R-HSA-983378) B2M(21-119) [endoplasmic reticulum lumen] (R-HSA-983063) B2M(21-119) [plasma membrane] (R-HSA-167743)	0.556	3
UniProt:P27797 CALR	6	CALR [lumenal side of endoplasmic reticulum membrane] (R-HSA-985502) CALR [extracellular region] (R-HSA-2197641) CALR [endocytic vesicle lumen] (R-HSA-2239448) CALR [endoplasmic reticulum lumen] (R-HSA-195905) CALR [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-HSA-8863866) CALR [phagocytic vesicle membrane] (R-HSA-1236879)	0.556	3

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