Reactome | ZFYVE16 [early endosome membrane]

ZFYVE16 [early endosome membrane]

Stable Identifier

R-HSA-201645

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

early endosome membrane

Synonyms

Endofin, Zinc finger FYVE domain-containing protein 16, ZY16_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q7Z3T8 ZFYVE16

Gene Names

ZFYVE16, KIAA0305

Chain

chain:1-1539

Reference Genes

BioGPS Gene:9765 ZFYVE16

COSMIC (genes):ZFYVE16 ZFYVE16

CTD Gene:9765 ZFYVE16

dbSNP Gene:9765 ZFYVE16

ENSEMBL:ENSG00000039319 ZFYVE16

ENSEMBL_homo_sapiens_GENE:ENSG00000039319.17 ZFYVE16

HGNC:20756 ZFYVE16

KEGG Gene (Homo sapiens):9765 ZFYVE16

Monarch:9765 ZFYVE16

NCBI Gene:9765 ZFYVE16

OMIM:608880 ZFYVE16

UCSC:Q7Z3T8 ZFYVE16

Reference Transcript

Other Identifiers

11739855_a_at

11750632_a_at

11754534_a_at

16986700

203651_PM_at

203651_at

2817732

2817736

2817737

2817740

2817741

2817743

2817744

2817745

2817746

2817747

2817751

2817753

2817755

2817756

2817757

2817759

2817760

2817761

2817762

2817766

2817770

2817772

2817775

2817777

2817778

2817779

2817782

2817784

2817785

2817786

2817787

2817788

2817789

2817790

2817792

2817794

2817795

2817796

2817797

37914_at

42259_at

8106602

9765

A_14_P125384

A_14_P139609

A_23_P7543

A_24_P239531

A_24_P286054

A_24_P8349

GE528248

GE53044

GO:0005515

GO:0005545

GO:0005547

GO:0005737

GO:0005768

GO:0005769

GO:0005829

GO:0006622

GO:0006886

GO:0007165

GO:0008289

GO:0016020

GO:0016050

GO:0016192

GO:0016197

GO:0023052

GO:0030100

GO:0031410

GO:0031901

GO:0043226

GO:0043231

GO:0046872

HMNXSV003032437

HMNXSV003048716

ILMN_1651769

ILMN_2140999

PH_hs_0025659

TC05000398.hg

g7662047_3p_at

Participates

as an input of

An anchoring protein, Endofin, recruits R-Smad1/5/8 (Homo sapiens)

as a component of

Inferred To

Sara [early endosome membrane] (Drosophila melanogaster)

zfyve16 [early endosome membrane] (Xenopus tropicalis)

aka-1 [early endosome membrane] (Caenorhabditis elegans)

ZFYVE16 [early endosome membrane] (Bos taurus)

ZFYVE16 [early endosome membrane] (Canis familiaris)

ZFYVE16 [early endosome membrane] (Danio rerio)

ZFYVE16 [early endosome membrane] (Gallus gallus)

ZFYVE16 [early endosome membrane] (Mus musculus)

ZFYVE16 [early endosome membrane] (Sus scrofa)

Zfyve16 [early endosome membrane] (Rattus norvegicus)

Cross References

RefSeq

XP_011542055.1, XP_016865581.1, XP_016865580.1, NP_001271166.1, XP_005248689.1

OpenTargets

ENSG00000039319

HPA

ENSG00000039319-ZFYVE16

GeneCards

Q7Z3T8

Ensembl

ENST00000338008, ENSG00000039319, ENST00000510158, ENST00000505560, ENSP00000426848, ENSP00000337159, ENSP00000423663

PRO

Q7Z3T8

Pharos - Targets

Q7Z3T8

PDB

5MK0, 3T7L

Interactors (3)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:O60784 TOM1	3	TOM1 [azurophil granule membrane] (R-HSA-6799348) TOM1 [plasma membrane] (R-HSA-6806274) TOM1 [specific granule membrane] (R-HSA-6800923)	0.655	5
UniProt:P62136 PPP1CA	1	PPP1CA [cytosol] (R-HSA-163525)	0.547	2
UniProt:Q15075 EEA1	1	EEA1 [endosome membrane] (R-HSA-187893)	0.536	4

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